Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Robert, Para"'
Autor:
Valeria Garcia-Flores, Roberto Romero, Yi Xu, Kevin R. Theis, Marcia Arenas-Hernandez, Derek Miller, Azam Peyvandipour, Gaurav Bhatti, Jose Galaz, Meyer Gershater, Dustyn Levenson, Errile Pusod, Li Tao, David Kracht, Violetta Florova, Yaozhu Leng, Kenichiro Motomura, Robert Para, Megan Faucett, Chaur-Dong Hsu, Gary Zhang, Adi L. Tarca, Roger Pique-Regi, Nardhy Gomez-Lopez
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
As pregnant women are considered vulnerable to SARSCoV-2 infection, it is important to investigate the actual risks involved. The authors show here that, while a T cell-dominant inflammatory response is observed at the maternal-foetal interface, the
Externí odkaz:
https://doaj.org/article/563f7c1a952d4790836162c3fee12855
Autor:
Roger Pique-Regi, Roberto Romero, Valeria Garcia-Flores, Azam Peyvandipour, Adi L. Tarca, Errile Pusod, Jose Galaz, Derek Miller, Gaurav Bhatti, Robert Para, Tomi Kanninen, Ola Hadaya, Carmen Paredes, Kenichiro Motomura, Jeffrey R. Johnson, Eunjung Jung, Chaur-Dong Hsu, Stanley M. Berry, Nardhy Gomez-Lopez
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
Parturition is a well-orchestrated process characterized by increased uterine contractility, cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a quiescent to a contractile myometrium heralds the onset of labo
Externí odkaz:
https://doaj.org/article/ac30acf76d3d49038f011b290fd74251
Autor:
Kenichiro Motomura, Roberto Romero, Yi Xu, Kevin R. Theis, Jose Galaz, Andrew D. Winters, Rebecca Slutsky, Valeria Garcia-Flores, Chengrui Zou, Dustyn Levenson, Robert Para, Madison M. Ahmad, Derek Miller, Chaur-Dong Hsu, Nardhy Gomez-Lopez
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Intra-amniotic infection is strongly associated with adverse pregnancy and neonatal outcomes. Most intra-amniotic infections are due to Ureaplasma species; however, the pathogenic potency of these genital mycoplasmas to induce preterm birth
Externí odkaz:
https://doaj.org/article/376ac8970ef1425d8420cfdeec6b82f6
Autor:
Nardhy Gomez-Lopez, Roberto Romero, Li Tao, Meyer Gershater, Yaozhu Leng, Chengrui Zou, Marcelo Farias-Jofre, Jose Galaz, Derek Miller, Adi L. Tarca, Marcia Arenas-Hernandez, Gaurav Bhatti, Valeria Garcia-Flores, Zhenjie Liu, Robert Para, Tomi Kanninen, Ola Hadaya, Carmen Paredes, Yi Xu
Publikováno v:
J Immunol
Pregnant women are at increased risk of adverse outcomes, including preeclampsia and preterm birth, that may result from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Pregnancy imprints specific maternal immune responses tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce89fcdb262750c22471e3a2cfa29c36
https://doi.org/10.4049/jimmunol.2101123
https://doi.org/10.4049/jimmunol.2101123
Autor:
Roberto Romero, Nardhy Gomez-Lopez, Robert Para, Chaur-Dong Hsu, Percy Pacora, Jose Galaz, Marian Kacerovsky, Bogdan Panaitescu, Kenichiro Motomura, Rebecca Slutsky, Yi Xu
Publikováno v:
J Perinat Med
Background Preterm birth is the leading cause of perinatal morbidity and mortality. Preterm prelabor rupture of membranes (pPROM) occurs in 30% of preterm births; thus, this complication is a major contributor to maternal and neonatal morbidity. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37079f74cf7c96352a16eeec343051c
https://doi.org/10.1515/jpm-2019-0395
https://doi.org/10.1515/jpm-2019-0395
Autor:
Robert Para, Roger Pique-Regi, Eun Jung Jung, Roberto Romero, Derek Miller, Adi L. Tarca, Jenna Isherwood, Meyer Gershater, Tomi Kanninen, Azam Peyvandipour, Li Tao, Kenichiro Motomura, Jose Galaz, Nardhy Gomez-Lopez, Douglas M. Ruden, Bogdan Done
Publikováno v:
Immunohorizons
Fetal inflammatory response syndrome (FIRS) is strongly associated with neonatal morbidity and mortality and can be classified as type I or type II. Clinically, FIRS type I and type II are considered as distinct syndromes, yet the molecular underpinn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a44f6fcc414a872658f6d255d822f5
https://europepmc.org/articles/PMC9394103/
https://europepmc.org/articles/PMC9394103/
Autor:
Nardhy Gomez-Lopez, Roberto Romero, Derek Miller, Chaur-Dong Hsu, Jose Galaz, Marian Kacerovsky, Rebecca Slutsky, Aneesha Varrey, Robert Para, Kenichiro Motomura, Dustyn Levenson, Andrew D. Winters, Percy Pacora, Kevin R. Theis, Violetta Florova
Publikováno v:
J Perinat Med
Background Intra-amniotic inflammation, which is associated with adverse pregnancy outcomes, can occur in the presence or absence of detectable microorganisms, and involves activation of the inflammasome. Intra-amniotic inflammasome activation has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc0d140ae7bd4d5b0c52c4292e463058
https://doi.org/10.1515/jpm-2019-0398
https://doi.org/10.1515/jpm-2019-0398
Autor:
Roberto Romero, Nardhy Gomez-Lopez, Adi L. Tarca, Chaur-Dong Hsu, Percy Pacora, Chengrui Zou, Derek Miller, Bogdan Panaitescu, Robert Para, Sonia S. Hassan, Dereje W. Gudicha
Publikováno v:
The Journal of Maternal-Fetal & Neonatal Medicine. 34:569-579
Objective: Pyroptosis is an inflammatory form of programmed cell death that is mediated by the activation of the inflammasome and depends on the pore-forming function of gasdermin D. Therefore, the...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4f96d2a613073249d5e215a50ecc0ad
https://doi.org/10.1080/14767058.2019.1610740
https://doi.org/10.1080/14767058.2019.1610740
Autor:
Nardhy Gomez-Lopez, Roberto Romero, Jose Galaz, Robert Para, Bogdan Panaitescu, Marcia Arenas-Hernandez
Publikováno v:
J Perinat Med
Objectives Preterm birth remains the leading cause of perinatal morbidity and mortality worldwide. Preterm birth is preceded by spontaneous preterm labor, which is commonly associated with sterile intra-amniotic inflammation; yet, no approved treatme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6e4e84d47b58fc1863b056d6e96019
https://europepmc.org/articles/PMC8440410/
https://europepmc.org/articles/PMC8440410/
Autor:
David Kmak, Roberto Romero, Jeffrey Johnson, Bo Hyun Yoon, Robert Para, Tinnakorn Chaiworapongsa, Lami Yeo, Eun Jung Jung, Chaur-Dong Hsu
Publikováno v:
J Matern Fetal Neonatal Med
Cervical insufficiency generally refers to a condition in which there is mid-trimester cervical dilatation or protruding chorioamniotic membranes in the absence of uterine contractions. Such condition is a risk factor for spontaneous mid-trimester ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4bc199d0464e46a0e1d698a482eb4cf
https://europepmc.org/articles/PMC8521637/
https://europepmc.org/articles/PMC8521637/