Zobrazeno 1 - 10
of 527
pro vyhledávání: '"Robert A Stockley"'
Publikováno v:
Annals of Thoracic Medicine, Vol 15, Iss 2, Pp 54-63 (2020)
Chronic obstructive pulmonary disease (COPD) is common and debilitating. Most patients with COPD experience intermittent, acute deterioration in symptoms which require additional therapy, termed exacerbations. Exacerbations are prevalent in COPD and
Externí odkaz:
https://doaj.org/article/c5477564c4d04c888c26e4f564884965
Autor:
Peymané Adab, Rachel E Jordan, David Fitzmaurice, Jon G Ayres, KK Cheng, Brendan G Cooper, Amanda Daley, Andrew Dickens, Alexandra Enocson, Sheila Greenfield, Shamil Haroon, Kate Jolly, Sue Jowett, Tosin Lambe, James Martin, Martin R Miller, Kiran Rai, Richard D Riley, Steve Sadhra, Alice Sitch, Stanley Siebert, Robert A Stockley, Alice Turner
Publikováno v:
Programme Grants for Applied Research, Vol 9, Iss 13 (2021)
Background: Chronic obstructive pulmonary disease is a major contributor to morbidity, mortality and health service costs but is vastly underdiagnosed. Evidence on screening and how best to approach this is not clear. There are also uncertainties aro
Externí odkaz:
https://doaj.org/article/d5823b1af06247dbbff28d73cde2a65d
Publikováno v:
BMJ Open, Vol 10, Iss 6 (2020)
Objectives To establish a database network for the study of alpha-1 antitrypsin deficiency (AATD) and compare the results to CT lung density as the most direct measure of emphysema.Design A central electronic database was established to permit the up
Externí odkaz:
https://doaj.org/article/e3ed8d609ca4427c9bf1da3d59571613
Autor:
Robert A. Stockley, David G. Parr
Publikováno v:
ERJ Open Research, Vol 10, Iss 4 (2024)
The past 60 years have seen multiple publications related to lung disease in α1-antitrypsin deficiency largely reflecting the pathophysiology, biochemical effect and outcomes of augmentation therapy. However, the complexity of disease phenotype and
Externí odkaz:
https://doaj.org/article/5a88707c761e4231b050c16747a2b402
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Alpha-1 antitrypsin deficiency (AATD) is a genetic condition resulting from mutations in the alpha-1 antitrypsin (AAT) protein, a major systemic antiproteinase, resulting in reduced/no release of AAT, disrupting the proteinase/antiprotein
Externí odkaz:
https://doaj.org/article/6f4233b5a72a4d90af2cf6faacf8a454
Autor:
Chirag Dave, Simon Wharton, Rahul Mukherjee, Bandar M. Faqihi, Robert A. Stockley, Alice M. Turner
Publikováno v:
Canadian Respiratory Journal, Vol 2021 (2021)
Background. Identification of patients who may become hypercapnic, or develop acidotic hypercapnic respiratory failure (AHRF), is important in chronic obstructive pulmonary disease (COPD) to avoid hospital admission and select patients for use of hom
Externí odkaz:
https://doaj.org/article/8d54e9b530e14eafbc84a856bc1f8f54
Autor:
Paul R. Ellis, Kristen E. Holm, Radmila Choate, David M. Mannino, Robert A. Stockley, Robert A. Sandhaus, Alice M. Turner
Publikováno v:
Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation. 10:139-147
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-10 (2018)
Abstract Chronic Obstructive Pulmonary Disease (COPD) is a common, multifactorial lung disease which results in significant impairment of patients’ health and a large impact on society and health care burden. It is believed to be the result of prol
Externí odkaz:
https://doaj.org/article/729978e06f274551851ff9ab8981e6cb
Background Although bronchiectasis has been recognised as a feature of some patients with Alpha1-Antitrypsin deficiency the prevalence and characteristics are not widely known. We wished to determine the prevalence of bronchiectasis and patient chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e63b5f97199eaf9e9d6b9ee0b26e12d
https://doi.org/10.21203/rs.3.rs-2612082/v1
https://doi.org/10.21203/rs.3.rs-2612082/v1
Autor:
Robert A. STOCKLEY
Publikováno v:
Minerva Respiratory Medicine. 62