Zobrazeno 1 - 10
of 1 675
pro vyhledávání: '"Robert A. Kaplan"'
Autor:
Sairam Behera, Jonathan R. Belyeu, Xiao Chen, Luis F. Paulin, Ngoc Quynh H. Nguyen, Emma Newman, Medhat Mahmoud, Vipin K. Menon, Qibin Qi, Parag Joshi, Santica Marcovina, Massimiliano Rossi, Eric Roller, James Han, Vitor Onuchic, Christy L. Avery, Christie M. Ballantyne, Carlos J. Rodriguez, Robert C. Kaplan, Donna M. Muzny, Ginger A. Metcalf, Richard A. Gibbs, Bing Yu, Eric Boerwinkle, Michael A. Eberle, Fritz J. Sedlazeck
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract The abundance of Lp(a) protein holds significant implications for the risk of cardiovascular disease (CVD), which is directly impacted by the copy number (CN) of KIV-2, a 5.5 kbp sub-region. KIV-2 is highly polymorphic in the population and
Externí odkaz:
https://doaj.org/article/b08e11c0c6a64b4e840870232441e2bd
Autor:
Kai Luo, Alkis Taryn, Eun-Hye Moon, Brandilyn A. Peters, Scott D. Solomon, Martha L. Daviglus, Mayank M. Kansal, Bharat Thyagarajan, Marc D. Gellman, Jianwen Cai, Robert D. Burk, Rob Knight, Robert C. Kaplan, Susan Cheng, Carlos J. Rodriguez, Qibin Qi, Bing Yu
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract Background Left ventricular diastolic dysfunction (LVDD) is an important precursor of heart failure (HF), but little is known about its relationship with gut dysbiosis and microbial-related metabolites. By leveraging the multi-omics data fro
Externí odkaz:
https://doaj.org/article/0605ae6bad3d410f866c056035d292cb
Autor:
Kai Luo, Brandilyn A. Peters, Jee-Young Moon, Xiaonan Xue, Zheng Wang, Mykhaylo Usyk, David B. Hanna, Alan L. Landay, Michael F. Schneider, Deborah Gustafson, Kathleen M. Weber, Audrey French, Anjali Sharma, Kathryn Anastos, Tao Wang, Todd Brown, Clary B. Clish, Robert C. Kaplan, Rob Knight, Robert D. Burk, Qibin Qi
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Gut dysbiosis has been linked with both HIV infection and diabetes, but its interplay with metabolic and inflammatory responses in diabetes, particularly in the context of HIV infection, remains unclear. Methods We first conducted
Externí odkaz:
https://doaj.org/article/ddd735eae386481991401f432e4d62a0
Autor:
Paola Filigrana, Jee‐Young Moon, Linda C. Gallo, Lindsay Fernández‐Rhodes, Krista M. Perreira, Martha L. Daviglus, Bharat Thyagarajan, Olga L. Garcia‐Bedoya, Jianwen Cai, Xiaonan Xue, Robert C. Kaplan, Shakira Suglia, Carmen R. Isasi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 16 (2024)
Background The Hispanic/Latino population experiences socioeconomic disadvantages across the lifespan. Yet, little is known about the role of these disadvantages in cardiovascular health (CVH). We assessed the association of lifecourse socioeconomic
Externí odkaz:
https://doaj.org/article/9023b278ea0a4b90a1ec529e2ef959b0
Autor:
Yasmin Mossavar-Rahmani, Juan Lin, Stephanie Pan, Rebecca J. Song, Xiaonan Xue, Nicole L. Spartano, Vanessa Xanthakis, Daniela Sotres-Alvarez, David X. Marquez, Martha Daviglus, Jordan A. Carlson, Humberto Parada, Kelly R. Evenson, Ana C. Talavera, Marc Gellman, Krista M. Perreira, Linda C. Gallo, Ramachandran S. Vasan, Robert C. Kaplan
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background Physical activity promotes health and is particularly important during middle and older age for decreasing morbidity and mortality. We assessed the correlates of changes over time in moderate-to-vigorous physical activity (MVPA) i
