Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Robert A, Maue"'
Autor:
Maximillian A. Rogers, Catherine C. Y. Chang, Robert A. Maue, Elaina M. Melton, Andrew A. Peden, William S. Garver, Junghoon Lee, Peter Schroen, Mitchell Huang, Ta-Yuan Chang
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance Niemann-Pick type C disease (NPCD) is an incurable genetic neurological disorder. Cells with NPC mutations fail to export cholesterol from endosomal organelle to multiple other organelles. ACAT1 is an enzyme that converts cholesterol to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a817a781ec7473dfbd6a89ca2b7e952a
https://doi.org/10.1073/pnas.2201646119
https://doi.org/10.1073/pnas.2201646119
Autor:
Shigeki Sugii, Patrick C. Reid, Nobutaka Ohgami, Yukiko Shimada, Robert A. Maue, Haruaki Ninomiya, Yoshiko Ohno-Iwashita, Ta-Yuan Chang
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 5, Pp 1033-1041 (2003)
BCθ is a proteolytically nicked and biotinylated derivative of a cholesterol binding protein perfringolysin O (θ-toxin), and has been used to detect cholesterol-rich domains at the plasma membrane (PM). Here we show that by modifying the cell fixat
Externí odkaz:
https://doaj.org/article/126374b3ddf84e7dac98a60a4e3ae71d
Autor:
Mitchell M. Huang, Peter W. Schroen, Ta-Yuan Chang, Andrew A. Peden, Elaina M. Melton, William S. Garver, Robert A. Maue, Catherine C.Y. Chang, Maximillian A. Rogers
Niemann-Pick type C (NPC) is a neurological disorder with no cure. NPC proteins deliver cholesterol from endosomes to other compartments including trans-Golgi network (TGN) and endoplasmic reticulum (ER). Acyl-coenzyme A:cholesterol acyltransferase 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9618278c3b5c0edc6606dae18ff3d85d
https://doi.org/10.1101/2020.08.07.241471
https://doi.org/10.1101/2020.08.07.241471
Autor:
Robert A. Maue, Stephen J. Bloor, Stephen L. Sturley, Dinindu S. Senanayake, Kirill Lagutin, Katsumi Higaki, Henry N. Ginsberg, Remy T. Schneider, Natalie Hammond, Andrew B. Munkacsi, Antonio Hernandez-Ono, Nicole Dahlson, Fannie W. Chen, Daniel S. Ory, Joyce J. Repa, Yiannis A. Ioannou
Publikováno v:
Journal of Biological Chemistry. 292:4395-4410
Niemann-Pick type C (NP-C) disease is a fatal genetic lipidosis for which there is no Food and Drug Administration (FDA)-approved therapy. Vorinostat, an FDA-approved inhibitor of histone deacetylases, ameliorates lysosomal lipid accumulation in cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f9284e1ed04dfa5c1da8744c3e7f660
https://doi.org/10.1074/jbc.m116.770578
https://doi.org/10.1074/jbc.m116.770578
Autor:
Andrew B, Munkacsi, Natalie, Hammond, Remy T, Schneider, Dinindu S, Senanayake, Katsumi, Higaki, Kirill, Lagutin, Stephen J, Bloor, Daniel S, Ory, Robert A, Maue, Fannie W, Chen, Antonio, Hernandez-Ono, Nicole, Dahlson, Joyce J, Repa, Henry N, Ginsberg, Yiannis A, Ioannou, Stephen L, Sturley
Publikováno v:
The Journal of biological chemistry. 292(11)
Niemann-Pick type C (NP-C) disease is a fatal genetic lipidosis for which there is no Food and Drug Administration (FDA)-approved therapy. Vorinostat, an FDA-approved inhibitor of histone deacetylases, ameliorates lysosomal lipid accumulation in cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3b903d993964132afab989954c6cb21
https://pubmed.ncbi.nlm.nih.gov/28031458
https://pubmed.ncbi.nlm.nih.gov/28031458
Autor:
Robert A. Maue, Brent T. Harris, Ivan A. Borbon, Christine M. Wooley, Maximillian A. Rogers, David J. Graber, Catherine C.Y. Chang, Robert W. Burgess, Leslie P. Henderson, Robert P. Erickson, Theodore P. Trouard, Marie T. Vanier, Carlos A. A. Penatti, Kevin L. Seburn, Bing Wang, John Totenhagen, Benjamin S. Szwergold, Ta-Yuan Chang, Donna M. Porter
Publikováno v:
Human Molecular Genetics. 21:730-750
We have identified a point mutation in Npc1 that creates a novel mouse model (Npc1(nmf164)) of Niemann-Pick type C1 (NPC) disease: a single nucleotide change (A to G at cDNA bp 3163) that results in an aspartate to glycine change at position 1005 (D1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3183f2b0e75b63b8fff7fd0c1c1717d6
https://doi.org/10.1093/hmg/ddr505
https://doi.org/10.1093/hmg/ddr505
Publikováno v:
Journal of Neurochemistry. 101:737-748
Cerebellar Purkinje neurons in vivo exhibit high frequency and multi-spike action potentials with transient (INaT), resurgent (INaR) and persistent (INaP) Na+ currents arising from voltage-gated Na+ channels, which play important roles in shaping the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::697cc7b234f449d8ce6472328ab34b94
https://doi.org/10.1111/j.1471-4159.2007.04470.x
https://doi.org/10.1111/j.1471-4159.2007.04470.x
Autor:
Robert A. Maue, Bridget Mudge, Linda J. von Reyn, Mary Jo Slattery, Bridget Linehan Logan, Karen Secore
Publikováno v:
Journal of professional nursing : official journal of the American Association of Colleges of Nursing. 32(6)
It is important for nurses today and for those joining the workforce in the future to have familiarity and training with respect to interprofessional research, evidence-based practice, and quality improvement. In an effort to address this need, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498781484ba460cdc12f34ff7aec1147
https://pubmed.ncbi.nlm.nih.gov/27964811
https://pubmed.ncbi.nlm.nih.gov/27964811
Autor:
Robert B. Campenot, Robert A. Maue, Dennis E. Vance, Barbara Karten, Hideki Hayashi, Jean E. Vance
Publikováno v:
Analytical Biochemistry. 331:1-16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b2557f34464220fbdbf1f72a21d8de
https://doi.org/10.1016/j.ab.2004.04.002
https://doi.org/10.1016/j.ab.2004.04.002
Publikováno v:
Journal of Neurobiology. 60:227-235
Voltage-gated K+ channels play important roles in shaping the characteristics of action potentials and electrical activity. In a previous study, we isolated cDNAs encoding several distinct K+ channel isoforms, including a novel isoform (XKv1.10) expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcc58e235e2474f2c10d704d6396c762
https://doi.org/10.1002/neu.20024
https://doi.org/10.1002/neu.20024