Zobrazeno 1 - 10
of 3 123
pro vyhledávání: '"Robert A, Hoffman"'
Autor:
Chunlin Lin, Penghang Lin, Huayan Lin, Hengxin Yao, Songyi Liu, Ruofan He, Hui Chen, Zuhong Teng, Robert M. Hoffman, Jianxin Ye, Guangwei Zhu
Publikováno v:
Oncogenesis, Vol 12, Iss 1, Pp 1-16 (2023)
Abstract Colorectal cancer (CRC) is a formidable disease due to the intricate mechanisms that drive its proliferation and metastasis. Despite significant progress in cancer research, the integration of these mechanisms that influence cancer cell beha
Externí odkaz:
https://doaj.org/article/60672eb4ed3f487e8c81589a0ef27c76
Autor:
Ayami Hasegawa-Haruki, Koya Obara, Nanako Takaoka, Kyoumi Shirai, Yuko Hamada, Nobuko Arakawa, Ryoichi Aki, Robert M Hoffman, Yasuyuki Amoh
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304676 (2024)
Diabetes often results in chronic ulcers that fail to heal. Effective treatment for diabetic wounds has not been achieved, although stem-cell-treatment has shown promise. Hair-follicle-associated-pluripotent (HAP)-stem-cells from bulge area of mouse
Externí odkaz:
https://doaj.org/article/d3110f468ea04a87b6e216638bcddb58
Autor:
Nanako Takaoka, Michiko Yamane, Ayami Hasegawa, Koya Obara, Kyoumi Shirai, Ryoichi Aki, Hiroyasu Hatakeyama, Yuko Hamada, Nobuko Arakawa, Manabu Tanaka, Robert M Hoffman, Yasuyuki Amoh
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0297443 (2024)
There has been only limited success to differentiate adult stem cells into cardiomyocyte subtypes. In the present study, we have successfully induced beating atrial and ventricular cardiomyocytes from rat hair-follicle-associated pluripotent (HAP) st
Externí odkaz:
https://doaj.org/article/dacbf2db30c648da89349c16824f1989
Autor:
Michael A. Turner, Kristin E. Cox, Shanglei Liu, Nicholas Neel, Siamak Amirfakhri, Hiroto Nishino, Mojgan Hosseini, Joshua A. Alcantara, Amer Ali Abd El-Hafeez, Thinzar M. Lwin, Kavita Mallya, Joseph R. Pisegna, Satish K. Singh, Pradipta Ghosh, Robert M. Hoffman, Surinder K. Batra, Michael Bouvet
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 4, Pp 3347-3358 (2023)
Poor visualization of polyps can limit colorectal cancer screening. Fluorescent antibodies to mucin5AC (MUC5AC), a glycoprotein upregulated in adenomas and colorectal cancer, could improve screening colonoscopy polyp detection rate. Adenomatous polyp
Externí odkaz:
https://doaj.org/article/0a7999883a40427280a4ee5a75ae457b
Autor:
Senada Hajdarevic, Cecilia Högberg, Mercè Marzo-Castillejo, Vija Siliņa, Jolanta Sawicka-Powierza, Magadalena Esteva, Tuomas Koskela, Davorina Petek, Sara Contreras-Martos, Marcello Mangione, Zlata Ožvačić Adžić, Radost Asenova, Svjetlana Gašparović Babić, Mette Brekke, Krzysztof Buczkowski, Nicola Buono, Saliha Serap Çifçili, Geert-Jan Dinant, Babette Doorn, Robert D Hoffman, George Kuodza, Peter Murchie, Liina Pilv, Aida Puia, Aurimas Rapalavicius, Emmanouil Smyrnakis, Birgitta Weltermann, Michael Harris
Publikováno v:
BJGP Open, Vol 7, Iss 4 (2023)
Background: While primary care physicians (PCPs) play a key role in cancer detection, they can find cancer diagnosis challenging, and some patients have considerable delays between presentation and onward referral. Aim: To explore European PCPs’ ex
Externí odkaz:
https://doaj.org/article/d44cbdbac2844f98a5643ab2463bd71e
Autor:
Yanyu Jiang, Zhimei Tang, Xiaogang Zhu, Biying Xiao, Hechuan Tian, Xingxing Lei, Huan Peng, Jun Qin, Yanmei Zhang, Robert M. Hoffman, Xiaorong Hu, Qiu Chen, Guang Ji, Lijun Jia
Publikováno v:
MedComm, Vol 4, Iss 6, Pp n/a-n/a (2023)
Abstract Fasting has been grown in popularity with multiple potential benefits. However, very few studies dynamically monitor physiological and pathological changes during long‐term fasting using noninvasive methods. In the present study, we recrui
Externí odkaz:
https://doaj.org/article/cebe02e949d24cd8a1ee34245b4c5cca
Autor:
Marc Ghannoum, Sophie Gosselin, Robert S. Hoffman, Valery Lavergne, Bruno Mégarbane, Hossein Hassanian-Moghaddam, Maria Rif, Siba Kallab, Steven Bird, David M. Wood, Darren M. Roberts, for the EXTRIP Workgroup
Publikováno v:
Critical Care, Vol 27, Iss 1, Pp 1-33 (2023)
Abstract Ethylene glycol (EG) is metabolized into glycolate and oxalate and may cause metabolic acidemia, neurotoxicity, acute kidney injury (AKI), and death. Historically, treatment of EG toxicity included supportive care, correction of acid–base
Externí odkaz:
https://doaj.org/article/69147d2763e14bdf93d6f22f5675c958
Autor:
Penghang Lin, Chunlin Lin, Ruofan He, Hui Chen, Zuhong Teng, Hengxin Yao, Songyi Liu, Robert M. Hoffman, Jianxin Ye, Guangwei Zhu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Colorectal cancer cannot be completely cured at present, and it is still an important clinical medical problem. TRAF6 is highly expressed in many malignant tumors. However, the role of TRAF6 in colorectal cancer is still controversial, mainl
Externí odkaz:
https://doaj.org/article/25234541ad1c49eebfe133f7b33b12e3
Autor:
Koya Obara, Jose Reynoso, Yuko Hamada, Yusuke Aoki, Yutaro Kubota, Noriyuki Masaki, Yasuyuki Amoh, Robert M. Hoffman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Stimulation of hair growth in hair loss has been a difficult goal to achieve. Hair follicle-associated pluripotent (HAP) stem cells express nestin and have been shown to differentiate to multiple cell types including keratinocytes, neurons,
Externí odkaz:
https://doaj.org/article/99609dc74f7f42f284f939019321b60a
Publikováno v:
Frontiers in Computer Science, Vol 5 (2023)
IntroductionThe purpose of the Stakeholder Playbook is to enable the developers of explainable AI systems to take into account the different ways in which different stakeholders or role-holders need to “look inside” the AI/XAI systems.MethodWe co
Externí odkaz:
https://doaj.org/article/f699f78914d745adb251e3955c25c686