Docetaxel and gemcitabine combination therapy in advanced transitional cell carcinoma of the urothelium: results of a phase II and pharmacologic study

Autor: Ernst A. de Bruijn, Gunter Guetens, Allan T. van Oosterom, Marc Martens, Robert A. A. Maes, J. Selleslach, Rita Aerts, Herlinde Dumez, Gert De Boeck

Publikováno v: Anti-Cancer Drugs. 18:211-218

Our objective was to determine the response to gemcitabine plus docetaxel in advanced urothelial transitional cell carcinoma in a phase II trial, and gemcitabine distribution between plasma and erythrocytes, following docetaxel administration. Patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e552895900c9fd03c72a6a7849d92696
https://doi.org/10.1097/cad.0b013e328010ee5c

Amount of self-reported illicit drug use compared to quantitative hair test results in community-recruited young drug users in Amsterdam

Autor: Esther A. E. Welp, Ingrid J Bosman, Maja Totté, Miranda W. Langendam, Robert A. A. Maes, Erik van Ameijden

Publikováno v: Addiction. 98:987-994

Aims To assess the dose–effect relationship between self-reported drug intake and the concentration of drugs and/or their metabolites in hair and to examine factors that may mediate this relationship. Design and setting A cohort study among young d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f2eca609ec8be4c69720b3672c87344
https://doi.org/10.1046/j.1360-0443.2003.00421.x

Operant learning and differential-reinforcement-of-low-rate 36-s responding in 5-HT1A and 5-HT1B receptor knockout mice

Autor: Laus M. Broersen, Lucianne Groenink, Tommy Pattij, Jan van der Gugten, Robert A. A. Maes, Berend Olivier, Judith van der Linde

Publikováno v: Behavioural Brain Research, 141, 137-45
Behavioural Brain Research, 141(2), 137-145. Elsevier
Behavioural Brain Research, 141, 2, pp. 137-45
Pattij, T, Broersen, L M, Van der Linde, J, Groenink, L, Van der Gugten, J, Maes, R A A & Olivier, B 2003, ' Operant learning and differential-reinforcement-of-low-rate 36-s responding in 5-HT 1A and 5-HT 1B receptor knockout mice ', Behavioural Brain Research, vol. 141, no. 2, pp. 137-145 . https://doi.org/10.1016/S0166-4328(02)00345-5

Previous studies with mice lacking 5-HT1A (1AKO) and 5-HT1B (1BKO) receptors in hippocampus-dependent learning and memory paradigms, suggest that these receptors play an important role in learning and memory, although their precise role is unclear. I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6435eb9c78933e937fceeb6f8fc89f7a
https://hdl.handle.net/2066/119647

Autonomic changes associated with enhanced anxiety in 5-ht1a receptor knockout mice

Autor: Lucianne Groenink, Jan van der Gugten, Theo H. Hijzen, Berend Olivier, Robert A. A. Maes, Ronald S. Oosting, Tommy Pattij

Publikováno v: Pattij, T, Groenink, L, Hijzen, T H, Oosting, R S, Maes, R A A, Van der Gugten, J & Olivier, B 2002, ' Autonomic changes associated with enhanced anxiety in 5-ht 1a receptor knockout mice ', Neuropsychopharmacology, vol. 27, no. 3, pp. 380-390 . https://doi.org/10.1016/S0893-133X(02)00317-2
Neuropsychopharmacology, 27, 380-90
Neuropsychopharmacology, 27, 3, pp. 380-90
Neuropsychopharmacology, 27(3), 380-390. Nature Publishing Group

5-HT1A receptor knockout (KO) mice have been described as more anxious in various anxiety paradigms. Because anxiety is often associated with autonomic changes like elevated body temperature and tachycardia, radiotelemetry was used to study these par

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991593731857c675f29c3461ac0a3f78
https://doi.org/10.1016/s0893-133x(02)00317-2

Piperazine-like compounds: a new group of designer drugs-of-abuse on the European market

Autor: András A Benkö, Lourenço J.A.L dos Reys, D. de Boer, Carmo Manzoni, Elöd Hidvégi, Robert A. A. Maes, Ingrid J Bosman

Publikováno v: Forensic Science International. 121:47-56

1-Aryl-piperazine compounds are, depending on their substituents, selective for certain serotonin receptors and together with their easy availability and their so-called legal status, this group of psychoactive compounds are potential designer drugs-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460e5933ac7abc2bcfa54c86b9075b13
https://doi.org/10.1016/s0379-0738(01)00452-2