Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Robert A Policastro"'
Autor:
Michael D Rotelli, Robert A Policastro, Anna M Bolling, Andrew W Killion, Abraham J Weinberg, Michael J Dixon, Gabriel E Zentner, Claire E Walczak, Mary A Lilly, Brian R Calvi
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008253 (2019)
Endoreplication is a cell cycle variant that entails cell growth and periodic genome duplication without cell division, and results in large, polyploid cells. Cells switch from mitotic cycles to endoreplication cycles during development, and also in
Externí odkaz:
https://doaj.org/article/9b03fb4650ca4d9a83cd8d323520dde5
Autor:
Nader H. Mahmoudzadeh, Yasaman Heidarian, Jason P. Tourigny, Alexander J. Fitt, Katherine Beebe, Hongde Li, Arthur Luhur, Kasun Buddika, Liam Mungcal, Anirban Kundu, Robert A. Policastro, Garrett J. Brinkley, Gabriel E. Zentner, Travis Nemkov, Robert Pepin, Geetanjali Chawla, Sunil Sudarshan, Aylin R. Rodan, Angelo D'Alessandro, Jason M. Tennessen
Publikováno v:
Molecular Metabolism, Vol 89, Iss , Pp 102013- (2024)
Objectives: The mitochondrial enzyme L-2-hydroxyglutarate dehydrogenase (L2HGDH) regulates the abundance of L-2-hydroxyglutarate (L-2HG), a potent signaling metabolite capable of influencing chromatin architecture, mitochondrial metabolism, and cell
Externí odkaz:
https://doaj.org/article/c959551a1a6c44d4a4238d794febab0c
Autor:
Heather M. O'Hagan, Gabriel E. Zentner, Philip A. Cole, Jay H. Kalin, Sha Cao, Helai P. Mohammad, Xiaoyu Lu, Ning Ding, Shruthi Sriramkumar, Sudha S. Savant, Robert A. Policastro, Samuel A. Miller
Supplementary Table S1: Mutational status of common oncogenes in CRC and STAD cell lines. Supplementary Figure S1: Mutant PIK3CA does not regulate LSD1 expression. Supplementary Figure S2: DNase signal is not generally depleted at TSS's, and LSD1 doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f941c62abdac958080c3361122a6fbc
https://doi.org/10.1158/1541-7786.22516900
https://doi.org/10.1158/1541-7786.22516900
Autor:
Heather M. O'Hagan, Gabriel E. Zentner, Philip A. Cole, Jay H. Kalin, Sha Cao, Helai P. Mohammad, Xiaoyu Lu, Ning Ding, Shruthi Sriramkumar, Sudha S. Savant, Robert A. Policastro, Samuel A. Miller
Activation of the epithelial-to-mesenchymal transition (EMT) program is a critical mechanism for initiating cancer progression and migration. Colorectal cancers contain many genetic and epigenetic alterations that can contribute to EMT. Mutations act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7928fb146a73ac07f46fae05ff391c9
https://doi.org/10.1158/1541-7786.c.6541534
https://doi.org/10.1158/1541-7786.c.6541534
Autor:
Heather M. O'Hagan, Gabriel E. Zentner, Philip A. Cole, Jay H. Kalin, Sha Cao, Helai P. Mohammad, Xiaoyu Lu, Ning Ding, Shruthi Sriramkumar, Sudha S. Savant, Robert A. Policastro, Samuel A. Miller
Contains additional details on bioinformatic analyses, including references for packages used.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51cb38ed036f5434726ca66bad678e4a
https://doi.org/10.1158/1541-7786.22516897.v1
https://doi.org/10.1158/1541-7786.22516897.v1
Autor:
Heather M. O'Hagan, Gabriel E. Zentner, Chunhai Hao, Daeho Kim, Christopher A. Ladaika, Thomas D. Huntington, Tim Lai, Shruthi Sriramkumar, Robert A. Policastro, Samuel A. Miller
Statistical analysis of TCGA COAD comparing Normal, BRAF mutant, KRAS mutant, and all other tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af9f2d2a5b6bce3f9714dbe2c37c2de
https://doi.org/10.1158/0008-5472.22428906.v1
https://doi.org/10.1158/0008-5472.22428906.v1
Autor:
Heather M. O'Hagan, Gabriel E. Zentner, Chunhai Hao, Daeho Kim, Christopher A. Ladaika, Thomas D. Huntington, Tim Lai, Shruthi Sriramkumar, Robert A. Policastro, Samuel A. Miller
Statistical analysis of pathological subtype enrichment in TCGA COAD BRAF mutant, KRAS mutant, and all other tumor groups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6d9b07f7c48966001dfbae689696ca
https://doi.org/10.1158/0008-5472.22428909.v1
https://doi.org/10.1158/0008-5472.22428909.v1
Autor:
Heather M. O'Hagan, Gabriel E. Zentner, Chunhai Hao, Daeho Kim, Christopher A. Ladaika, Thomas D. Huntington, Tim Lai, Shruthi Sriramkumar, Robert A. Policastro, Samuel A. Miller
Despite the connection of secretory cells, including goblet and enteroendocrine (EEC) cells, to distinct mucus-containing colorectal cancer histologic subtypes, their role in colorectal cancer progression has been underexplored. Here, our analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49c4ad2c1983e33f194a9ed0426c5a07
https://doi.org/10.1158/0008-5472.c.6513192.v1
https://doi.org/10.1158/0008-5472.c.6513192.v1
Autor:
Heather M. O'Hagan, Gabriel E. Zentner, Chunhai Hao, Daeho Kim, Christopher A. Ladaika, Thomas D. Huntington, Tim Lai, Shruthi Sriramkumar, Robert A. Policastro, Samuel A. Miller
Supplemental Tables 1 and 2, Supplemental Figures 1-8, Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787cb5d880298028e4385f2feb9734b9
https://doi.org/10.1158/0008-5472.22428918
https://doi.org/10.1158/0008-5472.22428918
Autor:
Heather M. O'Hagan, Gabriel E. Zentner, Chunhai Hao, Daeho Kim, Christopher A. Ladaika, Thomas D. Huntington, Tim Lai, Shruthi Sriramkumar, Robert A. Policastro, Samuel A. Miller
Statistical analysis of ATOH1 and MUC2 expression in TCGA COAD comparing Normal, BRAF mutant, KRAS mutant, and all other tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dfe57a1cc2bc5219b8bfa6713dcda9
https://doi.org/10.1158/0008-5472.22428912
https://doi.org/10.1158/0008-5472.22428912