Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Robert A Carrillo"'
Publikováno v:
eLife, Vol 9 (2020)
How circuit wiring is specified is a key question in developmental neurobiology. Previously, using the Drosophila motor system as a model, we found the classic temporal transcription factor Hunchback acts in NB7-1 neuronal stem cells to control the n
Externí odkaz:
https://doaj.org/article/100258bf13d34a0daab02dc44de87871
Autor:
James Ashley, Violet Sorrentino, Meike Lobb-Rabe, Sonal Nagarkar-Jaiswal, Liming Tan, Shuwa Xu, Qi Xiao, Kai Zinn, Robert A Carrillo
Publikováno v:
eLife, Vol 8 (2019)
The Drosophila larval neuromuscular system provides an ideal context in which to study synaptic partner choice, because it contains a small number of pre- and postsynaptic cells connected in an invariant pattern. The discovery of interactions between
Externí odkaz:
https://doaj.org/article/6df7118dc7a14dcd9d8f2b74758845cb
Autor:
Shouqiang Cheng, James Ashley, Justyna D Kurleto, Meike Lobb-Rabe, Yeonhee Jenny Park, Robert A Carrillo, Engin Özkan
Publikováno v:
eLife, Vol 8 (2019)
In stereotyped neuronal networks, synaptic connectivity is dictated by cell surface proteins, which assign unique identities to neurons, and physically mediate axon guidance and synapse targeting. We recently identified two groups of immunoglobulin s
Externí odkaz:
https://doaj.org/article/c4db496fe56f409992e9a98d78f757e4
Autor:
Yupu Wang, Rio J. Salazar, Luciano T. Simonetta, Violet Sorrentino, Terrence J. Gatton, Bill Wu, Christopher G. Vecsey, Robert A. Carrillo
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Our nervous system contains billions of neurons that form precise connections with each other through interactions between cell surface proteins. In Drosophila, the Dpr and DIP immunoglobulin protein subfamilies form homophilic or heterophil
Externí odkaz:
https://doaj.org/article/36896c53a65f474a9b6de99fcdf3208f
Autor:
Yupu Wang, Ruiling Zhang, Sihao Huang, Parisa Tajalli Tehrani Valverde, Meike Lobb-Rabe, James Ashley, Lalanti Venkatasubramanian, Robert A. Carrillo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Neuronal cell death and subsequent brain dysfunction are hallmarks of aging and neurodegeneration, but how the nearby healthy neurons (bystanders) respond to the death of their neighbors is not fully understood. In the Drosophila larval neur
Externí odkaz:
https://doaj.org/article/baf7eaa24d994b8e80893c2dbfc576ee
Autor:
Meike Lobb-Rabe, Katherine DeLong, Rio J. Salazar, Ruiling Zhang, Yupu Wang, Robert A. Carrillo
Publikováno v:
Neural Development, Vol 17, Iss 1, Pp 1-15 (2022)
Abstract The paths axons travel to reach their targets and the subsequent synaptic connections they form are highly stereotyped. How cell surface proteins (CSPs) mediate these processes is not completely understood. The Drosophila neuromuscular junct
Externí odkaz:
https://doaj.org/article/5481697b5ee5458090a4faaff66f514d
Autor:
D. Michael Franklin, Charles Silvestro, Robert A. Carrillo, Yewon Yang, Dharani Annadurai, Sangavai Ganesan, Divya Sai Jyothi Vasantham, Soujanya Mettu, Mehal Patel, Manasi S. Patil, Nandini Devi Akurathi
Publikováno v:
Frontiers in Virtual Reality, Vol 4 (2023)
Patients diagnosed with cancer experience a high degree of stress as well as side effects from treatments that can greatly impact their quality of life. Many patients experience long-term side effects such as pain, fatigue, anxiety, depression, and c
Externí odkaz:
https://doaj.org/article/e0776ef582f34336a614e3714f447cca
TheDrosophilaDpr and DIP proteins belong to the immunoglobulin superfamily of cell surface proteins (CSPs). Their hetero- and homophilic interactions have been implicated in a variety of neuronal functions, including synaptic connectivity, cell survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca279a8588af872ba585878d5c397ff8
https://doi.org/10.1101/2023.03.02.530872
https://doi.org/10.1101/2023.03.02.530872
Autor:
Yupu Wang, Meike Lobb-Rabe, James Ashley, Purujit Chatterjee, Veera Anand, Hugo J. Bellen, Oguz Kanca, Robert A. Carrillo
Publikováno v:
Development
In complex nervous systems, neurons must identify their correct partners to form synaptic connections. The prevailing model to ensure correct recognition posits that cell-surface proteins (CSPs) in individual neurons act as identification tags. Thus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31cf09884cd477151aa263635190f680
https://europepmc.org/articles/PMC9188756/
https://europepmc.org/articles/PMC9188756/
Publikováno v:
The Journal of Neuroscience. 41:1401-1417
Throughout the nervous system, the convergence of two or more presynaptic inputs on a target cell is commonly observed. The question we ask here is to what extent converging inputs influence each other's structural and functional synaptic plasticity.