Zobrazeno 1 - 10
of 707
pro vyhledávání: '"Robert, Thimme"'
Autor:
Julius Mueller, Valentin Miedtke, Armin Kuellmer, Moritz Schiemer, Dominik Bettinger, Robert Thimme, Arthur Schmidt
Publikováno v:
Endoscopy International Open, Vol 12, Iss 08, Pp E989-E995 (2024)
Externí odkaz:
https://doaj.org/article/44aa6a2a321e4cb396145e4bc2f031b5
Autor:
Lukas Sturm, Misa Hirose, Laura Stolz, Michael Schultheiss, Katharina Zoldan, Marlene Reincke, Jan Patrick Huber, Rafael Kaeser, Tobias Boettler, Robert Thimme, Elisabeth Albert, Hauke Busch, Axel Künstner, Dominik Bettinger
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Recent studies have linked proton pump inhibitor (PPI) treatment to increased complications of cirrhosis, such as bacterial infections and hepatic encephalopathy. However, the underlying pathophysiological mechanisms remain unclear. The pres
Externí odkaz:
https://doaj.org/article/e841650409eb40b89821619cd8c12ecb
Autor:
Martin Rössle, Dominik Bettinger, Lukas Sturm, Marlene Reincke, Robert Thimme, Michael Schultheiss
Publikováno v:
Diagnostics, Vol 14, Iss 3, p 344 (2024)
Hepatic vein outflow obstruction causes congestion of the liver, leading to necrosis, fibrosis, and portal hypertension (PH). A transjugular intrahepatic portosystemic shunt (TIPS) reduces congestion and PH by providing artificial outflow. The aim of
Externí odkaz:
https://doaj.org/article/319bf1ea9234460cb5f86455136b54a0
Autor:
Zhen Zhang, David Rafei-Shamsabadi, Saskia Lehr, Nico Buettner, Rebecca Diehl, Daniela Huzly, David J Pinato, Robert Thimme, Frank Meiss, Bertram Bengsch
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background and Aims Dual immune checkpoint blockade (ICB) therapy can result in immune-related-adverse events (irAE) such as ICB-hepatitis. An expansion of effector-memory (TEM) CD4 T cells associated with antiviral immunity against herpesvi
Externí odkaz:
https://doaj.org/article/b860d8c6c19d4e1bb749ee5eb4e24d49
Autor:
Marlene Reincke, Michael Schultheiss, Michael Doppler, Niklas Verloh, Wibke Uller, Lukas Sturm, Robert Thimme, Christian Goetz, Dominik Bettinger
Publikováno v:
Hepatology Communications, Vol 6, Iss 11, Pp 3223-3233 (2022)
Abstract Transarterial radioembolization (TARE) is a well‐established therapy for intermediate and advanced tumor stages of hepatocellular carcinoma (HCC). Treatment‐associated toxicities are rare. Previous studies have outlined that the prognosi
Externí odkaz:
https://doaj.org/article/fc2d6b8e2c4c4d62b05d7cfe2baae433
Autor:
Matthias Reinscheid, Hendrik Luxenburger, Vivien Karl, Anne Graeser, Sebastian Giese, Kevin Ciminski, David B. Reeg, Valerie Oberhardt, Natascha Roehlen, Julia Lang-Meli, Kathrin Heim, Nina Gross, Christina Baum, Siegbert Rieg, Claudius Speer, Florian Emmerich, Susanne Breisinger, Daniel Steinmann, Bertram Bengsch, Tobias Boettler, Georg Kochs, Martin Schwemmle, Robert Thimme, Christoph Neumann-Haefelin, Maike Hofmann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Vaccines induce beneficial immunity for COVID-19, but immune waning prompts boosting vaccination. Here, the authors show that a third, boosting dose of COVID-19 mRNA vaccine induces transient CD8 + T effector cell response while conserving the CD8 me
Externí odkaz:
https://doaj.org/article/fca8aca08c224586bb686b0fe9b5ffd3
Autor:
Christopher Dietz-Fricke, Frank Tacke, Caroline Zöllner, Münevver Demir, Hartmut H. Schmidt, Christoph Schramm, Katharina Willuweit, Christian M. Lange, Sabine Weber, Gerald Denk, Christoph P. Berg, Julia M. Grottenthaler, Uta Merle, Alexander Olkus, Stefan Zeuzem, Kathrin Sprinzl, Thomas Berg, Florian van Bömmel, Johannes Wiegand, Toni Herta, Thomas Seufferlein, Eugen Zizer, Nektarios Dikopoulos, Robert Thimme, Christoph Neumann-Haefelin, Peter R. Galle, Martin Sprinzl, Ansgar W. Lohse, Julian Schulze zur Wiesch, Jan Kempski, Andreas Geier, Florian P. Reiter, Bernhard Schlevogt, Juliana Gödiker, Wolf Peter Hofmann, Peter Buggisch, Julia Kahlhöfer, Kerstin Port, Benjamin Maasoumy, Markus Cornberg, Heiner Wedemeyer, Katja Deterding
Publikováno v:
JHEP Reports, Vol 5, Iss 4, Pp 100686- (2023)
Background & Aims: Bulevirtide is a first-in-class entry inhibitor of hepatitis B surface antigen. In July 2020, bulevirtide was conditionally approved for the treatment of hepatitis D, the most severe form of viral hepatitis, which frequently causes
Externí odkaz:
https://doaj.org/article/25235c3dba9540059b007583dc50c8da
Autor:
Asala Nassar, Jan Patrick Huber, Daniela Stallmann, Diana Sharipova, Muataz Ali Hamad, Michael Schultheiss, Robert Thimme, Daniel Duerschmied, Rüdiger Eberhard Scharf, Dominik Bettinger, Krystin Krauel
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2057 (2023)
Transjugular intrahepatic portosystemic shunt (TIPS) implantation is an effective treatment of portal hypertension in patients with decompensated liver cirrhosis. However, some patients develop TIPS thrombosis with recurrence of portal hypertension.
Externí odkaz:
https://doaj.org/article/58c0e53e9e094c6983ddcd220e00dba6
Autor:
Sebastian Weigang, Jonas Fuchs, Gert Zimmer, Daniel Schnepf, Lisa Kern, Julius Beer, Hendrik Luxenburger, Jakob Ankerhold, Valeria Falcone, Janine Kemming, Maike Hofmann, Robert Thimme, Christoph Neumann-Haefelin, Svenja Ulferts, Robert Grosse, Daniel Hornuss, Yakup Tanriver, Siegbert Rieg, Dirk Wagner, Daniela Huzly, Martin Schwemmle, Marcus Panning, Georg Kochs
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Here, in a longitudinal case study, Weigang et al. demonstrate that evolution of SARS-CoV-2 within a persistently infected immunosuppressed patient can result in the emergence of novel variants with reduced sensitivity to antibody neutralization.
Externí odkaz:
https://doaj.org/article/fb1ea91842db4a2381c73359e44031ee
Autor:
Katharina Wild, Maike Smits, Saskia Killmer, Shirin Strohmeier, Christoph Neumann-Haefelin, Bertram Bengsch, Florian Krammer, Martin Schwemmle, Maike Hofmann, Robert Thimme, Katharina Zoldan, Tobias Boettler
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Understanding individual variations in the response to seasonal influenza vaccines has broad implications from basic immunology to public health. Here authors show that influenza hemagglutinin-specific T and B cell responses are determined by the pre
Externí odkaz:
https://doaj.org/article/5ecdcebcaf7d4d5180dbe8bfd157f337