Zobrazeno 1 - 10
of 986
pro vyhledávání: '"Robert A. Colvin"'
Autor:
Zeguo Sun, Zhongyang Zhang, Khadija Banu, Ian W. Gibson, Robert B. Colvin, Zhengzi Yi, Weijia Zhang, Bony De Kumar, Anand Reghuvaran, John Pell, Thomas D. Manes, Arjang Djamali, Lorenzo Gallon, Philip J. O’Connell, John Cijiang He, Jordan S. Pober, Peter S. Heeger, Madhav C. Menon
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Donor-recipient (D-R) mismatches outside of human leukocyte antigens (HLAs) contribute to kidney allograft loss, but the mechanisms remain unclear, specifically for intronic mismatches. We quantified non-HLA mismatches at variant-, gene-, and genome-
Externí odkaz:
https://doaj.org/article/1062a57a1df84d2eb0cec1a6f8b62c10
Autor:
Dennis G. Moledina, Wassim Obeid, Rex N. Smith, Ivy Rosales, Meghan E. Sise, Gilbert Moeckel, Michael Kashgarian, Michael Kuperman, Kirk N. Campbell, Sean Lefferts, Kristin Meliambro, Markus Bitzer, Mark A. Perazella, Randy L. Luciano, Jordan S. Pober, Lloyd G. Cantley, Robert B. Colvin, F. Perry Wilson, Chirag R. Parikh
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Background Acute tubulointerstitial nephritis (AIN) is one of the few causes of acute kidney injury with diagnosis-specific treatment options. However, due to the need to obtain a kidney biopsy for histological confirmation, AIN diagnosis can be dela
Externí odkaz:
https://doaj.org/article/8efe2f2685704f25a2ece87934b2792f
Autor:
Sandra M Herrmann, Riley Fadden, Ryan J Sullivan, Kerry L Reynolds, Harish Seethapathy, Meghan E Sise, Shruti Gupta, Alexandra-Chloe Villani, Qiyu Wang, Daiana Moreno, Destiny Harden, R Neal Smith, Ivy A Rosales, Robert B Colvin, Sarah Chute, Lynn D Cornell, Nancy J Yang, Sara Barmettler, Sophia Wells, Jocelyn Farmer
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)
Background Non-invasive biomarkers of immune checkpoint inhibitor-associated acute tubulointerstitial nephritis (ICI-nephritis) are urgently needed. Because ICIs block immune checkpoint pathways that include cytotoxic T lymphocyte antigen 4 (CTLA4),
Externí odkaz:
https://doaj.org/article/b2896a0a2c844123a9938a6aff85c060
Autor:
Alexandre G. Lellouch, Alec R. Andrews, Gaelle Saviane, Zhi Yang Ng, Ilse M. Schol, Marion Goutard, Amon-Ra Gama, Ivy A. Rosales, Robert B. Colvin, Laurent A. Lantieri, Mark A. Randolph, Gilles Benichou, Curtis L. Cetrulo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundVascularized composite allografts (VCAs) allow reconstruction of devastating injuries and amputations, yet require lifelong immunosuppression that is associated with significant morbidity. Induction of immune tolerance of VCAs would permit
Externí odkaz:
https://doaj.org/article/9edd525b71754b0d840e1d03aaddef28
Autor:
Niyati Desai, Azfar Neyaz, Annamaria Szabolcs, Angela R. Shih, Jonathan H. Chen, Vishal Thapar, Linda T. Nieman, Alexander Solovyov, Arnav Mehta, David J. Lieb, Anupriya S. Kulkarni, Christopher Jaicks, Katherine H. Xu, Michael J. Raabe, Christopher J. Pinto, Dejan Juric, Ivan Chebib, Robert B. Colvin, Arthur Y. Kim, Robert Monroe, Sarah E. Warren, Patrick Danaher, Jason W. Reeves, Jingjing Gong, Erroll H. Rueckert, Benjamin D. Greenbaum, Nir Hacohen, Stephen M. Lagana, Miguel N. Rivera, Lynette M. Sholl, James R. Stone, David T. Ting, Vikram Deshpande
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Understanding the pathology in the lungs of patients with COVID-19 might provide clues as to the susceptibility of patients and how the SARS-CoV-2 virus can be fatal. Here the authors analyze cadaveric pulmonary tissue and show one group with high vi
Externí odkaz:
https://doaj.org/article/c26ed9e652d143d4a25413482e8fff81
Autor:
Chao Yang, Jifu Ge, Ivy Rosales, Qing Yuan, Edward Szuter, Ellen Acheampong, Paul S. Russell, Joren C. Madsen, Robert B. Colvin, Alessandro Alessandrini
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
In swine and nonhuman primates, kidney allografts can induce tolerance of heart allografts, leading to their long-term, immunosuppression-free survival. We refer to this phenomenon as kidney-induced cardiac allograft tolerance (KICAT). In this study,
Externí odkaz:
https://doaj.org/article/017512e7325243fcbc0d368cbe68d8d1
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 282, Iss Proc. Refine 2018, Pp 53-67 (2018)
In this paper we develop a theory for correctness of concurrent objects under weak memory models. Central to our definitions is the concept of observations which determine when effects of operations become visible, and hence determine the semantics o
Externí odkaz:
https://doaj.org/article/97267bc5017d46e78afca7126162021b
Autor:
Raphael Schiffmann, Daniel G. Bichet, Ana Jovanovic, Derralynn A. Hughes, Roberto Giugliani, Ulla Feldt-Rasmussen, Suma P. Shankar, Laura Barisoni, Robert B. Colvin, J. Charles Jennette, Fred Holdbrook, Andrew Mulberg, Jeffrey P. Castelli, Nina Skuban, Jay A. Barth, Kathleen Nicholls
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 13, Iss 1, Pp 1-7 (2018)
Abstract Background Fabry disease is frequently characterized by gastrointestinal symptoms, including diarrhea. Migalastat is an orally-administered small molecule approved to treat the symptoms of Fabry disease in patients with amenable mutations. M
Externí odkaz:
https://doaj.org/article/5e779a69a2964f6c8462aa2e8b74ad76
Autor:
Shunsaku Goto, Robert M. H. Grange, Riccardo Pinciroli, Ivy A. Rosales, Rebecca Li, Sophie L. Boerboom, Katrina F. Ostrom, Eizo Marutani, Hatus V. Wanderley, Aranya Bagchi, Robert B. Colvin, Lorenzo Berra, Olga Minaeva, Lee E. Goldstein, Rajeev Malhotra, Warren M. Zapol, Fumito Ichinose, Binglan Yu
Publikováno v:
Archives of Toxicology. 96:3363-3371
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a3aaaa843934c0d8f9661614a670437
https://doi.org/10.1007/s00204-022-03388-x
https://doi.org/10.1007/s00204-022-03388-x
Autor:
Marieke van der Zwan, MD, Carla C. Baan, PhD, Robert B. Colvin, MD, PhD, Rex N. Smith, MD, PhD, Rebecca A. White, Dorothy Ndishabandi, Alex L. Nigg, Thierry P.P. van den Bosch, PhD, Gretchen N. de Graav, MD, PhD, Marian C. Clahsen-van Groningen, MD, PhD, Dennis A. Hesselink, MD, PhD
Publikováno v:
Transplantation Direct, Vol 5, Iss 1, p e418 (2019)
Background. Belatacept-based therapy in kidney transplant recipient has been shown to increase long-term renal allograft and patient survival compared with calcineurin inhibitor–based therapy, however, with an increased risk of acute T cell-mediate
Externí odkaz:
https://doaj.org/article/932b155d9b794b31a623b1ecca59389a