Zobrazeno 1 - 10
of 2 326
pro vyhledávání: '"Robert A, Baker"'
Autor:
Jia Zhao, Shenghui Liang, Haoning Howard Cen, Yanjun Li, Robert K. Baker, Balwinder Ruprai, Guang Gao, Chloe Zhang, Huixia Ren, Chao Tang, Liangyi Chen, Yanmei Liu, Francis C. Lynn, James D. Johnson, Timothy J. Kieffer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Remarkable advances in protocol development have been achieved to manufacture insulin-secreting islets from human pluripotent stem cells (hPSCs). Distinct from current approaches, we devised a tunable strategy to generate islet spheroids enr
Externí odkaz:
https://doaj.org/article/1bdf64aed5f74d41bf7cbec2f67ff56c
Publikováno v:
Physiologia, Vol 4, Iss 2, Pp 202-212 (2024)
Exercise physiology is the science that studies the processes of physical activity and their impact on the body. It usually requires a multidisciplinary approach with a team of experts because of the multiple physiological systems involved. At the ce
Externí odkaz:
https://doaj.org/article/881f51b60216496eb36005a7748a51ed
Publikováno v:
Applications in Plant Sciences, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Premise Most traits are polygenic and most genes are pleiotropic, resulting in complex, integrated phenotypes. Polyploidy presents an excellent opportunity to explore the evolution of phenotypic integration as entire genomes are duplicated,
Externí odkaz:
https://doaj.org/article/cdcd9d929ed9435d8e19d11ffb6f0176
Autor:
Diepiriye G. Iworima, Robert K. Baker, Cara Ellis, Chris Sherwood, Lisa Zhan, Alireza Rezania, James M. Piret, Timothy J. Kieffer
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-27 (2024)
Abstract Background Diabetes is a disease affecting over 500 million people globally due to insulin insufficiency or insensitivity. For individuals with type 1 diabetes, pancreatic islet transplantation can help regulate their blood glucose levels. H
Externí odkaz:
https://doaj.org/article/eef5378a3b1e42df99f87e9d84023768
Autor:
Mitchell J. S. Braam, Jia Zhao, Shenghui Liang, Shogo Ida, Nick K. Kloostra, Diepiriye G. Iworima, Mei Tang, Robert K. Baker, Nina Quiskamp, James M. Piret, Timothy J. Kieffer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract The generation of functional β-cells from human pluripotent stem cells (hPSCs) for cell replacement therapy and disease modeling of diabetes is being investigated by many groups. We have developed a protocol to harvest and aggregate hPSC-de
Externí odkaz:
https://doaj.org/article/fad7c7701c714b55ac516ffdf75998a9
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Introduction: Human pluripotent stem cells (hPSCs) provide many opportunities for application in regenerative medicine due to their ability to differentiate into cells from all three germ layers, proliferate indefinitely, and replace damaged or dysfu
Externí odkaz:
https://doaj.org/article/ea6232bfd13f4492920ebb3a18c3c90b
Autor:
Nikhil Mistry, Gregory M.T. Hare, Nadine Shehata, Robert S. Kramer, Hosam F. Fawzy, Robert A. Baker, Paula Carmona, Richard Saczkowski, Daniela Filipescu, Christella S. Alphonsus, Antoine Rochon, Alexander J. Gregory, Boris Khanykin, Jonathan D. Leff, Eva Mateo, Dimos Karangelis, Juan C. Tellez, Tarit Saha, Dennis T. Ko, Duminda N. Wijeysundera, Subodh Verma, C. David Mazer
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107429- (2023)
Summary: Biological evidence supports plasma methemoglobin as a biomarker for anemia-induced tissue hypoxia. In this translational planned substudy of the multinational randomized controlled transfusion thresholds in cardiac surgery (TRICS-III) trial
Externí odkaz:
https://doaj.org/article/0710fcafc7104deca2f47d6b847a2938
Autor:
Behzad Imanian, John Donaghy, Tim Jackson, Sanjay Gummalla, Balasubramanian Ganesan, Robert C. Baker, Matthew Henderson, Emily K. Butler, Yingying Hong, Brendan Ring, Clare Thorp, Ramin Khaksar, Mansour Samadpour, Kahlil A. Lawless, Iain MacLaren-Lee, Heather A. Carleton, Renmao Tian, Wei Zhang, Jason Wan
Publikováno v:
npj Science of Food, Vol 6, Iss 1, Pp 1-6 (2022)
Abstract The development and application of modern sequencing technologies have led to many new improvements in food safety and public health. With unprecedented resolution and big data, high-throughput sequencing (HTS) has enabled food safety specia
Externí odkaz:
https://doaj.org/article/b0dfcbe34a3b45dfb08324184157a6b7
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background Undergoing cardiac surgery often result in perioperative loss of health-related quality of life (HRQOL). Although participation rates in Australia is low, cardiac rehabilitation (CR) has been demonstrated to improve patient HRQOL
Externí odkaz:
https://doaj.org/article/8fe5a3c52286454d921bbe8f619d8706
Autor:
Clare Heal, Nadarajah Kangaharan, Marcus Ilton, Andrew Webster, Rosemary Wyber, Bo Remenyi, Zhiqiang Wang, Robert A Baker, Alan Cass, Ross Roberts-Thomson, Nigel Gray, Malcolm McDonald, James Doran, David Canty, Karen Dempsey, Georgie Brunsdon, Colin Royse, Alistair Royse, Jacqueline Mein, Jayme Bennetts, Maida Stewart, Steven Sutcliffe, Benjamin Reeves, Upasna Doran, Patricia Rankine, Richard Fejo, Elisabeth Heenan, Ripudaman Jalota, Jason King, Jonathan Doran, Joshua Hanson
Publikováno v:
BMJ Global Health, Vol 8, Iss 3 (2023)
Background Between 1964 and 1996, the 10-year survival of patients having valve replacement surgery for rheumatic heart disease (RHD) in the Northern Territory, Australia, was 68%. As medical care has evolved since then, this study aimed to determine
Externí odkaz:
https://doaj.org/article/f922c575b35e4c2abbe761839ac3157b