Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Robert A Hromas"'
Autor:
Shan Qi, Javier Mota, Siu-Hong Chan, Johanna Villarreal, Nan Dai, Shailee Arya, Robert A Hromas, Manjeet K Rao, Ivan R Corrêa Jr, Yogesh K Gupta
Publikováno v:
eLife, Vol 11 (2022)
Methyltransferase like-3 (METTL3) and METTL14 complex transfers a methyl group from S-adenosyl-L-methionine to N6 amino group of adenosine bases in RNA (m6A) and DNA (m6dA). Emerging evidence highlights a role of METTL3-METTL14 in the chromatin conte
Externí odkaz:
https://doaj.org/article/f4794168c2784b479a677f7a2e4a2a3c
Autor:
Yuehan Wu, Suk-Hee Lee, Elizabeth A Williamson, Brian L Reinert, Ju Hwan Cho, Fen Xia, Aruna Shanker Jaiswal, Gayathri Srinivasan, Bhavita Patel, Alexis Brantley, Daohong Zhou, Lijian Shao, Rupak Pathak, Martin Hauer-Jensen, Sudha Singh, Kimi Kong, Xaiohua Wu, Hyun-Suk Kim, Timothy Beissbarth, Jochen Gaedcke, Sandeep Burma, Jac A Nickoloff, Robert A Hromas
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005675 (2015)
Replication fork stalling and collapse is a major source of genome instability leading to neoplastic transformation or cell death. Such stressed replication forks can be conservatively repaired and restarted using homologous recombination (HR) or non
Externí odkaz:
https://doaj.org/article/95fc9886b9814bed88fac687edfe81e9
Autor:
Javier Mota, Shan Qi, Siu-Hong Chan, Johanna Villarreal, Nan Dai, Shailee Arya, Robert A Hromas, Manjeet K Rao, Ivan R Corrêa Jr, Yogesh K Gupta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af79273bba51048c2ff37f71031e585
https://doi.org/10.7554/elife.67150.sa2
https://doi.org/10.7554/elife.67150.sa2
Publikováno v:
Cancer Research. 82:5654-5654
Cancer is a multistep process where genomic and epigenomic alterations results in abnormal cellular proliferation and dissemination. This unregulated cellular proliferation can be interrupted through intervention therapy. One such strategy utilizes p
Autor:
Shan, Qi, Javier, Mota, Siu-Hong, Chan, Johanna, Villarreal, Nan, Dai, Shailee, Arya, Robert A, Hromas, Manjeet K, Rao, Ivan R, Corrêa, Yogesh K, Gupta
Publikováno v:
eLife. 11
Methyltransferase like-3 (METTL3) and METTL14 complex transfers a methyl group from
Autor:
Troy A. Gobbett, David W. George, David E. Finch, Jianzhao Shen, Gail H. Vance, Robert A. Hromas, Mark R. Kelley, Sin-Ho Jung, Lawrence H. Einhorn, Virginia C. Thurston, Thomas M. Ulbright, Richard S. Foster, Devan J. Heiber, Nyla A. Heerema, Heather C. Ramsey, Kent A. Robertson
Publikováno v:
Journal of Clinical Oncology. 21:113-122
Purpose: Analysis of patients with late relapse (LR) of germ cell tumor (GCT) with reports on clinical characteristics, outcomes, and molecular and cytogenetic features. Patients and Methods: Eighty-three patients evaluated at Indiana University from
Publikováno v:
Blood. 98:3562-3568
Chemokines are a large family of cytokines that direct normal leukocyte migration. They also have been implicated in leukocyte development and in the pathogenesis of many diseases. The CC chemokine CCL21, also known as Exodus-2, SLC, 6Ckine, and TCA4
Autor:
Vishwanath Gharpure, Edward F. Srour, Richard S. Neiman, Nyla A. Heerema, Lorraine Rubin, Rafat Abonour, Chao H. Lee, Attilio Orazi, Kenneth Cornetta, Robert A. Hromas, Timothy C. Greiner, Sharon Haskins
Publikováno v:
American Journal of Clinical Pathology. 107:419-429
Posttransplantation lymphoproliferative disorders (PT-LPDs) occurring in T-cell depleted (TCD) allogeneic bone marrow transplant recipients seem to be different from those that arise in solid organ recipients in their early development, the high inci
Autor:
Robert A. Hromas
We and others identified a human SET and transposase domain protein termed Metnase (also called SETMAR) that methylates histone H3, and promotes DNA double-strand break repair. We postulated that Metnase could improve decatenation in breast cancer ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::255edb6edc438f678a6340091ab46729
https://doi.org/10.21236/ada486688
https://doi.org/10.21236/ada486688
Autor:
Michael J, Robertson, David, Pelloso, Rafat, Abonour, Robert A, Hromas, Robert P, Nelson, Lisa, Wood, Kenneth, Cornetta
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 8(11)
To determine the safety, maximum tolerated dose,and biological effects of recombinant human IL-12 after autologous stem cell transplantation for cancer.Twelve patients with hematological malignancies (8 non-Hodgkin's lymphoma, 2 Hodgkin's disease, an