Zobrazeno 1 - 10
of 2 964
pro vyhledávání: '"Robert A Harris"'
Autor:
Yoon Seok Jung, Ji-Min Lee, Don-Kyu Kim, Yong-Soo Lee, Ki-Sun Kim, Yong-Hoon Kim, Jina Kim, Myung-Shik Lee, In-Kyu Lee, Seong Heon Kim, Sung Jin Cho, Won-Il Jeong, Chul-Ho Lee, Robert A Harris, Hueng-Sik Choi
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159425 (2016)
Fibroblast growth factor 21 (FGF21), a stress inducible hepatokine, is synthesized in the liver and plays important roles in glucose and lipid metabolism. However, the mechanism of hepatic cannabinoid type 1 (CB1) receptor-mediated induction of FGF21
Externí odkaz:
https://doaj.org/article/b7c1404ea020483ab50acf1a7d08f919
Autor:
Kwangsoo Kim, Jae Ho Jeong, Daejin Lim, Yeongjin Hong, Hyung-Ju Lim, Geun-Joong Kim, So-ra Shin, Je-Jung Lee, Misun Yun, Robert A Harris, Jung-Joon Min, Hyon E Choy
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss , Pp - (2015)
Bacteria can be engineered to deliver anticancer proteins to tumors via a controlled expression system that maximizes the concentration of the therapeutic agent in the tumor. L-asparaginase (L-ASNase), which primarily converts asparagine to aspartate
Externí odkaz:
https://doaj.org/article/3c08b86bee9840319cb46a8d07a448b4
Autor:
Mohsen Khademi, Ann M Dring, Jonathan D Gilthorpe, Anna Wuolikainen, Faiez Al Nimer, Robert A Harris, Magnus Andersson, Lou Brundin, Fredrik Piehl, Tomas Olsson, Anders Svenningsson
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63172 (2013)
Inflammatory mediators have crucial roles in leukocyte recruitment and subsequent central nervous system (CNS) neuroinflammation. The extent of neuronal injury and axonal loss are associated with the degree of CNS inflammation and determine physical
Externí odkaz:
https://doaj.org/article/14b90a546e7f4ed99a4f715747416212
Autor:
Jeong-Kook Kim, Joon-Young Kim, Han-Jong Kim, Keun-Gyu Park, Robert A Harris, Won-Jea Cho, Jae-Tae Lee, In-Kyu Lee
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80391 (2013)
Scoparone, a natural compound isolated from Artemisia capillaris, has been used in Chinese herbal medicine to treat neonatal jaundice. Signal transducer and activator of transcription 3 (STAT3) contributes to the growth and survival of many human tum
Externí odkaz:
https://doaj.org/article/cea8fcb941f7468cb1388b74ce84c8d8
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71997 (2013)
Pyruvate dehydrogenase kinases (PDK1-4) play a critical role in the inhibition of the mitochondrial pyruvate dehydrogenase complex especially when blood glucose levels are low and pyruvate can be conserved for gluconeogenesis. Under diabetic conditio
Externí odkaz:
https://doaj.org/article/3b40615f220941d793df83f1fbc523f0
Autor:
Maha-Hamadien Abdulla, Moiz Bakhiet, Veerle Lejon, Jan Andersson, James McKerrow, Omar Al-Obeed, Robert A Harris
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79281 (2013)
Trypanosome-derived lymphocyte triggering factor (TLTF) is a molecule released by African trypanosomes that interacts with the host immune system, resulting in increased levels of IFN-γ production.TLTF and anti-TLTF antibodies were assessed in sera
Externí odkaz:
https://doaj.org/article/a19c757a53de434f8cd2da8c447f2742
Autor:
Ja Hee Lee, Eun-Jin Kim, Don-Kyu Kim, Ji-Min Lee, Seung Bum Park, In-Kyu Lee, Robert A Harris, Mi-Ock Lee, Hueng-Sik Choi
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46324 (2012)
Multiple cellular signaling pathways that control metabolism and survival are activated when cell are incubated under hypoxic conditions. Activation of the hypoxia inducible factor (HIF)-1 promotes expression of genes that increase the capacity to co
Externí odkaz:
https://doaj.org/article/a110d7abfb5c496dadb89d59f098fd05
Autor:
Alan Gillett, Klio Maratou, Chris Fewings, Robert A Harris, Maja Jagodic, Tim Aitman, Tomas Olsson
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7773 (2009)
BACKGROUND: Multiple Sclerosis (MS) is a chronic inflammatory disease causing demyelination and nerve loss in the central nervous system. Experimental autoimmune encephalomyelitis (EAE) is an animal model of MS that is widely used to investigate comp
Externí odkaz:
https://doaj.org/article/d5a58a1450794be7878c5c683be2cad4
Autor:
Asa Andersson, Magnus Isaksson, Judit Wefer, Anna Norling, Amilcar Flores-Morales, Fredrik Rorsman, Olle Kämpe, Robert A Harris, Anna Lobell
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3682 (2008)
BACKGROUND: We have previously shown that vaccination with DNA encoding the encephalitogenic peptide myelin oligodendrocyte glycoprotein (MOG)(91-108) (pMOG) suppresses MOG(91-108)-induced rat Experimental Autoimmune Encephalomyelitis (EAE), a model
Externí odkaz:
https://doaj.org/article/81ac7dd80c03478c82629d2ba472e392
Publikováno v:
Injury. 54:1711-1715