Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Robert, Virtala"'
Autor:
Xiaoyun Wang, Dave Singh, Joselyn Rojas-Quintero, Rory A. O'Donnell, Caroline A. Owen, Ratko Djukanovic, Duo Zhang, Robert Virtala, Petra Hazon, Andrew Higham, Jose Miguel Sanchez, Francesca Polverino, Ilyas Yambayev, Henric Olsson, Eva Lindqvist, Donna E. Davies, Susan J. Wilson, Danen Cunoosamy
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 198:1500-1518
Rationale: ADAMs (proteinases with a disintegrin and a metalloproteinase domain) have not been well studied in chronic obstructive pulmonary disease (COPD).Objectives: To investigate whether ADAM9 ...
Autor:
Xiaoyun, Wang, Francesca, Polverino, Joselyn, Rojas-Quintero, Duo, Zhang, José, Sánchez, Ilyas, Yambayev, Eva, Lindqvist, Robert, Virtala, Ratko, Djukanovic, Donna E, Davies, Susan, Wilson, Rory, O'Donnell, Danen, Cunoosamy, Petra, Hazon, Andrew, Higham, Dave, Singh, Henric, Olsson, Caroline A, Owen
Publikováno v:
American journal of respiratory and critical care medicine.
Proteinases with a disintegrin and a metalloproteinase domain (ADAMs) have not been well studied in COPD. We investigated whether ADAM9 is linked to COPD in humans and mice.ADAM9 blood and lung levels were measured in COPD patients versus controls, a
Autor:
Krzysztof Pawłowski, Robert Virtala, Siegbert Warkentin, Ib Groth Clausen, Tim Stevens, Sabina Janciauskiene, Devipriya Subramaniyam
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 40:258-271
Endothelial cells are among the main physiological targets of the pro-inflammatory cytokine tumor necrosis factor-alpha (TNF-alpha). In endothelial cells TNF-alpha elicits a broad spectrum of biological effects including differentiation, proliferatio
Autor:
Lennart Jansson, Susanne Larsson, Sabina Janciauskiene, Robert Virtala, Tim Stevens, Peter Larsson
Publikováno v:
Biochemical and Biophysical Research Communications. 321:592-600
alpha1-Antitrypsin (AAT) is a major circulating and tissue inhibitor of serine proteinases. As such AAT is thought to play an important role in limiting host tissue injury at sites of inflammation. There is now increasing evidence, however, that AAT
Publikováno v:
British Journal of Haematology. 106:627-633
High level of lung resistance related protein mRNA in leukaemic cells from patinets with acute myelogenous leukaemia are associated with inferior response to chemotherapy and prior treatment with mitoxantrone.
Autor:
Robert Virtala, Elisabet Wieslander, Rory A. O'Donnell, Ratko Djukanovic, Per Broberg, Stephen T. Holgate, Sebastian Möller, Per Erik Strömstedt, Gilbert Angco, Audrey Richter, Håkan Bergstrand, Eva Lindqvist, Donna E. Davies, Susan J. Wilson, Krzysztof Pawłowski, Witte Koopmann, Stefan Pierrou, Johan Lund
Publikováno v:
American journal of respiratory and critical care medicine. 175(6)
The molecular mechanisms involved in airway oxidative stress responses reported in healthy smokers and in those with chronic obstructive pulmonary disease (COPD) are poorly understood.To assess the expression of genes involved in oxidative stress res
Autor:
Martin R. Stämpfli, Naila Svitacheva, Kerstin Thim, Maria Lindahl, John D. Taylor, Per Ola Önnervik, Amir Smailagic, Robert Virtala
Publikováno v:
Inflammation Research
Objective The aim was to create pathological changes in mice relevant to human smoke exposure that can be used to further understand the mechanisms and pathology of smoke-induced inflammatory disease. Methods Mice were exposed to tobacco smoke or lip