Výsledky vyhledávání - "Robert, Wolk"

Akademický článek

Impact of Previous Alopecia Areata Treatment on Efficacy Responses up to Week 48 Following Ritlecitinib Treatment: A Post Hoc Analysis

Autor: Jennifer Fu, Alexander Egeberg, Susan Holmes, Sergio Vano-Galvan, Martin Steinhoff, Roger Edwards, Gianluca Bonfanti, Ranjit Nagra, Robert Wolk, Helen Tran, Ernest Law

Publikováno v: Dermatology and Therapy, Vol 14, Iss 10, Pp 2759-2769 (2024)

Abstract Introduction Patients with alopecia areata (AA) may have received several therapies for management of AA during their lives. In the ALLEGRO phase 2b/3 (NCT03732807) study, the oral JAK3/TEC family kinase inhibitor ritlecitinib demonstrated e

Externí odkaz: https://doaj.org/article/534397c42f1f44fc954995f0c43cc375

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Akademický článek

The Epidemiology of Hospital-Treated Alopecia Areata in Denmark, 1995–2016

Autor: Sissel Brandt Toft Sørensen, Prethibha George, Oladayo Jagun, Robert Wolk, Lynne Napatalung, Samuel H. Zwillich, Lars Iversen, Vera Ehrenstein

Publikováno v: Dermatology and Therapy, Vol 14, Iss 4, Pp 993-1006 (2024)

Abstract Introduction Alopecia areata (AA) is an autoimmune skin disease presenting as nonscarring hair loss. Information on the epidemiology of AA, especially the occurrence of AA and its subtypes within the general population, is scarce. The study

Externí odkaz: https://doaj.org/article/c57380e937764ae587523e55fe6732cd

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Akademický článek

A phase 2a study investigating the effects of ritlecitinib on brainstem auditory evoked potentials and intraepidermal nerve fiber histology in adults with alopecia areata

Autor: Samira Anderson, Guido Cavaletti, Linda J. Hood, Michael Polydefkis, David N. Herrmann, Gary Rance, Brett King, Amy J. McMichael, Maryanne M. Senna, Brian S. Kim, Lynne Napatalung, Robert Wolk, Samuel H. Zwillich, Gregor Schaefer, Yankun Gong, Melanie Sisson, Holly B. Posner

Publikováno v: Pharmacology Research & Perspectives, Vol 12, Iss 4, Pp n/a-n/a (2024)

Abstract Reversible axonal swelling and brainstem auditory evoked potential (BAEP) changes were observed in standard chronic (9‐month) toxicology studies in dogs treated with ritlecitinib, an oral Janus kinase 3/tyrosine kinase expressed in hepatoc

Externí odkaz: https://doaj.org/article/3530c0e1c1d5497d97bb7fe1b83e42ad

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Akademický článek

Hair Loss Profiles and Ritlecitinib Efficacy in Patients with Alopecia Areata: Post Hoc Analysis of the ALLEGRO Phase 2b/3 Study

Autor: Diamant Thaçi, Christos Tziotzios, Taisuke Ito, Justin Ko, Ayşe Serap Karadağ, Hong Fang, Roger A. Edwards, Gianluca Bonfanti, Robert Wolk, Helen Tran, Ernest Law

Publikováno v: Dermatology and Therapy, Vol 13, Iss 11, Pp 2621-2634 (2023)

Abstract Introduction Ritlecitinib demonstrated efficacy in patients with alopecia areata (AA) in the ALLEGRO phase 2b/3 study (NCT03732807). However, hair loss presentation may vary based on location (e.g., scalp, eyebrow/eyelash, body). Here, we so

Externí odkaz: https://doaj.org/article/e5c03365e4f84cdf8ff6a93badf73fd5

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Akademický článek

Incidence Rates of Infections, Malignancies, Thromboembolism, and Cardiovascular Events in an Alopecia Areata Cohort from a US Claims Database

Autor: Prethibha George, Oladayo Jagun, Qing Liu, Charles Wentworth, Lynne Napatalung, Robert Wolk, Susan Anway, Samuel H. Zwillich

Publikováno v: Dermatology and Therapy, Vol 13, Iss 8, Pp 1733-1746 (2023)

Abstract Introduction Alopecia areata (AA) is an autoimmune disease with an underlying immuno-inflammatory pathogenesis. Treatments can include systemic corticosteroids and immunomodulators (such as Janus kinase inhibitors); these medications may be

Externí odkaz: https://doaj.org/article/900481aae67742ffb6245160448662a7

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