Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Robert Månsson"'
Autor:
Tsu-Yi Su, Julia Hauenstein, Ece Somuncular, Özge Dumral, Elory Leonard, Charlotte Gustafsson, Efthymios Tzortzis, Aurora Forlani, Anne-Sofie Johansson, Hong Qian, Robert Månsson, Sidinh Luc
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Age is a risk factor for hematologic malignancies. Attributes of the aging hematopoietic system include increased myelopoiesis, impaired adaptive immunity, and a functional decline of the hematopoietic stem cells (HSCs) that maintain hematop
Externí odkaz:
https://doaj.org/article/ce8fe9bb60494b84ad3652fa933d6098
Autor:
Charlotte Gustafsson, Julia Hauenstein, Nicolai Frengen, Aleksandra Krstic, Sidinh Luc, Robert Månsson
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background RNA sequencing has become the mainstay for studies of gene expression. Still, analysis of rare cells with random hexamer priming – to allow analysis of a broader range of transcripts – remains challenging. Results We here desc
Externí odkaz:
https://doaj.org/article/475c5e7efaf047b1b251070b2fd94b80
Autor:
Julia Minderjahn, Alexander Fischer, Konstantin Maier, Karina Mendes, Margit Nuetzel, Johanna Raithel, Hanna Stanewsky, Ute Ackermann, Robert Månsson, Claudia Gebhard, Michael Rehli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
How chromatin structure and gene accessibility changes during monocyte differentiation is not clearly defined. Here the authors characterize the chromatin changes during macrophage or dendritic cell maturation from monocytes and the dependence of thi
Externí odkaz:
https://doaj.org/article/9b3ed1fbfa844e7484ae6ceb15b31a69
Autor:
Tom A. Mulder, Maria L. Andersson, Lucía Peña-Pérez, Kia Heimersson, Ioanna Xagoraris, Björn E. Wahlin, Robert Månsson, Lotta Hansson, Georgios Rassidakis, Marzia Palma
Publikováno v:
HemaSphere, Vol 6, Iss 11, p e794 (2022)
In classical Hodgkin lymphoma (cHL), the malignant cells represent only a small fraction of the tumor. Yet, they orchestrate a lymphocyte-dominated tumor microenvironment (TME) that supports their survival and growth. The systemic effects of this loc
Externí odkaz:
https://doaj.org/article/cc4447832abb4e908ef84d3a2850cd88
Autor:
Tom A. Mulder, Maria L. Andersson, Lucia Peña-Pérez, Kia Heimersson, Ioanna Xagoraris, Björn E. Wahlin, Robert Månsson, Lotta Hansson, Georgios Z. Rassidakis, Marzia Palma
Publikováno v:
HemaSphere, Vol 6, Pp 15-16 (2022)
Externí odkaz:
https://doaj.org/article/df75b3c76f7d4ab7b4da4c1155415b62
Autor:
Thuy T. Luu, Jonas Nørskov Søndergaard, Lucía Peña-Pérez, Shabnam Kharazi, Aleksandra Krstic, Stephan Meinke, Laurent Schmied, Nicolai Frengen, Yaser Heshmati, Marcin Kierczak, Thibault Bouderlique, Arnika Kathleen Wagner, Charlotte Gustafsson, Benedict J. Chambers, Adnane Achour, Claudia Kutter, Petter Höglund, Robert Månsson, Nadir Kadri
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Natural killer (NK) cells play roles in viral clearance and early surveillance against malignant transformation, yet our knowledge of the underlying mechanisms controlling their development and functions remain incomplete. To reveal cell fate-determi
Externí odkaz:
https://doaj.org/article/c1dc67fc499e4b4183fc91fffcbae0a1
Autor:
Lucía Peña-Pérez, Shabnam Kharazi, Nicolai Frengen, Aleksandra Krstic, Thibault Bouderlique, Julia Hauenstein, Minghui He, Ece Somuncular, Xiaoze Li Wang, Carin Dahlberg, Charlotte Gustafsson, Ann-Sofie Johansson, Julian Walfridsson, Nadir Kadri, Petter Woll, Marcin Kierczak, Hong Qian, Lisa Westerberg, Sidinh Luc, Robert Månsson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The development of B cells relies on an intricate network of transcription factors critical for developmental progression and lineage commitment. In the B cell developmental trajectory, a temporal switch from predominant Foxo3 to Foxo1 expression occ
Externí odkaz:
https://doaj.org/article/8607115034c64df893cbadd484c41780
Autor:
Marie E Jönsson, Per Ludvik Brattås, Charlotte Gustafsson, Rebecca Petri, David Yudovich, Karolina Pircs, Shana Verschuere, Sofia Madsen, Jenny Hansson, Jonas Larsson, Robert Månsson, Alexander Meissner, Johan Jakobsson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
DNA methylation plays an important role in silencing transposable elements. Here the authors find that loss of DNMT1 and DNA methylation leads to transcriptional activation and chromatin remodelling of evolutionarily young—hominoid-specific —LINE
Externí odkaz:
https://doaj.org/article/0010acf9352643ada962a4e79869dc29
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-6 (2019)
Abstract Background Chromatin immunoprecipitation coupled to sequencing (ChIP-seq) is widely used to map histone modifications and transcription factor binding on a genome-wide level. Results We present high-throughput ChIPmentation (HT-ChIPmentation
Externí odkaz:
https://doaj.org/article/9867ea83141d4afda198d447edd55d42
Autor:
Tom A. Mulder, Lucía Peña-Pérez, Anna Berglöf, Stephan Meinke, H. Yesid Estupiñán, Kia Heimersson, Rula Zain, Robert Månsson, C. I. Edvard Smith, Marzia Palma
Publikováno v:
HemaSphere, Vol 5, Iss 5, p e564 (2021)
Ibrutinib is a covalently binding inhibitor of the B-cell receptor signaling-mediator Bruton’s tyrosine kinase (BTK) with great efficacy in chronic lymphocytic leukemia (CLL). Common side effects like atrial fibrillation (AF), bleeding and infectio
Externí odkaz:
https://doaj.org/article/7612645b2ec14e5e86e2bbac72791afb