Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Robert A. Lux"'
Autor:
Michael Riedel, Chuanchau J. Jou, Shuping Lai, Robert L. Lux, Alonso P. Moreno, Kenneth W. Spitzer, Elizabeth Christians, Martin Tristani-Firouzi, Ivor J. Benjamin
Publikováno v:
Stem Cell Reports, Vol 3, Iss 1, Pp 131-141 (2014)
Advances in induced pluripotent stem cell (iPSC) technology have set the stage for routine derivation of patient- and disease-specific human iPSC-cardiomyocyte (CM) models for preclinical drug screening and personalized medicine approaches. Periphera
Externí odkaz:
https://doaj.org/article/23201f7a4c764602afb1f832f6abc455
Autor:
Mohammed A. Swid, Leif A. Havton, Peter Hanna, Elizabeth H. Smith, Sirisha Achanta, Jeffrey L. Ardell, John D. Tompkins, Pradeep S. Rajendran, Robert L. Lux, Natalia P. Biscola, Kalyanam Shivkumar, Alison Moss, Jin Chen, Joseph Hadaya, Jaclyn A. Brennan, Igor R. Efimov, Rajanikanth Vadigepalli, Zixi (Jack) Cheng, James S. Schwaber, Michael J. Dacey, Shaina Robbins, Donald B. Hoover, Shumpei Mori, Stanley G. Peirce
Publikováno v:
Circ Res
Circulation research, vol 128, iss 9
Circulation research, vol 128, iss 9
Rationale: Cardiac function is under exquisite intrinsic cardiac neural control. Neuroablative techniques to modulate control of cardiac function are currently being studied in patients, albeit with variable and sometimes deleterious results. Objecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5b1c049668192a7b1f2126ee974afa
https://doi.org/10.1161/circresaha.120.318458
https://doi.org/10.1161/circresaha.120.318458
Autor:
Taro Temma, Robert L. Lux, Koji Yoshie, Justin Hayase, Jason S. Bradfield, Kalyanam Shivkumar, Olujimi A. Ajijola
Publikováno v:
Heart rhythm.
Mapping techniques to identify diseased myocardial substrate during ventricular tachycardia ablation procedures remain limited.We hypothesized that tissue derivative of the voltage with respect to time (dV/dt), the slope of the unipolar ventricular e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78d15e4e22dd9ac76dcc897415db3bd
https://pubmed.ncbi.nlm.nih.gov/36270579
https://pubmed.ncbi.nlm.nih.gov/36270579
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100242 (2014)
The heartbeat arises rhythmically in the sino-atrial node (SAN) and then spreads regularly throughout the heart. The molecular mechanism underlying SAN rhythm has been attributed by recent studies to the interplay between two clocks, one involving th
Externí odkaz:
https://doaj.org/article/9e0500616f734958b69e65758f4f4118
Autor:
Robert L Lux, Christopher Todd Sower, Nancy Allen, Susan P Etheridge, Martin Tristani-Firouzi, Elizabeth V Saarel
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85689 (2014)
BACKGROUND: Precise measurement of the QT interval is often hampered by difficulty determining the end of the low amplitude T wave. Root mean square electrocardiography (RMS ECG) provides a novel alternative measure of ventricular repolarization. Exp
Externí odkaz:
https://doaj.org/article/09076ddccc624b5eb7568c9bbf2b234f
Autor:
Jonathan D. Hoang, Kentaro Yamakawa, Pradeep S. Rajendran, Christopher A. Chan, Daigo Yagishita, Keijiro Nakamura, Robert L. Lux, Marmar Vaseghi
Publikováno v:
JACC. Clinical electrophysiology, vol 8, iss 4
JACC Clin Electrophysiol
JACC Clin Electrophysiol
ObjectivesThe goal of this study was to evaluate whether intermittent VNS reduces electrical heterogeneities and arrhythmia inducibility during sympathoexcitation.BackgroundSympathoexcitation increases the risk of ventricular tachyarrhythmias (VT). V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a824ed250ca95bdb6c79736d4bd6317
https://doi.org/10.2139/ssrn.3950133
https://doi.org/10.2139/ssrn.3950133
Autor:
Elizabeth H. Smith, John D. Tompkins, Zixi (Jack) Cheng, James S. Schwaber, Mohammed A. Swid, Leif A. Havton, Peter Hanna, Donald B. Hoover, Pradeep S. Rajendran, Jeffrey L. Ardell, Robert L. Lux, Michael J. Dacey, Jaclyn A. Brennan, Shaina Robbins, Igor R. Efimov, Natalia P. Biscola, Sirisha Achanta, Shumpei Mori, Alison Moss, Stanley G. Peirce, Joseph Hadaya, Kalyanam Shivkumar, Rajanikanth Vadigepalli, Jin Chen
Cardiac function is under exquisite intrinsic cardiac neural control. Neuroablative techniques to modulate control of cardiac function are currently being studied in patients, albeit with variable and sometimes deleterious results. Recognizing the ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98ccdafbf169dcf7797f2ef4a767cea8
https://doi.org/10.1101/2020.10.28.359109
https://doi.org/10.1101/2020.10.28.359109
Publikováno v:
Medical & Biological Engineering & Computing. 56:1-12
Mild-to-moderate ischemia does not result in ST segment elevation on the electrocardiogram (ECG), but rather non-specific changes in the T wave, which are frequently labeled as non-diagnostic for ischemia. Robust methods to quantify such T wave heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede33e0c0b2a3f12d0754067ba5a9f00
https://doi.org/10.1007/s11517-017-1659-1
https://doi.org/10.1007/s11517-017-1659-1
Autor:
Robert L. Lux, Iain Guy Strachan, Brock E. Heinz, Martino Vaglio, Jay W. Mason, Benhur Aysin, Thomas E. Moon, Fabio Badilini
Publikováno v:
Journal of Electrocardiology. 49:362-370
Background Existence of a relationship between the electrocardiographic QRS interval duration and the diurnally varying heart rate, of consistent sign and magnitude, is controversial and the relationship has not been fully characterized in normal pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::871ce8ff6aa283f66c82c787b3671eab
https://doi.org/10.1016/j.jelectrocard.2016.03.008
https://doi.org/10.1016/j.jelectrocard.2016.03.008
Autor:
Robert L. Lux
Publikováno v:
Journal of electrocardiology. 50(6)
Ventricular repolarization and its manifestation in the T wave of the electrocardiogram have long been a focus of clinical and experimental electrocardiology. In this short article, we shall review the basics of cellular and organ repolarization elec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76d4afbf9a5cde55151430adc2932c6
https://pubmed.ncbi.nlm.nih.gov/28803619
https://pubmed.ncbi.nlm.nih.gov/28803619