Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Robert A Charvat"'
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0226807 (2020)
The continued evolution of antibiotic resistance has increased the urgency for new antibiotic development, leading to exploration of non-traditional sources. In particular, snake venom has garnered attention for its potent antibacterial properties. N
Externí odkaz:
https://doaj.org/article/bd736c79f3794aa3a0efc8c3d9a7b362
Publikováno v:
Microorganisms, Vol 8, Iss 8, p 1159 (2020)
Prevalence studies revealed that one-third of the human population is chronically infected with Toxoplasma gondii. Presently, such infections are without medical treatment that effectively eradicates the parasite once it is in its latent form. Moreov
Externí odkaz:
https://doaj.org/article/0c946c05f7654a798384b3977413b8a0
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
mBio
mBio, Vol 11, Iss 1, p e02732-19 (2020)
mBio
mBio, Vol 11, Iss 1, p e02732-19 (2020)
Toxoplasma gondii is an opportunistic pathogen that can cause devastating tissue damage in the immunocompromised and congenitally infected. Current therapies are not effective against all life stages of the parasite, and many cause toxic effects. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2173aa531fae06ae3dd970351fbc41
https://journals.asm.org/doi/10.1128/mBio.02732-19
https://journals.asm.org/doi/10.1128/mBio.02732-19
Autor:
Robert A. Charvat, William J. Sullivan, Irene Heredero-Bermejo, Joseph M. Varberg, Gustavo Arrizabalaga, Kylie Jacobs, Tamila Garbuz
Publikováno v:
Molecular Microbiology. 111:46-64
Dynamin-related proteins (Drps) are involved in diverse processes such as organelle division and vesicle trafficking. The intracellular parasite Toxoplasma gondii possesses three distinct Drps. TgDrpC, whose function remains unresolved, is unusual in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38fee3d43ffa68b47d18025bac8634b8
https://doi.org/10.1111/mmi.14138
https://doi.org/10.1111/mmi.14138
Publikováno v:
Journal of Student Research.
The exceedingly prevalent antibiotic resistance and need for effective antibiotic exploration has led researchers to a diverse array of biologically occurring compounds. In particular, snake venoms have antimicrobial properties and may be beneficial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d50faf40c9d31e5e7455792c4b0cf893
https://doi.org/10.47611/jsr.vi.667
https://doi.org/10.47611/jsr.vi.667
Publikováno v:
Journal of Student Research.
The normal intestinal microflora plays pivotal roles in aiding with digestion, stimulating the immune system, and providing protection from enteric pathogens. Despite the importance of these organisms, they are often an innocent bystander, caught in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dd2d0c0c34fa5641dd8832c0bfe4944
https://doi.org/10.47611/jsr.vi.668
https://doi.org/10.47611/jsr.vi.668
Publikováno v:
Microorganisms
Microorganisms, Vol 8, Iss 1159, p 1159 (2020)
Microorganisms, Vol 8, Iss 1159, p 1159 (2020)
Prevalence studies revealed that one-third of the human population is chronically infected with Toxoplasma gondii. Presently, there is no medical treatment for such infections, as the parasite is typically eradicated by the host’s immune system onc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd2a117e472c217f95d1624d9d27a8a
https://doi.org/10.3390/microorganisms8081159
https://doi.org/10.3390/microorganisms8081159
Autor:
Raeshelle M. Strobel, Robert A. Charvat, Justin L. Rheubert, Megan A. Pasternak, Sarah M. Klass
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 150
With the threat of a post-antibiotic era looming, the search for new and effective antibiotics from novel sources is imperative. Not only has crude snake venom been shown to be effective, but specific components within the venoms, such as Phospholipa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6beae43cb911913fd3c490efc1224e50
https://pubmed.ncbi.nlm.nih.gov/29800609
https://pubmed.ncbi.nlm.nih.gov/29800609
Publikováno v:
Virology. 449:25-34
The UL4 gene is conserved within the genome of defective interfering particles of equine herpesvirus type 1 (EHV-1) that mediate persistent infection. Here, we show that the UL4 protein inhibits EHV-1 reporter gene expression by decreasing the level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b73859cab635669b8ec921219c8458f2
https://doi.org/10.1016/j.virol.2013.11.005
https://doi.org/10.1016/j.virol.2013.11.005
Publikováno v:
Scientific Reports
The ionophore monensin displays potent activities against several coccidian parasites of veterinary and medical importance including the opportunistic pathogen of humans, Toxoplasma gondii. While monensin is used widely in animals, toxicity impedes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6fbbe4a5009598b45e61cfc4895bf4