Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Robert J. Fenton"'
Publikováno v:
Microorganisms, Vol 11, Iss 3, p 631 (2023)
Salmonella enterica is, globally, an important cause of human illness with beef being a significant attributable source. In the human patient, systemic Salmonella infection requires antibiotic therapy, and when strains are multidrug resistant (MDR),
Externí odkaz:
https://doaj.org/article/f1d064f42145420d93cf72d8ba166139
Autor:
Govardhan eRathnaiah, Elise A. Lamont, Beth N. Harris, Robert J. Fenton, Denise K. Zinniel, Xiaofei eLiu, Josh eSotos, Zhengyu eFeng, Ayala eLivneh-Kol, Nahum Y. Shpigel, Charles J. Czuprynski, Srinand eSreevastan, Raul G. Barletta
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Mycobacterium avium subsp. paratuberculosis (MAP) is the etiologic agent of Johne’s Disease in ruminants. This enteritis has significant economic impact and worldwide distribution. Vaccination is one of the most cost effective infectious disease co
Externí odkaz:
https://doaj.org/article/3193fc243c8d40648cbcaf6203cf1f64
Autor:
Katie Kenealy, Steven M Halouska, Harpreet K. Chahal, Darrell D. Marshall, Govardhan Rathnaiah, Robert Powers, Robert J. Fenton, Raúl G. Barletta, Denise K. Zinniel
Publikováno v:
Journal of Proteome Research. 16:1270-1279
In mycobacteria, D-alanine is an essential precursor for peptidoglycan biosynthesis. The only confirmed enzymatic pathway to form D-alanine is through the racemization of L-alanine by alanine racemase (Alr, EC 5.1.1.1). Nevertheless, the essentiality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23ae1b9c2288f74bf699ae02f58d3c75
https://doi.org/10.1021/acs.jproteome.6b00871
https://doi.org/10.1021/acs.jproteome.6b00871
Autor:
Darrell D. Marshall, Raúl G. Barletta, Denise K. Zinniel, Steven M Halouska, Robert J. Fenton, Robert Powers
Publikováno v:
Journal of Proteome Research. 13:1065-1076
d-Cycloserine is an effective second line antibiotic used as a last resort to treat multi (MDR)- and extensively (XDR) drug resistant strains of Mycobacterium tuberculosis . d-Cycloserine interferes with the formation of peptidoglycan biosynthesis by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73ee1f6d8f54d14bd8f37455a43a683
https://doi.org/10.1021/pr4010579
https://doi.org/10.1021/pr4010579
Publikováno v:
ACS Chemical Biology. 7:166-171
New strategies are needed to circumvent increasing outbreaks of resistant strains of pathogens and to expand the dwindling supply of effective antimicrobials. A common impediment to drug development is the lack of an easy approach to determine the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b737b9bc64f296934f8dce0a86dba82
https://doi.org/10.1021/cb200348m
https://doi.org/10.1021/cb200348m
Autor:
Avery L. Paulson, Charles J. Czuprynski, John P. Bannantine, Robert J. Fenton, David R. Smith, Raúl G. Barletta, Ofelia Chacon, David Scott McVey, Denise K. Zinniel
Publikováno v:
Clinical and Vaccine Immunology. 18:105-112
Mycobacterium avium subsp. paratuberculosis causes Johne's disease (JD) in ruminants. Development of genetic tools and completion of the M. avium subsp. paratuberculosis genome sequencing project have expanded the opportunities for antigen discovery.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c826893fd15cf4cc98eeb088be3023
https://doi.org/10.1128/cvi.00297-10
https://doi.org/10.1128/cvi.00297-10
Autor:
Robert J. Fenton, Raúl G. Barletta, Ofelia Chacon, Steven M Halouska, Robert Powers, Denise K. Zinniel
Publikováno v:
Journal of Proteome Research. 6:4608-4614
D-Cycloserine (DCS) is only used with multidrug-resistant strains of tuberculosis because of serious side effects. DCS is known to inhibit cell wall biosynthesis, but the in vivo lethal target is still unknown. We have applied NMR-based metabolomics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65ba7e01edf2476a6cbb419b2100e19
https://doi.org/10.1021/pr0704332
https://doi.org/10.1021/pr0704332
Autor:
Peter J. Morley, David Gower, Ian J. Owens, Robert J. Fenton, Anne-Marie Bourgault, Yacine Abed, Guy Boivin, Margaret Tisdale
Publikováno v:
The Journal of Infectious Diseases. 186:1074-1080
Previous studies have shown that amino acid changes in the hemagglutinin (HA) gene of influenza viruses may result in decreased susceptibility to neuraminidase inhibitors (NAIs) in vitro. However, the emergence and characteristics of such HA variants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07579603f0df51b7999a3d7c304c1981
https://doi.org/10.1086/344237
https://doi.org/10.1086/344237
Autor:
N. Beth Harris, Robert J. Fenton, Govardhan Rathnaiah, Xiaofei Liu, Ayala Livneh-Kol, Elise A. Lamont, Denise K. Zinniel, Raúl G. Barletta, Srinand Sreevatsan, Josh Sotos, Zhengyu Feng, Nahum Y. Shpigel, Charles J. Czuprynski
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Mycobacterium avium subsp. paratuberculosis (MAP) is the etiologic agent of Johne's Disease in ruminants. This enteritis has significant economic impact and worldwide distribution. Vaccination is one of the most cost effective infectious disease cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260bb98afb7a200ac172c753a5f18591
http://europepmc.org/articles/PMC4197770
http://europepmc.org/articles/PMC4197770
Autor:
Patrick H. Dussault, Courtney B. Story, Ji-Young Lee, Robert J. Fenton, Wantanee Sittiwong, Robert Powers, Darrell D. Marshall, Bohkyung Kim, Raffll G. Barletta, Denise K. Zinniel
Publikováno v:
ChemMedChem. 9(8)
Eleven fatty acid analogues incorporating four-membered carbocycles (cyclobutenes, cyclobutanes, cyclobutanones, and cyclobutanols) were investigated for the ability to inhibit the growth of Mycobacterium smegmatis (Msm) and Mycobacterium tuberculosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a016607b4809d2798e6a080a352a820
https://pubmed.ncbi.nlm.nih.gov/24902951
https://pubmed.ncbi.nlm.nih.gov/24902951