Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Robert Westwood"'
Autor:
Thomas R. Jackson, Aini Vuorinen, Laia Josa-Culleré, Katrina S. Madden, Daniel Conole, Thomas J. Cogswell, Isabel V.L. Wilkinson, Laura M. Kettyle, Douzi Zhang, Alison O’Mahony, Deanne Gracias, Lorna McCall, Robert Westwood, Georg C. Terstappen, Stephen G. Davies, Edward W. Tate, Graham M. Wynne, Paresh Vyas, Angela J. Russell, Thomas A. Milne
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104787- (2022)
Summary: Despite much progress in developing better drugs, many patients with acute myeloid leukemia (AML) still die within a year of diagnosis. This is partly because it is difficult to identify therapeutic targets that are effective across multiple
Externí odkaz:
https://doaj.org/article/41383f2f5a8d4ffeb2940ad8bb573d15
Hong Kong Management and Labour argues, in a series of previously unpublished, completely up-to-date contributions, that economic and social change has been ongoing in Hong Kong for many years, and political change is perhaps less important for labou
Autor:
A Vuorinen, Stephen G. Davies, Thomas R. Jackson, Edward W. Tate, O’Mahony A, Gracias D, Daniel Conole, Douzi Zhang, Katrina S. Madden, Thomas J. Cogswell, Wilkinson Ivl., Robert Westwood, Graham Michael Wynne, Laia Josa-Culleré, Andrew Russell, Kettyle Lm, McCall L, Terstappen Gc, Paresh Vyas, Thomas A. Milne
Acute Myeloid Leukaemia (AML) continues to have a poor prognosis, especially in the elderly. One reason for this is that many treatment regimens are not well tolerated by elderly patients. Much current focus is on the development of therapies that ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29d1fed02635c076e4bc29741abfc5df
https://doi.org/10.1101/2021.06.03.446952
https://doi.org/10.1101/2021.06.03.446952
Autor:
Carole J. R. Bataille, Matthew J. Durbin, Angela J. Russell, Anna Nadali, Méabh B. Brennan, Robert Westwood, Stefan Knapp, Oleg Fedorov, Roderick G. Walker, Kilian Huber, Graham Michael Wynne, Stephen G. Davies, Alan M. Jones, Gu Liu, Camilo E. Quevedo, Simon Byrne
The PIM family of serine/threonine kinases have become an attractive target for anti-cancer drug development, particularly for certain hematological malignancies. Here, we describe the discovery of a series of inhibitors of the PIM kinase family usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dbafee2ae06cfe33f43c280c5e18964
https://ora.ox.ac.uk/objects/uuid:7b0cdcdc-22cb-46f9-9a3a-f3e33a8b468d
https://ora.ox.ac.uk/objects/uuid:7b0cdcdc-22cb-46f9-9a3a-f3e33a8b468d
Autor:
Robert Westwood, Stephen G. Davies, Graham Michael Wynne, Andrew Russell, Peter D. Kennewell, Laurence Silpa
We have recently introduced the term “stemistry” to describe the search for low molecular weight compounds, which are able to selectively modulate the behavior of resident stem and stemlike or progenitor cells within the tissues in which they exi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::591bbdc24a1fa05f08768125712e58ad
https://doi.org/10.1016/b978-0-12-409547-2.12296-6
https://doi.org/10.1016/b978-0-12-409547-2.12296-6
Autor:
Allanah Johnston, Robert Westwood
Publikováno v:
Organization. 19:787-808
This article analyses a study that reveals employees using humour to resist an organization’s normative control attempts via a ‘workplace justice’ program. In an interesting ‘doubling’, the program used excerpts from the television comedy T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bad8ab947e9c3cd562819e6dccad32a
https://doi.org/10.1177/1350508411422583
https://doi.org/10.1177/1350508411422583
Publikováno v:
Human Relations. 63:1417-1438
A field study focused on a Western-led Corporate Social Responsibility (CSR) intervention into Pakistan’s soccer ball industry is used to explore the dynamics surrounding local Non-Governmental Organization (NGO) staff charged with implementation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd402c481bbde5c98d9db65991cd1482
https://doi.org/10.1177/0018726709359330
https://doi.org/10.1177/0018726709359330
Autor:
Robert Westwood, Graham Michael Wynne, Stephen G. Davies, Angela J. Russell, Peter T. Seden, Peter D. Kennewell
Publikováno v:
Journal of medicinal chemistry. 58(7)
A new paradigm for drug research has emerged, namely the deliberate search for molecules able to selectively affect the proliferation, differentiation, and migration of adult stem cells within the tissues in which they exist. Recently, there has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dafd5881c64301a65375f472b68a527
https://pubmed.ncbi.nlm.nih.gov/25590360
https://pubmed.ncbi.nlm.nih.gov/25590360
Publikováno v:
Tetrahedron Letters. 47:5139-5142
New pyrrolo derivatives of benzo[b]thiophene 1, 1-dioxide have been synthesised via 1, 3-dipolar cycloaddition reactions. Reaction of benzo[b]thiophene 1, 1-dioxide with stabilised azomethine ylides gave products in low yield but high stereoselectivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15adf23e08c4cb1b011a3188f235e1f3
https://doi.org/10.1016/j.tetlet.2006.05.064
https://doi.org/10.1016/j.tetlet.2006.05.064
Autor:
Robert Westwood, Carl Rhodes
Accessible and amusing in style, Humour, Work and Organization explores the critical, subversive and ambivalent character of humour, work and comedy as it relates to organizations and organized work. It examines the various individual, organizational