Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Robert, Walmsley"'
Publikováno v:
Current Research in Toxicology, Vol 6, Iss , Pp 100167- (2024)
Sunitinib malate is known to cause cardiotoxicity in a sub-population of patients, with heart failure seen in more severe cases. Cardiac progenitor cells (CPCs) have been identified in adult human myocardium and contribute to overall tissue maintenan
Externí odkaz:
https://doaj.org/article/355f9cffb2ab46de90044301e66494da
Autor:
Andrew J. Smith, Prashant Ruchaya, Robert Walmsley, Kathleen E. Wright, Fiona C. Lewis-McDougall, Jacquelyn Bond, Georgina M. Ellison-Hughes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Receptor tyrosine kinase inhibitors improve cancer survival but their cardiotoxicity requires investigation. We investigated these inhibitors’ effects on human cardiac progenitor cells in vitro and rat heart in vivo. We applied imatinib, s
Externí odkaz:
https://doaj.org/article/6ba39ab0a0914d2691c22b3b6ff3747b
Autor:
Robert Walmsley, Derek S. Steele, Georgina M. Ellison-Hughes, Sotiris Papaspyros, Andrew J. Smith
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11812 (2022)
The receptor tyrosine kinase inhibitor imatinib improves patient cancer survival but is linked to cardiotoxicity. This study investigated imatinib’s effects on cell viability, apoptosis, autophagy, and necroptosis in human cardiac progenitor cells
Externí odkaz:
https://doaj.org/article/4e6e8eb78f864ef78c1bb29160ebbf37
Autor:
Hong-Ting Victor Lin, Teresa Massam-Wu, Chen-Ping Lin, Yen-Jen Anna Wang, Yu-Chi Shen, Wen-Jung Lu, Pang-Hung Hsu, Yu-Hou Chen, Maria Ines Borges-Walmsley, Adrian Robert Walmsley
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184255 (2017)
The genome sequence of V. cholerae O1 Biovar Eltor strain N16961 has revealed a putative antibiotic resistance (var) regulon that is predicted to encode a transcriptional activator (VarR), which is divergently transcribed relative to the putative res
Externí odkaz:
https://doaj.org/article/03e7ed1823614df7b0bd7bc860e7d4bf
Autor:
Andrew J, Smith, Prashant, Ruchaya, Robert, Walmsley, Kathleen E, Wright, Fiona C, Lewis-McDougall, Jacquelyn, Bond, Georgina M, Ellison-Hughes
Publikováno v:
Scientific reports. 12(1)
Receptor tyrosine kinase inhibitors improve cancer survival but their cardiotoxicity requires investigation. We investigated these inhibitors' effects on human cardiac progenitor cells in vitro and rat heart in vivo. We applied imatinib, sunitinib or
Publikováno v:
Toxicology in Vitro. 58:178-186
The anti-cancer receptor tyrosine kinase inhibitors include known cardiotoxins: a component of this toxicity may be mediated by effects on cardiac fibroblasts (CFs). We hypothesised that imatinib mesylate (imatinib) and sunitinib malate (sunitinib) c
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11812
The receptor tyrosine kinase inhibitor imatinib mesylate has improved patient cancer survival rates but has been linked to long-term cardiotoxicity. This study investigated the effects of imatinib on cell viability, apoptosis, autophagy and necroptos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c1e2e26bea57a8e1d4bca99ad05af8
https://doi.org/10.1101/2021.04.12.439436
https://doi.org/10.1101/2021.04.12.439436
Autor:
Sir Robert Walmsley
Publikováno v:
The RUSI Journal. 148:25-28
Autor:
Robert Walmsley, David W. Sinclair
Publikováno v:
Clinical Anatomy. 7:305-314
One of the most common congenital abnormalities of the human heart is a defect in the development of the membranous part of the ventricular septum which, in this study, is designated the MVS. The WS is a thin fibrous membrane, about 1 cm long, which
Publikováno v:
Texas Heart Institute journal. 37(2)
Because of the variety of their anatomy and clinical implications, coronary anomalies tend to confuse many observers. Recently, our group and other investigators have proposed that only 1 specific type of anomaly, by means of a specific mechanism, is