Zobrazeno 1 - 10
of 442
pro vyhledávání: '"Robert A. Henning"'
Publikováno v:
The Scientific World Journal, Vol 2015 (2015)
One potential way that healthy organizations can impact employee health is by promoting a climate for health within the organization. Using a definition of health climate that includes support for health from multiple levels within the organization,
Externí odkaz:
https://doaj.org/article/353d7274dbaf4187b3f570810a220ef9
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/ee6781d79a524fc2b06120b92d98b73c
Publikováno v:
Frontiers in Neuroanatomy, Vol 18 (2024)
Hibernating animals demonstrate a remarkable ability to withstand extreme physiological brain changes without triggering adverse neuroinflammatory responses. While hibernators may offer valuable insights into the neuroprotective mechanisms inherent t
Externí odkaz:
https://doaj.org/article/946126b749954907beadf5cb3975b4d4
Autor:
Robert W. Henning, Irina Kosheleva, Vukica Šrajer, In-Sik Kim, Eric Zoellner, Rama Ranganathan
Publikováno v:
Structural Dynamics, Vol 11, Iss 1, Pp 014301-014301-15 (2024)
A major goal in biomedical science is to move beyond static images of proteins and other biological macromolecules to the internal dynamics underlying their function. This level of study is necessary to understand how these molecules work and to engi
Externí odkaz:
https://doaj.org/article/0dfc439752524ddc9304d7b24acd7f47
Autor:
Christina F. de Veij Mestdagh, Frank Koopmans, Jonathan C. Breiter, Jaap A. Timmerman, Pieter C. Vogelaar, Guido Krenning, Huibert D. Mansvelder, August B. Smit, Robert H. Henning, Ronald E. van Kesteren
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-17 (2022)
Abstract Background Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease worldwide and remains without effective cure. Increasing evidence is supporting the mitochondrial cascade hypothesis, proposing that loss of mitochondrial
Externí odkaz:
https://doaj.org/article/57d2e632022d4d42b3829a94237d7099
Autor:
Tadeo Moreno-Chicano, Leiah M. Carey, Danny Axford, John H. Beale, R. Bruce Doak, Helen M. E. Duyvesteyn, Ali Ebrahim, Robert W. Henning, Diana C. F. Monteiro, Dean A. Myles, Shigeki Owada, Darren A. Sherrell, Megan L. Straw, Vukica Šrajer, Hiroshi Sugimoto, Kensuke Tono, Takehiko Tosha, Ivo Tews, Martin Trebbin, Richard W. Strange, Kevin L. Weiss, Jonathan A. R. Worrall, Flora Meilleur, Robin L. Owen, Reza A. Ghiladi, Michael A. Hough
Publikováno v:
IUCrJ, Vol 9, Iss 5, Pp 610-624 (2022)
Room-temperature macromolecular crystallography allows protein structures to be determined under close-to-physiological conditions, permits dynamic freedom in protein motions and enables time-resolved studies. In the case of metalloenzymes that are h
Externí odkaz:
https://doaj.org/article/288bb78b21864584a71fa98e261fa74e
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Hibernating mammals have developed many physiological adaptations to accommodate their decreased metabolism, body temperature, heart rate and prolonged immobility without suffering organ injury. During hibernation, the animals must suppress blood clo
Externí odkaz:
https://doaj.org/article/a47c8b08ef084e75b950b54e951782be
Publikováno v:
Cells, Vol 13, Iss 1, p 12 (2023)
Alzheimer’s disease (AD) is the most common cause of dementia worldwide and yet remains without effective therapy. Amongst the many proposed causes of AD, the mitochondrial cascade hypothesis is gaining attention. Accumulating evidence shows that m
Externí odkaz:
https://doaj.org/article/a83b6619eebc4dc4878643e2b1a315ce
Autor:
Christina F. de Veij Mestdagh, Jaap A. Timmerman, Frank Koopmans, Iryna Paliukhovich, Suzanne S. M. Miedema, Maaike Goris, Rolinka J. van der Loo, Guido Krenning, Ka Wan Li, Huibert D. Mansvelder, August B. Smit, Robert H. Henning, Ronald E. van Kesteren
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Hibernation induces neurodegeneration-like changes in the brain, which are completely reversed upon arousal. Hibernation-induced plasticity may therefore be of great relevance for the treatment of neurodegenerative diseases, but remains larg
Externí odkaz:
https://doaj.org/article/79d911a2ec34496183b119acd53c6f51
Autor:
Marziyeh Tolouee, Koen D. W. Hendriks, Fia Fia Lie, Lucas P. Gartzke, Maaike Goris, Femke Hoogstra-Berends, Steven Bergink, Robert H. Henning
Publikováno v:
Cell Transplantation, Vol 31 (2022)
Cooling at 4°C is routinely used to lower metabolism and preserve cell and tissue integrity in laboratory and clinical settings, including organ transplantation. However, cooling and rewarming produce cell damage, attributed primarily to a burst of
Externí odkaz:
https://doaj.org/article/c756303882ec4058bd4fb4dc35d03866