Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Robert, Yan"'
Publikováno v:
EKOMABIS: Jurnal Ekonomi Manajemen Bisnis. 2:125-136
Penelitian ini dilatarbelakangi oleh pertumbuhan bisnis online yang terus maju pesat di era modern saat ini ditandai dengan banyak munculnya pesaing-pesaing baru di dunia bisnis oline (Marketplace). Tujuan penelitian ini untuk mengetahui seberapa pen
Publikováno v:
Frontiers in Molecular Biosciences, Vol 3 (2016)
Iron sulfur clusters are essential universal prosthetic groups which can be formed inorganically but, in biology, are bound to proteins and produced enzymatically. Most of the components of the machine that produces the clusters are conserved through
Externí odkaz:
https://doaj.org/article/0d0f3e4c2b8f45c6855b04959c74b747
The Eukaryotic-Specific ISD11 Is a Complex-Orphan Protein with Ability to Bind the Prokaryotic IscS.
Autor:
Robert Yan, Martin Friemel, Claudia Aloisi, Martijn Huynen, Ian A Taylor, Silke Leimkühler, Annalisa Pastore
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157895 (2016)
The eukaryotic protein Isd11 is a chaperone that binds and stabilizes the central component of the essential metabolic pathway responsible for formation of iron-sulfur clusters in mitochondria, the desulfurase Nfs1. Little is known about the exact ro
Externí odkaz:
https://doaj.org/article/383f1b0605ca43c2a03b62f3736d8f69
Autor:
Dirk J. Duncker, Gavin Whitlock, Kathryn Chapman, Daphne Merkus, Michael D. Schneider, Robert Yan, Charlotte A L Lane, Gary Newton, Maaike te Lintel Hekkert, Rehan Aqil, Darren Cawkill, Trevor Perrior, Robert Downham
Publikováno v:
Basic Research in Cardiology, 116(1):34. D. Steinkopff-Verlag
Reducing infarct size (IS) by interfering with mechanisms for cardiomyocyte death remains an elusive goal. DMX-5804, a selective inhibitor of the stress-activated kinase MAP4K4, suppresses cell death in mouse myocardial infarction (MI), human pluripo
Autor:
Jeffrey Glaser, Ryan Bernhisel, Brent Evans, Robert Yan, Todd M. Morgan, Kirk J. Wojno, Jeremy Lieb, Behfar Ehdaie, Jeffrey Ferguson, Richard E D'Anna, Todd Cohen, Stephanie Meek, Sanjeev Kaul, Steven Stone
Publikováno v:
Personalized Medicine
Aim: To evaluate active surveillance (AS) selection, safety and durability among men with low-risk prostate cancer assessed using the clinical cell cycle risk (CCR) score, a combined clinical and molecular score. Patients & methods: Initial treatment
Autor:
Robert Yan, Salvatore Adinolfi, Clara Iannuzzi, Geoff Kelly, Alain Oregioni, Stephen Martin, Annalisa Pastore
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78948 (2013)
Iron-sulfur clusters are essential protein prosthetic groups that provide their redox potential to several different metabolic pathways. Formation of iron-sulfur clusters is assisted by a specialised machine that comprises, among other proteins, a fe
Externí odkaz:
https://doaj.org/article/657e9f1f40804b90b579f6cd42fa0351
Autor:
Trevor Perrior, Michael D. Schneider, Kathryn L. Chapman, Pelin Arabacilar Golforoush, Sian E. Harding, Elsa Lawrence, Patricia P. Chaves-Guerrero, Robert Yan, Priyanka Narasimhan, Gary Newton
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Given the poor track record to date of animal models for creating cardioprotective drugs, human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) have been proposed as a therapeutically relevant human platform to guide target validation and car
Publikováno v:
Communications Chemistry, Vol 1, Iss 1, Pp 1-7 (2018)
Proteins undergo both cold and heat denaturation, but often cold denaturation cannot be detected because it occurs at temperatures below water freezing. Proteins undergoing detectable cold as well as heat denaturation yield a reliable curve of protei
Publikováno v:
Rasheed, M, Yan, R, Kelly, G & Pastore, A 2017, ' Chemical shift assignment of a thermophile frataxin ', Biomolecular NMR Assignments, pp. 1-4 . https://doi.org/10.1007/s12104-017-9790-3
Biomolecular Nmr Assignments
Biomolecular Nmr Assignments
Frataxin is the protein responsible for the genetically-inherited neurodegenerative disease Friedreich’s ataxia caused by partial silencing of the protein and loss of function. Although the frataxin function is not yet entirely clear, it has been a
Autor:
Priyanka Narasimhan, Dörte Faust, Devika Sanmugalingam, Motoaki Sano, Lorna R. Fiedler, Caroline M. R. Low, Gary Newton, Michela Noseda, Michael D. Schneider, Weihua Song, Marta Abreu Paiva, Daniel J. Stuckey, Sam C. Wang, Rehan Aqil, Tse-Hua Tan, Trevor Perrior, Evie Maifoshie, Lorenzo Pavanello, Micaela Jenkins, George E. Taffet, Mark L. Entman, Sunthar Kanayaganam, Ashley Jarvis, Min Xie, Catherine Tralau-Stewart, Pelin Arabacilar Golforoush, Sian E. Harding, Lloyd H. Michael, Mohamed Bellahcene, Robert D. Sampson, Robert Yan, Mutsuo Harada, Kathryn Chapman, Josef Habib
Publikováno v:
Cell Stem Cell
Heart disease is a paramount cause of global death and disability. Although cardiomyocyte death plays a causal role and its suppression would be logical, no clinical counter-measures target the responsible intracellular pathways. Therapeutic progress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5ff2a02f8c189f051ad5f809c31c17
https://europepmc.org/articles/PMC6458995/
https://europepmc.org/articles/PMC6458995/