Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Robert A McDougal"'
Autor:
Kammarauche Aneni, Ching-Hua Chen, Jenny Meyer, Youngsun T Cho, Zachary Chase Lipton, Saatvik Kher, Megan G Jiao, Isabella Gomati de la Vega, Feza Anaise Umutoni, Robert A McDougal, Lynn E Fiellin
Publikováno v:
JMIR Research Protocols, Vol 12, p e46990 (2023)
BackgroundAdolescents at risk for substance misuse are rarely identified early due to existing barriers to screening that include the lack of time and privacy in clinic settings. Games can be used for screening and thus mitigate these barriers. Perfo
Externí odkaz:
https://doaj.org/article/0cd3d18e0f354b6685f222c7263f5830
Autor:
Adam Newton, Craig Kelley, Amy Guo, Joy Wang, Sydney Zink, Marcello Distasio, Robert A Mcdougal, William Lytton
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S792- (2023)
Externí odkaz:
https://doaj.org/article/a739de162609477d84ead08d08e842af
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 10, p e1011548 (2023)
Biophysically detailed simulations of neuronal activity often rely on solving large systems of differential equations; in some models, these systems have tens of thousands of states per cell. Numerically solving these equations is computationally int
Externí odkaz:
https://doaj.org/article/4251744d92244499a0932143737763f0
Autor:
Samuel A Neymotin, Dylan S Daniels, Blake Caldwell, Robert A McDougal, Nicholas T Carnevale, Mainak Jas, Christopher I Moore, Michael L Hines, Matti Hämäläinen, Stephanie R Jones
Publikováno v:
eLife, Vol 9 (2020)
Magneto- and electro-encephalography (MEG/EEG) non-invasively record human brain activity with millisecond resolution providing reliable markers of healthy and disease states. Relating these macroscopic signals to underlying cellular- and circuit-lev
Externí odkaz:
https://doaj.org/article/e8b0e0e82062488c816b690cec9072e8
Autor:
Salvador Dura-Bernal, Benjamin A Suter, Padraig Gleeson, Matteo Cantarelli, Adrian Quintana, Facundo Rodriguez, David J Kedziora, George L Chadderdon, Cliff C Kerr, Samuel A Neymotin, Robert A McDougal, Michael Hines, Gordon MG Shepherd, William W Lytton
Publikováno v:
eLife, Vol 8 (2019)
Biophysical modeling of neuronal networks helps to integrate and interpret rapidly growing and disparate experimental datasets at multiple scales. The NetPyNE tool (www.netpyne.org) provides both programmatic and graphical interfaces to develop data-
Externí odkaz:
https://doaj.org/article/cb268b2386744416909b4dbb859285d1
Autor:
Robert A McDougal, Gordon M Shepherd
Publikováno v:
Frontiers in Neuroinformatics, Vol 9 (2015)
Neurons come in a wide variety of shapes and sizes. In a quest to understand this neuronal diversity, researchers have three-dimensionally traced tens of thousands of neurons; many of these tracings are freely available through online repositories li
Externí odkaz:
https://doaj.org/article/cd7aa0996a6e46ae8a3e9de40bd4d5ba
Autor:
Peng Yuan, Mengyang Zhang, Lei Tong, Thomas M. Morse, Robert A. McDougal, Hui Ding, Diane Chan, Yifei Cai, Jaime Grutzendler
Publikováno v:
Nature. 612:328-337
The precise mechanisms that lead to cognitive decline in Alzheimer’s disease are unknown. Here we identify amyloid-plaque-associated axonal spheroids as prominent contributors to neural network dysfunction. Using intravital calcium and voltage imag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96d00bdc5bdaf6e40150017755faee55
https://doi.org/10.1038/s41586-022-05491-6
https://doi.org/10.1038/s41586-022-05491-6
Biophysically detailed simulations attempting to reproduce neuronal activity often rely on solving large systems of differential equations; in some models, these systems have tens of thousands of states per cell. Numerically solving these equations i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c07a016be805d9244bd39c80675152f
https://doi.org/10.1101/2023.04.15.536945
https://doi.org/10.1101/2023.04.15.536945
Autor:
Kammarauche Aneni, Ching-Hua Chen, Jenny Meyer, Youngsun T. Cho, Zachary Chase Lipton, Saatvik Kher, Megan G. Jiao, Isabella Gomati de la Vega, Feza Umutoni, Robert A. McDougal, Lynn E. Fiellin
BACKGROUND Adolescents at risk for substance misuse are rarely identified early due to existing barriers to screening that include lack of time and privacy in clinic settings. Games, which can be delivered without need for trained personnel, can be u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d475e97529d71558c8ba59a16ed7962
https://doi.org/10.2196/preprints.46990
https://doi.org/10.2196/preprints.46990
Publikováno v:
Frontiers in Neuroinformatics. 16
Neuronal activity is the result of both the electrophysiology and chemophysiology. A neuron can be well represented for the purposes of electrophysiological simulation as a tree composed of connected cylinders. This representation is also apt for 1D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e0f338eab912e2522da42d453c4029
https://doi.org/10.3389/fninf.2022.847108
https://doi.org/10.3389/fninf.2022.847108