Zobrazeno 1 - 10
of 1 755
pro vyhledávání: '"Robert A, Lewis"'
Autor:
Nancy E. Sealover, Jacob M. Hughes, Patricia L. Theard, Deepan Chatterjee, Amanda J. Linke, Bridget A. Finniff, Brianna R. Daley, Robert E. Lewis, Robert L. Kortum
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103361- (2024)
Summary: Acquired resistance to oncogene-targeted therapies is the major driver of mortality for patients with cancer. Here, we present a 6-to-16-week assay to model the development of acquired resistance in adherent and suspension cancer cell lines.
Externí odkaz:
https://doaj.org/article/f0666369e1db465b8a5f5a2b715e72c7
Autor:
Joe Antoun, Anthony I. Shepherd, Jo Corbett, Nicholas C. Sangala, Robert J. Lewis, Emma Lane, Zoe L. Saynor
Publikováno v:
Physiological Reports, Vol 12, Iss 17, Pp n/a-n/a (2024)
Abstract People with end‐stage kidney disease (ESKD) often exhibit impaired cardiac structure and function, which may contribute to poor exercise capacity. This study used multimodal exercise testing to investigate the central and peripheral mechan
Externí odkaz:
https://doaj.org/article/89a3197ad45c4db2b71ec569d6e35acd
Autor:
Chaitra Rao, Danielle E Frodyma, Siddesh Southekal, Robert A Svoboda, Adrian R Black, Chittibabu Guda, Tomohiro Mizutani, Hans Clevers, Keith R Johnson, Kurt W Fisher, Robert E Lewis
Publikováno v:
eLife, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/706ac20d6e23427cb059a67f4a7e21d7
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-6 (2023)
Externí odkaz:
https://doaj.org/article/c437d559652a4fb7ab456eff05e9d9e8
Autor:
David G Kiely, Iain Armstrong, Robin Condliffe, Andrew J Swift, Allan Lawrie, Rafael Sauter, Jim Wild, Athanasios Charalampopoulos, Alex Rothman, Abdul Hameed, Smitha Rajaram, Judith Hurdman, Catherine Billings, Charlie Elliot, AA Roger Thompson, Robert A Lewis, Lisa Watson, Neil Hamilton, Steven Wood, Charlotte Durrington, Fernando Exposto, Ruvimbo Muzwidzwa, Louise Raiteri, Amélie Beaudet, Audrey Muller, Nadia Pillai, Rehan Quadery
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Objectives This study was conducted to evaluate the ability of risk assessment to predict healthcare resource utilisation (HCRU), costs, treatments, health-related quality of life (HRQoL) and survival in patients diagnosed with chronic thromboembolic
Externí odkaz:
https://doaj.org/article/3993aaf4b13943c7be76f4d6a5b3da06
Autor:
Robin Condliffe, Charlotte Durrington, Abdul Hameed, Robert A. Lewis, Rajamiyer Venkateswaran, Deepa Gopalan, Peter Dorfmüller
Publikováno v:
European Respiratory Review, Vol 32, Iss 170 (2023)
Pulmonary hypertension (PH) is defined by the presence of a mean pulmonary arterial pressure >20 mmHg. Current guidelines describe five groups of PH with shared pathophysiological and clinical features. In this paper, the first of a series covering a
Externí odkaz:
https://doaj.org/article/f586a7368df846618fa1032ce20be894
Republication of 'The Evaluation and Treatment of Diabetic Foot Ulcers and Diabetic Foot Infections'
Autor:
Michael A. Del Core MD, Junho Ahn BS, Robert B. Lewis MD, Katherine M. Raspovic DPM, Trapper A. J. Lalli MD, Dane K. Wukich MD
Publikováno v:
Foot & Ankle Orthopaedics, Vol 8 (2023)
Diabetic foot ulcers and infections are common complications of diabetic foot disease. Additionally, these complications are a common cause of morbidity and impose a substantial burden to the patient and society. It is imperative to understand the ma
Externí odkaz:
https://doaj.org/article/2eb5c91b4dfe45b1b14adba10a529708
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 5, Pp 1175-1181 (2021)
Abstract Objective An at home‐test for differentiating between conductive and sensorineural hearing loss remains elusive. Our goal was to validate the novel cell‐phone vibration test (CPVT) against the Weber tuning fork test (WTFT) and to assess
Externí odkaz:
https://doaj.org/article/98900ba9b89c4315a8bf31da4e0c4312
Autor:
Gustavo A Gomez, Charles H Rundle, Weirong Xing, Chandrasekhar Kesavan, Sheila Pourteymoor, Robert E Lewis, David R Powell, Subburaman Mohan
Publikováno v:
eLife, Vol 11 (2022)
Pathological obesity and its complications are associated with an increased propensity for bone fractures. Humans with certain genetic polymorphisms at the kinase suppressor of ras2 (KSR2) locus develop severe early-onset obesity and type 2 diabetes.
Externí odkaz:
https://doaj.org/article/7c9a30dcd13e411aadadae3da7822fee
Autor:
Ermanno Florio, Marcello Serra, Robert G. Lewis, Enikö Kramár, Michael Freidberg, Marcello Wood, Micaela Morelli, Emiliana Borrelli
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105263- (2022)
Summary: Degeneration of dopaminergic neurons leads to Parkinson’s disease (PD), characterized by reduced levels of striatal dopamine (DA) and impaired voluntary movements. DA replacement is achieved by levodopa treatment which in long-term causes
Externí odkaz:
https://doaj.org/article/e6de8d72e2b24bc7b5d341bb345751d3