Zobrazeno 1 - 10
of 3 175
pro vyhledávání: '"Robert A, Harris"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Thioflavin-T (THT) is a common and indispensable tool for the study of amyloid pathologies and protein aggregation, both in vitro and for histological samples. In this study we expand the use of THT beyond its canonical usage for staining am
Externí odkaz:
https://doaj.org/article/1f7bb5944dd44f0db46f868c0222d40c
Autor:
Marshall Williams, Robert M. Harris
Publikováno v:
Orthopaedic Surgery, Vol 16, Iss 6, Pp 1277-1283 (2024)
Objective Primary joint arthroplasty (JA) is one of the most common operating room (OR) procedures, with knee and hip arthroplasties being listed in the top five most frequent OR procedures and while not as common, shoulder arthroplasties are increas
Externí odkaz:
https://doaj.org/article/f0887e7f4cbf446f9e25d48f7bf93bad
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Microbes have been suspected to cause Alzheimer’s disease since at least 1908, but this has generally remained unpopular in comparison to the amyloid hypothesis and the dominance of Aβ and Tau. However, evidence has been accumulating to suggest th
Externí odkaz:
https://doaj.org/article/164b317cab8c4290a00fa01e8ff883c8
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The pathophysiology of ALS involves many signs of a disruption in copper homeostasis, with both excess free levels and functional deficiency likely occurring simultaneously. This is crucial, as many important physiological functions are performed by
Externí odkaz:
https://doaj.org/article/62850bcf9c174f978d99f277e6a30573
Autor:
Subramanyam R. Chinreddy, Nicole Tendayi Mashozhera, Badraldeen Rashrash, Gerardo Flores-Iga, Padma Nimmakayala, Gerald R. Hankins, Robert T. Harris, Umesh K. Reddy
Publikováno v:
Molecules, Vol 29, Iss 19, p 4729 (2024)
Cancer is a global health challenge with rising incidence and mortality rates, posing significant concerns. The World Health Organization reports cancer as a leading cause of death worldwide, contributing to nearly one in six deaths. Cancer pathogene
Externí odkaz:
https://doaj.org/article/ff0796e2d9af4aeda9c4b9fd9cb4959e
Autor:
Andrew R. Gorman, Gareth J. Crutchley, Dylan R. Baker, Douglas R. A. Fraser, Stuart A. Henrys, Anne M. Tréhu, Robert N. Harris, Benjamin J. Phrampus, Ingo A. Pecher
Publikováno v:
Geochemistry, Geophysics, Geosystems, Vol 25, Iss 3, Pp n/a-n/a (2024)
Abstract The Hikurangi Margin east of New Zealand's North Island hosts an extensive gas hydrate province with numerous gas hydrate accumulations related to the faulted structure of the accretionary wedge. One such hydrate feature occurs in a small pe
Externí odkaz:
https://doaj.org/article/76fa92c4b74340ff928da023a2e0fc08
Publikováno v:
European Journal of Obstetrics & Gynecology and Reproductive Biology: X, Vol 21, Iss , Pp 100272- (2024)
Intramural pregnancies (IMP) are very rare and represent about 1% of ectopic pregnancies (EPs). Despite a few reported cases, there is limited awareness & knowledge among sonographers and physicians. Moreover, no established diagnostic or treatment p
Externí odkaz:
https://doaj.org/article/59e3d106310e48b4b53d5dc2cec64fdb
Autor:
Seungwon An, Balachandar Nedumaran, Hong Koh, Dong Jin Joo, Hyungjo Lee, Chul-Seung Park, Robert A. Harris, Keong Sub Shin, Ali R. Djalilian, Yong Deuk Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 7, Pp 1556-1569 (2023)
Abstract Melatonin is involved in the regulation of various biological functions. Here, we explored a novel molecular mechanism by which the melatonin-induced sestrin2 (SESN2)-small heterodimer partner (SHP) signaling pathway protects against fasting
Externí odkaz:
https://doaj.org/article/ec0700fedd614f35a163c6cf6050fdd6
Autor:
Silvia Crescioli, Isabel Correa, Joseph Ng, Zena N. Willsmore, Roman Laddach, Alicia Chenoweth, Jitesh Chauhan, Ashley Di Meo, Alexander Stewart, Eleni Kalliolia, Elena Alberts, Rebecca Adams, Robert J. Harris, Silvia Mele, Giulia Pellizzari, Anna B. M. Black, Heather J. Bax, Anthony Cheung, Mano Nakamura, Ricarda M. Hoffmann, Manuela Terranova-Barberio, Niwa Ali, Ihor Batruch, Antoninus Soosaipillai, Ioannis Prassas, Antigona Ulndreaj, Miyo K. Chatanaka, Rosamund Nuamah, Shichina Kannambath, Pawan Dhami, Jenny L. C. Geh, Alastair D. MacKenzie Ross, Ciaran Healy, Anita Grigoriadis, David Kipling, Panagiotis Karagiannis, Deborah K. Dunn-Walters, Eleftherios P. Diamandis, Sophia Tsoka, James Spicer, Katie E. Lacy, Franca Fraternali, Sophia N. Karagiannis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract B cells are known to contribute to the anti-tumor immune response, especially in immunogenic tumors such as melanoma, yet humoral immunity has not been characterized in these cancers to detail. Here we show comprehensive phenotyping in sampl
Externí odkaz:
https://doaj.org/article/ec79417fc51f4749a49432bb35eb4eff
Autor:
Themis Thoudam, Dipanjan Chanda, Jung Yi Lee, Min-Kyo Jung, Ibotombi Singh Sinam, Byung-Gyu Kim, Bo-Yoon Park, Woong Hee Kwon, Hyo-Jeong Kim, Myeongjin Kim, Chae Won Lim, Hoyul Lee, Yang Hoon Huh, Caroline A. Miller, Romil Saxena, Nicholas J. Skill, Nazmul Huda, Praveen Kusumanchi, Jing Ma, Zhihong Yang, Min-Ji Kim, Ji Young Mun, Robert A. Harris, Jae-Han Jeon, Suthat Liangpunsakul, In-Kyu Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Ca2+ overload-induced mitochondrial dysfunction is considered a contributing factor alcohol-associated liver disease pathogenesis. Here the authors report that PDK4 promotes Ca2 + -channelling complex formation at the endoplasmic reticulum-mitochondr
Externí odkaz:
https://doaj.org/article/ca818281f2e2456cb8d5bb15f28a64a9