Zobrazeno 1 - 10 of 228 pro vyhledávání: '"Robert A. Coburn"'
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Elektronická kniha
Religious Language, Meaning, and Use : The God Who Is Not There
Autor: Robert K. Bolger, Robert C. Coburn
Can the meaning of religious language be separated from its use? In Religious Language, Meaning, and Use, Robert Bolger and Robert Coburn address what has become a contentious though often overlooked account of the relationship between religious beli
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Effects of New 4-Aryl-1,4-Dihydropyridines and 4-Arylpyridines on Drug Efflux Mediated by Multidrug Resistance-Associated Protein 1
Autor: Marilyn E. Morris, Robert A. Coburn, Xiao-fei Zhou
Publikováno v: Journal of Pharmaceutical Sciences. 94:2256-2265
The purpose of this study is to evaluate the effects of newly synthesized 4-aryl-1,4-dihydropyridine and pyridines on drug efflux mediated by multidrug resistance-associated protein 1 (MRP1, ABCC1). These compounds were designed to maximize inhibitio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6056e21c5b39f982596d8a3b26d4d5
https://doi.org/10.1002/jps.20406
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6
Quantitative Structure–Activity Relationship and Quantitative Structure–Pharmacokinetics Relationship of 1,4-Dihydropyridines and Pyridines as Multidrug Resistance Modulators
Autor: Xiao-fei Zhou, Marilyn E. Morris, Robert A. Coburn, Qingxiang Shao
Publikováno v: Pharmaceutical Research. 22:1989-1996
The aim of this study was to develop quantitative structure–activity/pharmacokinetic relationships (QSAR/QSPKR) for a series of synthesized 1,4-dihydropyridines (DHPs) and pyridines as P-glycoprotein (P-gp) inhibitors. Molecular descriptors of test
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc1a732425890b1d4eb195cb2cb2ccc0
https://doi.org/10.1007/s11095-005-8112-0
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7
Structure activity relationships and quantitative structure activity relationships for the flavonoid-mediated inhibition of breast cancer resistance protein
Autor: Robert A. Coburn, Marilyn E. Morris, Xinning Yang, Shuzhong Zhang
Publikováno v: Biochemical Pharmacology. 70:627-639
Breast cancer resistance protein (BCRP) is a newly identified ABC transporter, which plays an important role in drug disposition and represents an additional mechanism for the development of MDR. Flavonoids, a major class of natural compounds widely
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b063c89ef932f27d1572483c740dd2
https://doi.org/10.1016/j.bcp.2005.05.017
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