Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Robert A. Briddell"'
Autor:
Robert A. Briddell, Ian K. McNiece
Publikováno v:
Experimental Hematology. 29:3-11
Hematopoietic cells have the potential for providing benefit in a variety of clinical settings. These include cells for support of patients undergoing high-dose chemotherapy, as a target for replacement gene therapy, and as a source of cells for immu
Publikováno v:
Journal of Hematotherapy. 7:457-461
Ex vivo expansion of cord blood (CB) cells requires CD34+ cell selection before expansion to obtain optimal numbers of progenitor cells. As a preliminary step to preclinical development of CB expansion, we have evaluated two clinical scale selection
Autor:
Roy B. Jones, L. Chap, Ian McNiece, Elizabeth J. Shpall, William P. Sheridan, Michael Lill, C. F. LeMaistre, S. A. Turner, John A. Glaspy, M. D. Wiers, Dora Menchaca, Robert A. Briddell
Publikováno v:
Blood. 90:2939-2951
The safety and optimal dose and schedule of stem cell factor (SCF ) administered in combination with filgrastim for the mobilization of peripheral blood progenitor cells (PBPCs) was determined in 215 patients with high-risk breast cancer. Patients re
Autor:
Stefan Miltenyi, G Stoney, K. Zilm, Robert A. Briddell, Diether J. Recktenwald, Ian K. McNiece, Brent Kern
Publikováno v:
Journal of Hematotherapy. 6:5-11
The Amgen Cell Selection Device (ACSD) is a fully automated system based on the research scale magnetic-activated cell separation (MACS) system (Miltenyi Biotech GmbH, Bergisch Gladbach, Germany) for the selection of CD34+ cells. Leukapheresis produc
Autor:
Frederick R. Appelbaum, Glenn H. Knitter, Ian McNiece, Robert G. Andrews, Scott D. Rowley, Robert A. Briddell
Publikováno v:
Blood. 85:15-20
We have previously shown that administration of low-dose recombinant human stem cell factor (rhSCF) plus recombinant human granulocyte colony-stimulating factor (rhG-CSF) to baboons mobilizes greater numbers of progenitor cells in the blood than does
Autor:
Melissa Bronsden, Frederick R. Appelbaum, David Myerson, Tim Opie, Glenn H. Knitter, Robert A. Briddell, Robert G. Andrews, Ian McNiece
Publikováno v:
Blood. 84:800-810
Recombinant human stem cell factor (rhSCF) and recombinant human granulocyte colony-stimulating factor (rhG-CSF) are synergistic in vitro in stimulating the proliferation of hematopoietic progenitor cells and their precursors. We examined the in vivo
Publikováno v:
Blood. 84:795-799
In this study, we have compared the ability of recombinant human granulocyte colony-stimulating factor (rhG-CSF) alone and the combination of low doses of recombinant rat pegylated stem cell factor (rrSCF-PEG) plus rhG-CSF to mobilize peripheral bloo
Publikováno v:
Stem Cells. 11:83-88
The use of cytokine mobilized peripheral blood progenitor cells (PBPC) in transplantation following chemotherapy has led to enhanced engraftment. Granulocyte-colony stimulating factor (G-CSF) has been shown in a number of clinical studies to be an ef
Publikováno v:
Blood. 82:1720-1723
Splenectomized mice treated for 7 days with pegylated recombinant rat stem cell factor (rrSCF-PEG) showed a dose-dependent increase in peripheral blood progenitor cells (PBPC) that have enhanced in vivo repopulating potential. A dose of rrSCF-PEG at
Autor:
Ronald Hoffman, Edward F. Srour, Tom Leemhuis, Robert A. Briddell, Susan Grigsby, John E. Brandt
Publikováno v:
Blood. 81:661-669
Although sustained production of committed human hematopoietic progenitor cells in long-term bone marrow cultures (LTBMC) is well documented, evidence for the generation and expansion of human primitive hematopoietic progenitor cells (PHPC) in such c