Zobrazeno 1 - 10
of 2 091
pro vyhledávání: '"Robert Burns"'
Autor:
Moujtaba Y. Kasmani, Paytsar Topchyan, Ashley K. Brown, Ryan J. Brown, Xiaopeng Wu, Yao Chen, Achia Khatun, Donia Alson, Yue Wu, Robert Burns, Chien-Wei Lin, Matthew R. Kudek, Jie Sun, Weiguo Cui
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Influenza virus infection causes increased morbidity and mortality in the elderly. Aging impairs the immune response to influenza, both intrinsically and because of altered interactions with endothelial and pulmonary epithelial cells. To cha
Externí odkaz:
https://doaj.org/article/3316c2e4f76a4dd280e12a2c2ed09272
Autor:
Margherita Rosati, Evangelos Terpos, Philip Homan, Cristina Bergamaschi, Sevasti Karaliota, Ioannis Ntanasis-Stathopoulos, Santhi Devasundaram, Jenifer Bear, Robert Burns, Tina Bagratuni, Ioannis P. Trougakos, Meletios A. Dimopoulos, George N. Pavlakis, Barbara K. Felber
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionCytokines and chemokines play an important role in shaping innate and adaptive immunity in response to infection and vaccination. Systems serology identified immunological parameters predictive of beneficial response to the BNT162b2 mRNA
Externí odkaz:
https://doaj.org/article/ff1d4f55bab147a9957e93a1589ed53e
Autor:
Achia Khatun, Xiaopeng Wu, Fu Qi, Kexin Gai, Arjun Kharel, Matthew R. Kudek, Lisa Fraser, Ashley Ceicko, Moujtaba Y. Kasmani, Amber Majnik, Robert Burns, Yi‐Guang Chen, Nita Salzman, Elizabeth J. Taparowsky, Dayu Fang, Calvin B. Williams, Weiguo Cui
Publikováno v:
Advanced Science, Vol 10, Iss 28, Pp n/a-n/a (2023)
Abstract Regulatory T (Treg) cells are inevitable to prevent deleterious immune responses to self and commensal microorganisms. Treg function requires continuous expression of the transcription factor (TF) FOXP3 and is divided into two major subsets:
Externí odkaz:
https://doaj.org/article/786eb5c93e3443a6b323cd0698684eb8
Autor:
Antonio Valentin, Cristina Bergamaschi, Margherita Rosati, Matthew Angel, Robert Burns, Mahesh Agarwal, Janina Gergen, Benjamin Petsch, Lidia Oostvogels, Edde Loeliger, Kara W. Chew, Steven G. Deeks, James I. Mullins, George N. Pavlakis, Barbara K. Felber
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunogenicity of HIV-1 mRNA vaccine regimens was analyzed in a non-human primate animal model. Rhesus macaques immunized with mRNA in lipid nanoparticle (mRNA/LNP) formulation expressing HIV-1 Gag and Gag conserved regions (CE) as immunogens develop
Externí odkaz:
https://doaj.org/article/b7a5928e7818420ea6f7a20ebbe0d915
Autor:
Cristina Bergamaschi, Maria Pagoni, Margherita Rosati, Matthew Angel, Ifigeneia Tzannou, Margarita Vlachou, Ismini Darmani, Amirah Ullah, Jenifer Bear, Santhi Devasundaram, Robert Burns, Ioannis Baltadakis, Stavros Gigantes, Meletios-Athanasios Dimopoulos, George N. Pavlakis, Evangelos Terpos, Barbara K. Felber
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immunocompromised individuals including patients with hematological malignancies constitute a population at high risk of developing severe disease upon SARS-CoV-2 infection. Protection afforded by vaccination is frequently low and the biology leading
Externí odkaz:
https://doaj.org/article/829c9e52bad24897b4670efd3ea44bb5
Autor:
Silvia Giannini, Melissa M. Lee-Sundlov, Leonardo Rivadeneyra, Christian A. Di Buduo, Robert Burns, Joseph T. Lau, Hervé Falet, Alessandra Balduini, Karin M. Hoffmeister
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Mutations affecting sialylation and galactosylation affect megakaryocyte function and thrombopoiesis. Here the authors show that the enzyme β4GalT1 regulates thrombopoiesis and hematopoietic stem cell homeostasis by controlling beta-1 integrin funct
Externí odkaz:
https://doaj.org/article/260eeeaaa02b43dda46cc8c8f666fa3c
Autor:
Margherita Rosati, Evangelos Terpos, Ioannis Ntanasis-Stathopoulos, Mahesh Agarwal, Jenifer Bear, Robert Burns, Xintao Hu, Eleni Korompoki, Duncan Donohue, David J. Venzon, Meletios-Athanasios Dimopoulos, George N. Pavlakis, Barbara K. Felber
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Durability of SARS-CoV-2 Spike antibody responses after infection provides information relevant to understanding protection against COVID-19 in humans. We report the results of a sequential evaluation of anti-SARS-CoV-2 antibodies in convalescent pat
Externí odkaz:
https://doaj.org/article/741a33df0ccb420fb35607c69fa3b1c0
Autor:
Margherita Rosati, Mahesh Agarwal, Xintao Hu, Santhi Devasundaram, Dimitris Stellas, Bhabadeb Chowdhury, Jenifer Bear, Robert Burns, Duncan Donohue, Laurent Pessaint, Hanne Andersen, Mark G Lewis, Evangelos Terpos, Meletios Athanasios Dimopoulos, Alexander Wlodawer, James I Mullins, David J Venzon, George N Pavlakis, Barbara K Felber
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009701 (2021)
The speed of development, versatility and efficacy of mRNA-based vaccines have been amply demonstrated in the case of SARS-CoV-2. DNA vaccines represent an important alternative since they induce both humoral and cellular immune responses in animal m
Externí odkaz:
https://doaj.org/article/580a4216c5354680995d294b23a456cf