Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Robert A, Kurt"'
Publikováno v:
Informatics in Medicine Unlocked, Vol 30, Iss , Pp 100939- (2022)
Previously, a modeling tool was used to construct a model of the TLR4 signaling cascade, and here the utility of the modeling tool in two dimensions – adaptability (different types of TLR cascades and readout systems) and power (the ease with which
Externí odkaz:
https://doaj.org/article/94edf8b225214f1db2e7ea4a20a9dba4
Autor:
Mary J. Higgins, Antonio Serrano, Kofi Y. Boateng, Victoria A. Parsons, Tiffany Phuong, Alyssa Seifert, Jacob M. Ricca, Kyle C. Tucker, Alec S. Eidelman, Maureen A. Carey, Robert A. Kurt
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 2016, Iss 10, Pp 157-167 (2016)
Externí odkaz:
https://doaj.org/article/86d7ff096eaa47ee8d234cd73dede443
Autor:
C. Zhang, Robert A. Kurt
Publikováno v:
Clinical and Translational Oncology. 22:2153-2161
With advances in checkpoint inhibitor and CAR T-cell therapies, among other advances in immunotherapy, this is an exciting time to be a tumor immunologist. We are witnessing the transition of decades of work at the bench leading to substantial succes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07dc42b2cba1e23030f6ed95f4fdfdbd
https://doi.org/10.1007/s12094-020-02368-w
https://doi.org/10.1007/s12094-020-02368-w
Publikováno v:
The Journal of Immunology. 208:61.11-61.11
Previously, we reported that macrophages at early tumor sites, before the tumors are even palpable, have a mixed phenotype with production of both pro- and anti-inflammatory cytokines, decreased production of reactive oxygen species, and increased de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6449f743dbaca2f5e65fd2234dd00449
https://doi.org/10.4049/jimmunol.208.supp.61.11
https://doi.org/10.4049/jimmunol.208.supp.61.11
Autor:
Chun Wai Liew, Robert A. Kurt
Publikováno v:
CourseSource. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::096dea01ab4b328db5042e02bed6432c
https://doi.org/10.24918/cs.2020.36
https://doi.org/10.24918/cs.2020.36
Autor:
Silvia Chilel Martin, Catherine M Newsom-Stewart, Robert A. Kurt, Matthew DeBenedetto, Amanda Lauricella, Alison Baranovic, Matthew Adusei, Jennifer Schwartz, Chenyu Zhang
Publikováno v:
Cellular immunology. 346
Here we used three different murine mammary carcinomas to study the immune environment associated with early tumor sites. While it was not surprising that the early immune response was predominated by macrophages and neutrophils, there were some nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298ada7f3f967aece9fbe468c29bff9a
https://pubmed.ncbi.nlm.nih.gov/31495445
https://pubmed.ncbi.nlm.nih.gov/31495445
Autor:
Carli B. Jones, DaMarcus A Ingram, Chun Wai Liew, Samantha E Evans, Tiffany Phuong, Stacy Nganga, Kendall Weedling, Justin Hoot, Robert A. Kurt
Publikováno v:
Computers in biology and medicine. 93
We developed an agent-based model to simulate a signaling cascade which allowed us to focus on the behavior of each class of agents independently of the other classes except when they were in physical contact. A critical piece was the ratio of the po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03e7f800c5b09e0804880a2d54bf984
https://pubmed.ncbi.nlm.nih.gov/29277001
https://pubmed.ncbi.nlm.nih.gov/29277001
Autor:
Robert A Kurt, Chenyu Zhang, Jennifer Schwartz, Amanda Lauricella, Matthew Adusei, Matthew DeBenedetto, Catherine Newsom-Stewart
Publikováno v:
The Journal of Immunology. 202:135.9-135.9
Most of what we know about tumor associated macrophages (TAM) and tumor associated neutrophils (TAN) comes from analysis of these cells isolated from solid tumors, or the periphery of humans or mice with solid tumors. These studies have largely led t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a3258f4b21c8ae0b869d612f94070f9
https://doi.org/10.4049/jimmunol.202.supp.135.9
https://doi.org/10.4049/jimmunol.202.supp.135.9
Autor:
Maureen A. Carey, Tiffany Phuong, Antonio Serrano, Alyssa Seifert, Kyle C. Tucker, Victoria A. Parsons, Mary Higgins, Alec Eidelman, Robert A. Kurt, Kofi Y. Boateng, Jacob M. Ricca
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 10 (2016)
Breast Cancer: Basic and Clinical Research, Vol 2016, Iss 10, Pp 157-167 (2016)
Breast Cancer : Basic and Clinical Research
Breast Cancer: Basic and Clinical Research, Vol 2016, Iss 10, Pp 157-167 (2016)
Breast Cancer : Basic and Clinical Research
Previous data obtained in our laboratory suggested that there may be constitutive signaling through the myeloid differentiation primary response gene 88 (Myd88)-dependent signaling cascade in murine mammary carcinoma. Here, we extended these findings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1463720fc111a7ef6c9a5fc1117ad3
https://doaj.org/article/c2d6a2a71e7e4291aa8e64affdc0311e
https://doaj.org/article/c2d6a2a71e7e4291aa8e64affdc0311e
Publikováno v:
Cell Research. 23:394-408
CCL5 is a member of the CC chemokine family expressed in a wide array of immune and non-immune cells in response to stress signals. CCL5 expression correlates with advanced human breast cancer. However, its functional significance and mode of action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c810b1f2aba4d9c8c35504c60267a98
https://doi.org/10.1038/cr.2012.178
https://doi.org/10.1038/cr.2012.178