Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Robert A. Ahokas"'
Publikováno v:
Placenta. 36:1450-1454
Introduction To assess the effects of selective reduced uterine perfusion pressure (SRUPP) in pregnant rats. Methods 20 pregnant Sprague–Dawley rats were allocated either to an intervention group, exposed to SRUPP (n = 10) or a control group, expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db6650db225a5cc8f8e9f5650e00e93
https://doi.org/10.1016/j.placenta.2015.10.017
https://doi.org/10.1016/j.placenta.2015.10.017
Autor:
Wenyuan Zhao, Weixin Meng, Robert A. Ahokas, Yuanjian Chen, Chang Liu, Hongyu Liu, Tieqiang Zhao, Yao Sun
Publikováno v:
Molecular and Cellular Biochemistry. 397:295-304
Cardiac repair and remodeling occur following myocardial infarction (MI). Our previous study demonstrated that platelet-derived growth factor (PDGF)-A/-D and PDGF receptors (PDGFR) are increased in the infarcted heart, with cells expressing PDGFR pri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6774f0bd7b228e8a1fab33c96bdcfdb
https://doi.org/10.1007/s11010-014-2197-x
https://doi.org/10.1007/s11010-014-2197-x
Autor:
Robert A. Ahokas, Wenyuan Zhao, M. Usman Khan, Ivan C. Gerling, Fahed Al Darazi, Tieqiang Zhao, Yao Sun, Syamal K. Bhattacharya, Karl T. Weber
Publikováno v:
Journal of Cardiovascular Pharmacology. 62:445-451
Cardiomyocyte necrosis with attendant microscopic scarring is a pathological feature of human hypertensive heart disease (HHD). Understanding the pathophysiological origins of necrosis is integral to its prevention. In a rat model of HHD associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64497704f6223ccfd34b1a96c8b735de
https://doi.org/10.1097/fjc.0b013e3182a0b5ff
https://doi.org/10.1097/fjc.0b013e3182a0b5ff
Publikováno v:
Nature Reviews Cardiology. 10:15-26
The syncytium of cardiomyocytes in the heart is tethered within a matrix composed principally of type I fibrillar collagen. The matrix has diverse mechanical functions that ensure the optimal contractile efficiency of this muscular pump. In the disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af4a5a29b5dfcd7b3a81e5493f7cd26
https://doi.org/10.1038/nrcardio.2012.158
https://doi.org/10.1038/nrcardio.2012.158
Autor:
M. Usman Khan, Ivan C. Gerling, Kelly D. Green, Tieqiang Zhao, Karl T. Weber, Robert A. Ahokas, Syamal K. Bhattacharya, Wenyuan Zhao, Yaser Cheema
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 303:H486-H495
The congestive heart failure (CHF) syndrome with soft tissue wasting, or cachexia, has its pathophysiologic origins rooted in neurohormonal activation. Mechanical cardiocirculatory assistance reveals the potential for reverse remodeling and recovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d574deb4c03bfa8085099bd98724ca35
https://doi.org/10.1152/ajpheart.00192.2012
https://doi.org/10.1152/ajpheart.00192.2012
Publikováno v:
International Journal of Cardiology. 152:307-313
Acidic and basic fibroblast growth factors (FGF-1/FGF-2) promote angiogenesis in cancer. Angiogenesis is integral to cardiac repair following myocardial infarction (MI). The potential regulation of FGF-1/FGF-2 in cardiac angiogenesis postMI remains u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0c684508011848fbfe29cc7dee8d0e
https://doi.org/10.1016/j.ijcard.2010.07.024
https://doi.org/10.1016/j.ijcard.2010.07.024
Autor:
Yaser Cheema, Karl T. Weber, Robert A. Ahokas, Yao Sun, Ivan C. Gerling, Syamal K. Bhattacharya, Jonathan N Sherrod, Tieqiang Zhao, Wenyuan Zhao
Publikováno v:
Journal of Cardiovascular Pharmacology. 58:80-86
Foci of fibrosis, footprints of cardiomyocyte necrosis, are scattered throughout the failing myocardium and are a major component to its pathologic remodeling. Understanding pathogenic mechanisms contributing to hormone-mediated necrosis is therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104cb5146063285a695966e490bd3e72
https://doi.org/10.1097/fjc.0b013e31821cd83c
https://doi.org/10.1097/fjc.0b013e31821cd83c
Autor:
Syamal K. Bhattacharya, Atta U. Shahbaz, Karl T. Weber, Patti L. Johnson, Ivan C. Gerling, Wenyuan Zhao, Robert A. Ahokas, Tieqiang Zhao, Yao Sun
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 300:H636-H644
Acute hyperadrenergic stressor states are accompanied by cation dyshomeostasis, together with the release of cardiac troponins predictive of necrosis. The signal-transducer-effector pathway accounting for this pathophysiological scenario remains uncl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c77f843e1044bf38c9c269bf1b89c6a
https://doi.org/10.1152/ajpheart.00900.2010
https://doi.org/10.1152/ajpheart.00900.2010
Autor:
Patti L. Johnson, Atta U. Shahbaz, Syamal K. Bhattacharya, Robert A. Ahokas, Karl T. Weber, Ivan C. Gerling, Tieqiang Zhao, Yao Sun, Wenyuan Zhao, German Kamalov
Publikováno v:
Journal of Cardiovascular Pharmacology. 57:37-43
Chronic aldosterone/salt treatment (ALDOST) is accompanied by an adverse structural remodeling of myocardium that includes multiple foci of microscopic scarring representing morphologic footprints of cardiomyocyte necrosis. Our previous studies sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adbb181a50736d754147e12abcc01723
https://doi.org/10.1097/fjc.0b013e3181fe1250
https://doi.org/10.1097/fjc.0b013e3181fe1250
Autor:
Ivan C. Gerling, Robert A. Ahokas, Jesse E. McGee, Karl T. Weber, Atta U. Shahbaz, Yao Sun, Syamal K. Bhattacharya
Publikováno v:
Journal of Hypertension. 28:S25-S32
Fibrosis is a fundamental component of the adverse structural remodelling of myocardium found in hypertensive heart disease (HHD). A replacement fibrosis appears at sites of previous cardiomyocyte necrosis to preserve the structural integrity of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1839ecae2756204a78afb170f3723082
https://doi.org/10.1097/01.hjh.0000388491.35836.d2
https://doi.org/10.1097/01.hjh.0000388491.35836.d2