Zobrazeno 1 - 10
of 7 357
pro vyhledávání: '"Robert A. Brown"'
Autor:
Alok Kumar, Robert A. Brown, Daniel Benyamien Roufaeil, Aditi Gupta, Erika L. Lipford, Divya Muthusamy, Amihai Zalzman, Ronna Hertzano, Tao Lowe, Joseph P. Stains, Michal Zalzman
Publikováno v:
Advanced Science, Vol 11, Iss 11, Pp n/a-n/a (2024)
Abstract 3D bioprinting holds great promise for meeting the increasing need for transplantable tissues and organs. However, slow printing, interlayer mixing, and the extended exposure of cells to non‐physiological conditions in thick structures sti
Externí odkaz:
https://doaj.org/article/89d7e680e9284e81895ba0edb997174b
Autor:
W. Alex Meltzer, Aditi Gupta, Phyo Nay Lin, Robert A. Brown, Daniel S. Benyamien-Roufaeil, Raju Khatri, Anup A. Mahurkar, Yang Song, Rodney J. Taylor, Michal Zalzman
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3898 (2024)
Cancers harness embryonic programs to evade aging and promote survival. Normally, sequences at chromosome ends called telomeres shorten with cell division, serving as a countdown clock to limit cell replication. Therefore, a crucial aspect of cancero
Externí odkaz:
https://doaj.org/article/295d5f4d078c4d8f8387394b24f0231f
Autor:
Lena Landaverde, David McIntyre, James Robson, Dany Fu, Luis Ortiz, Rita Chen, Samuel M.D. Oliveira, Andy Fan, Amy Barrett, Stephen P. Burgay, Stephen Choate, David Corbett, Lynn Doucette-Stamm, Kevin Gonzales, Davidson H. Hamer, Lilly Huang, Shari Huval, Christopher Knight, Carrie Landa, Diane Lindquist, Kelly Lockard, Trevor L. Macdowell, Elizabeth Mauro, Colleen McGinty, Candice Miller, Maura Monahan, Randall Moore, Judy Platt, Lloyd Rolles, Jeffrey Roy, Tracey Schroeder, Dean R. Tolan, Ann Zaia, Robert A. Brown, Gloria Waters, Douglas Densmore, Catherine M. Klapperich
Publikováno v:
SLAS Technology, Vol 27, Iss 5, Pp 302-311 (2022)
In 2019, the first cases of SARS-CoV-2 were detected in Wuhan, China, and by early 2020 the first cases were identified in the United States. SARS-CoV-2 infections increased in the US causing many states to implement stay-at-home orders and additiona
Externí odkaz:
https://doaj.org/article/a283dd9cabb6453bb4e35fac014e5ef7
Publikováno v:
Cellular & Molecular Biology Letters, Vol 26, Iss 1, Pp 1-18 (2021)
Abstract Background Neurological disorders are considered one of the greatest burdens to global public health and a leading cause of death. Stem cell therapies hold great promise for the cure of neurological disorders, as stem cells can serve as cell
Externí odkaz:
https://doaj.org/article/8a3498e33a264ed5bb08bddb0b45d870
Autor:
Robert A. Brown, Dumitru Fetco, Robert Fratila, Giulia Fadda, Shangge Jiang, Nuha M. Alkhawajah, E. Ann Yeh, Brenda Banwell, Amit Bar-Or, Douglas L. Arnold
Publikováno v:
NeuroImage, Vol 208, Iss , Pp 116442- (2020)
In conventional non-quantitative magnetic resonance imaging, image contrast is consistent within images, but absolute intensity can vary arbitrarily between scans. For quantitative analysis of intensity data, images are typically normalized to a cons
Externí odkaz:
https://doaj.org/article/bd63a9ce2d2f43e9a4159f49e42479c1
Autor:
Ola Awad, Leelamma M. Panicker, Rania M. Deranieh, Manasa P. Srikanth, Robert A. Brown, Antanina Voit, Tejasvi Peesay, Tea Soon Park, Elias T. Zambidis, Ricardo A. Feldman
Publikováno v:
Stem Cell Reports, Vol 9, Iss 6, Pp 1853-1867 (2017)
Summary: Gaucherâs disease (GD) is an autosomal recessive disorder caused by mutations in the GBA1 gene, which encodes acid β-glucocerebrosidase (GCase). Severe GBA1 mutations cause neuropathology that manifests soon after birth, suggesting that
Externí odkaz:
https://doaj.org/article/b566094708174a4a9b8d13faa014a0f1
Autor:
Julia C. Nantes, Sébastien Proulx, Jidan Zhong, Scott A. Holmes, Sridar Narayanan, Robert A. Brown, Richard D. Hoge, Lisa Koski
Publikováno v:
NeuroImage, Vol 157, Iss , Pp 705-715 (2017)
Converging areas of research have implicated glutamate and γ-aminobutyric acid (GABA) as key players in neuronal signalling and other central functions. Further research is needed, however, to identify microstructural and behavioral links to regiona
Externí odkaz:
https://doaj.org/article/a5cdf455780b4132b8af825f4a406775
Autor:
Robert A. Brown, Antanina Voit, Manasa P. Srikanth, Julia A. Thayer, Tami J. Kingsbury, Marlene A. Jacobson, Marta M. Lipinski, Ricardo A. Feldman, Ola Awad
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 10 (2019)
Bi-allelic GBA1 mutations cause Gaucher's disease (GD), the most common lysosomal storage disorder. Neuronopathic manifestations in GD include neurodegeneration, which can be severe and rapidly progressive. GBA1 mutations are also the most frequent g
Externí odkaz:
https://doaj.org/article/071ad8f2001a470988d9369dd1d74923
Publikováno v:
NeuroImage: Clinical, Vol 6, Iss C, Pp 20-25 (2014)
Multiple sclerosis (MS) is characterized by the formation of demyelinating lesions in the white matter (WM). However, the timecourse of the evolution of healthy white matter into fully demyelinated lesions in MS is not well understood. We use a recen
Externí odkaz:
https://doaj.org/article/697da739298d4b29a8588277f67b88f6
Publikováno v:
NeuroImage: Clinical, Vol 6, Iss C, Pp 237-242 (2014)
Children and adolescents diagnosed with multiple sclerosis rarely accrue physical disability early in their disease. This could be explained by greater remyelination in children, a capacity that may be lost in adolescence or early adulthood. Magnetiz
Externí odkaz:
https://doaj.org/article/7f5c2247adb44cbeaf697461cc7e859f