Zobrazeno 1 - 10
of 394
pro vyhledávání: '"Robert A. McPherson"'
Autor:
Rachy Abraham, Robert L. McPherson, Morgan Dasovich, Mohsen Badiee, Anthony K. L. Leung, Diane E. Griffin
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Macrodomain (MD), a highly conserved protein fold present in a subset of plus-strand RNA viruses, binds to and hydrolyzes ADP-ribose (ADPr) from ADP-ribosylated proteins. ADPr-binding by the alphavirus nonstructural protein 3 (nsP3) MD is ne
Externí odkaz:
https://doaj.org/article/f14fda4fa606414e8071d7efbec069d1
Autor:
Soumi Ghosh, Christian P. Ahearn, Christine R. Isabella, Victoria M. Marando, Gregory J. Dodge, Helen Bartlett, Robert L. McPherson, Amanda E. Dugan, Shikha Jain, Lubov Neznanova, Hervé Tettelin, Rachel Putnik, Catherine L. Grimes, Stefan Ruhl, Laura L. Kiessling, Barbara Imperiali
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The oral microbiome is critical to human health and disease, yet the role that host salivary proteins play in maintaining oral health is unclear. A highly expressed gene in human salivary glands encodes the lectin zymogen granule protein 16 homolog B
Autor:
Robert L. McPherson, Christine R. Isabella, Rebecca L. Walker, Dallis Sergio, Sunhee Bae, Tony Gaca, Smrithi Raman, Le Thanh Tu Nguyen, Darryl A. Wesener, Melanie Halim, Michael G. Wuo, Amanda Dugan, Robert Kerby, Soumi Ghosh, Federico E. Rey, Catherine Dhennezel, Gleb Pishchany, Hera Vlamakis, Eric J. Alm, Ramnik J. Xavier, Laura L. Kiessling
Soluble human lectins are critical components of innate immunity. Genetic models suggest lectins influence host-resident microbiota, but their specificity for commensal and mutualist species is understudied. Elucidating lectins’ roles in regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6480d9eb512b0d77c25c4a84f6ed5e76
https://doi.org/10.1101/2022.12.14.520458
https://doi.org/10.1101/2022.12.14.520458
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006864 (2018)
Externí odkaz:
https://doaj.org/article/1e1bc23367d34b66ac4d76401f970607
Publikováno v:
Contact Lens and Anterior Eye. 43:173-177
To compare the effects on ocular temperature and tear film parameters following a single application of a latent heat eyelid warming device at a range of temperature settings.Fifteen subjects were enrolled in a prospective, investigator-masked, rando
Publikováno v:
J Proteome Res
ADP-ribosylation refers to the post-translational modification of protein substrates with monomers or polymers of the small molecule ADP-ribose. ADP-ribosylation is enzymatically regulated and plays roles in cellular processes including DNA repair, n
Autor:
Veronica F. Busa, Barbara S. Slusher, Morgan Dasovich, Jürgen Bosch, Aravinth Kumar Jayabalan, Jack Wei, Ajit G. Thomas, Karli R Redinger, Takashi Tsukamoto, Shang-Jung Cheng, Brennan Murphy, Jack A Goodman, Robert Lyle McPherson, Anthony K.L. Leung, Junlin Zhuo
Macrodomains are a class of conserved ADP-ribosylhydrolases expressed by viruses of pandemic concern, including coronaviruses and alphaviruses. Viral macrodomains are critical for replication and virus-induced pathogenesis; therefore, these enzymes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d858df342bafdd113eb438d9f0eb438
https://doi.org/10.1101/2021.10.07.463234
https://doi.org/10.1101/2021.10.07.463234
Autor:
Norbert Schormann, Robert G. Hammond, Robert Lyle McPherson, Anthony K.L. Leung, Champion Deivanayagam, Margaret A. Johnson
Publikováno v:
Proc Natl Acad Sci U S A
Macrodomains are proteins that recognize and hydrolyze ADP ribose (ADPR) modifications of intracellular proteins. Macrodomains are implicated in viral genome replication and interference with host cell immune responses. They are important to the infe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77df8eeb4e19a89203a5eaeb4a2d2938
https://europepmc.org/articles/PMC7812796/
https://europepmc.org/articles/PMC7812796/
Autor:
Robert S. McPherson
Publikováno v:
American Nations ISBN: 9781003061618
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3041fecf6fc6587a270cdaf74f30474d
https://doi.org/10.4324/9781003061618-7
https://doi.org/10.4324/9781003061618-7