Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Robert A Rissman"'
Autor:
Chelsea C Hays Weeks, Alison A Moore, Matthew Allison, Kevin Patrick, Mark W Bondi, Camille Nebeker, Thomas T Liu, David Wing, Michael Higgins, Sheri J Hartman, Robert A Rissman, Zvinka Z Zlatar
Publikováno v:
JMIR Research Protocols, Vol 12, p e42980 (2023)
BackgroundExtensive research suggests that physical activity (PA) is important for brain and cognitive health and may help to delay or prevent Alzheimer's disease and related dementias. Most PA interventions designed to improve brain health in older
Externí odkaz:
https://doaj.org/article/2c45df82c3994dd2b4868c16b6539a1d
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0251611 (2021)
Alternative splicing of the gene MAPT produces several isoforms of tau protein. Overexpression of these isoforms is characteristic of tauopathies, which are currently untreatable neurodegenerative diseases. Though non-canonical functions of tau have
Externí odkaz:
https://doaj.org/article/2db5286bb3dd42cc89e687069b57ad7b
Autor:
Cheng Zhang, Robert A Rissman
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181367 (2017)
Increased production of hydroxyl radical is the main source of oxidative damage in mammalian DNA that accumulates in Alzheimer's disease (AD). Reactive oxygen species (ROS) react with both nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) to generate
Externí odkaz:
https://doaj.org/article/7e61b1ae710641a39d781839b059553c
Autor:
Michelle H Le, April M Weissmiller, Louise Monte, Po Han Lin, Tia C Hexom, Orlangie Natera, Chengbiao Wu, Robert A Rissman
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147250 (2016)
Stress exposure or increased levels of corticotropin-releasing factor (CRF) induce hippocampal tau phosphorylation (tau-P) in rodent models, a process that is dependent on the type-1 CRF receptor (CRFR1). Although these preclinical studies on stress-
Externí odkaz:
https://doaj.org/article/12c5997d44334087b2c839abeee24465
Autor:
Amanda J Mishizen-Eberz, Robert A Rissman, Troy L Carter, Milos D Ikonomovic, Barry B Wolfe, David M Armstrong
Publikováno v:
Neurobiology of Disease, Vol 15, Iss 1, Pp 80-92 (2004)
Alzheimer's disease (AD) is characterized by loss of specific cell populations within selective subregions of the hippocampus. Excitotoxicity, mediated via ionotropic glutamate receptors, may play a crucial role in this selective neuronal vulnerabili
Externí odkaz:
https://doaj.org/article/151866f5834a46b19a1cc1c6906f0b1d
Autor:
Brian Spencer, Ivy Trinh, Edward Rockenstein, Michael Mante, Jazmin Florio, Anthony Adame, Omar M.A. El-Agnaf, Changyoun Kim, Eliezer Masliah, Robert A. Rissman
Publikováno v:
Neurobiology of Disease, Vol 191, Iss , Pp 106397- (2024)
Externí odkaz:
https://doaj.org/article/73d77c89544648b3b03a844465b7f0f9
Autor:
Maria Čarna, Jan S. Novotny, Neda Dragišić, Hanuš Slavik, Kateřina Sheardova, Yonas E. Geda, Martin Vyhnalek, Jan Laczo, Jakub Hort, Zixu Mao, Robert A. Rissman, Marian Hajduch, Eric B. Dammer, Gorazd B. Stokin
Publikováno v:
Journal of Neurochemistry. 165:149-161
Autor:
Charisse N. Winston, Oliver Langford, Natalie Levin, Rema Raman, Kevin Yarasheski, Tim West, Sara Abdel-Latif, Michael Donohue, Akinori Nakamura, Kenji Toba, Colin L. Masters, James Doecke, Reisa A. Sperling, Paul S. Aisen, Robert A. Rissman
Publikováno v:
Journal of Alzheimer's Disease. 92:95-107
Background: Participant eligibility for the A4 Study was determined by amyloid PET imaging. Given the disadvantages of amyloid PET imaging in accessibility and cost, blood-based biomarkers may serve as a sufficient biomarker and more cost-effective s
Autor:
Emily Z, Huie, Anthony, Escudero, Naomi, Saito, Danielle, Harvey, My-Le, Nguyen, Katherine L, Lucot, Jayne, LaGrande, Dan, Mungas, Charles, DeCarli, Melissa, Lamar, Julie A, Schneider, Alifiya, Kapasi, Robert A, Rissman, Andrew F, Teich, Brittany N, Dugger
Publikováno v:
Journal of Alzheimer's Disease. 91:1291-1301
Background: Transactive Response DNA Binding Protein 43 kDa (TDP-43) pathology is frequently found in cases with Alzheimer’s disease (AD). TDP-43 pathology is associated with hippocampal atrophy and greater AD severity denoted by cognition and clin
Autor:
Aloke K. Dutta, Christopher Armstrong, Dan Luo, Banibrata Das, Brian Spencer, Robert A. Rissman
Publikováno v:
ACS Chemical Neuroscience. 14:885-896