Externí odkaz:
https://doaj.org/article/40e05441211a4c9b81c5dbc6ba037b4d
Autor:
Aditya Narayan, Margo Goncharova, Max Goncharov, Andrew Gostine, Nirav R. Shah, Robert M. Kaplan
Publikováno v:
Frontiers in Public Health, Vol 11 (2024)
Accurate observation of patient functioning is necessary for rigorous clinical research and for improving the quality of patient care. However, clinic or laboratory environments systematically differ from the contexts of everyday life. Further, asses
Externí odkaz:
https://doaj.org/article/bdb558edd5cf4f77b542ecaecb23ab3b
Autor:
Nuzulul Kurniansyah, Matthew O. Goodman, Alyna T. Khan, Jiongming Wang, Elena Feofanova, Joshua C. Bis, Kerri L. Wiggins, Jennifer E. Huffman, Tanika Kelly, Tali Elfassy, Xiuqing Guo, Walter Palmas, Henry J. Lin, Shih-Jen Hwang, Yan Gao, Kendra Young, Gregory L. Kinney, Jennifer A. Smith, Bing Yu, Simin Liu, Sylvia Wassertheil-Smoller, JoAnn E. Manson, Xiaofeng Zhu, Yii-Der Ida Chen, I-Te Lee, C. Charles Gu, Donald M. Lloyd-Jones, Sebastian Zöllner, Myriam Fornage, Charles Kooperberg, Adolfo Correa, Bruce M. Psaty, Donna K. Arnett, Carmen R. Isasi, Stephen S. Rich, Robert C. Kaplan, Susan Redline, Braxton D. Mitchell, Nora Franceschini, Daniel Levy, Jerome I. Rotter, Alanna C. Morrison, Tamar Sofer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract We assess performance and limitations of polygenic risk scores (PRSs) for multiple blood pressure (BP) phenotypes in diverse population groups. We compare “clumping-and-thresholding” (PRSice2) and LD-based (LDPred2) methods to construct
Externí odkaz:
https://doaj.org/article/d721f599909e48e7aa862786e05f3dd9
Autor:
Zheng Wang, Brandilyn A. Peters, MacKenzie Bryant, David B. Hanna, Tara Schwartz, Tao Wang, Christopher C. Sollecito, Mykhaylo Usyk, Evan Grassi, Fanua Wiek, Lauren St. Peter, Wendy S. Post, Alan L. Landay, Howard N. Hodis, Kathleen M. Weber, Audrey French, Elizabeth T. Golub, Jason Lazar, Deborah Gustafson, Anjali Sharma, Kathryn Anastos, Clary B. Clish, Robert D. Burk, Robert C. Kaplan, Rob Knight, Qibin Qi
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Background Alterations in gut microbiota have been implicated in HIV infection and cardiovascular disease. However, how gut microbial alterations relate to host inflammation and metabolite profiles, and their relationships with atheroscleros
Externí odkaz:
https://doaj.org/article/da80297957c64761a09224215e94a1c0
Autor:
Aimee J. Lansdale, Robert M. Kaplan
Publikováno v:
BMC Health Services Research, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Objective To investigate competing explanations for why Medicare Fee for Service (FFS) and private sector payments lead to hospital cost variations in Californian counties. Data sources Ratios of private to Medicare hospital costs were obtai
Externí odkaz:
https://doaj.org/article/d18772b0db174ddf80163407f1898ddd
Autor:
Hongjiao Liu, Wodan Ling, Xing Hua, Jee-Young Moon, Jessica S. Williams-Nguyen, Xiang Zhan, Anna M. Plantinga, Ni Zhao, Angela Zhang, Rob Knight, Qibin Qi, Robert D. Burk, Robert C. Kaplan, Michael C. Wu
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract Background Understanding human genetic influences on the gut microbiota helps elucidate the mechanisms by which genetics may influence health outcomes. Typical microbiome genome-wide association studies (GWAS) marginally assess the associati
Externí odkaz:
https://doaj.org/article/198f7a84d6c048ee9cd0fcb3451401e4