Zobrazeno 1 - 10
of 414
pro vyhledávání: '"Robert, Paine"'
Autor:
Theodore G. Liou, Natalia Argel, Fadi Asfour, Perry S. Brown, Barbara A. Chatfield, David R. Cox, Cori L. Daines, Dixie Durham, Jessica A. Francis, Barbara Glover, My Helms, Theresa Heynekamp, John R. Hoidal, Judy L. Jensen, Christiana Kartsonaki, Ruth Keogh, Carol M. Kopecky, Noah Lechtzin, Yanping Li, Jerimiah Lysinger, Osmara Molina, Craig Nakamura, Kristyn A. Packer, Robert Paine, III, Katie R. Poch, Alexandra L. Quittner, Peggy Radford, Abby J. Redway, Scott D. Sagel, Rhonda D. Szczesniak, Shawna Sprandel, Jennifer L. Taylor-Cousar, Jane B. Vroom, Ryan Yoshikawa, John P. Clancy, J. Stuart Elborn, Kenneth N. Olivier, Frederick R. Adler
Publikováno v:
iScience, Vol 27, Iss 3, Pp 108835- (2024)
Summary: Airway inflammation underlies cystic fibrosis (CF) pulmonary exacerbations. In a prospective multicenter study of randomly selected, clinically stable adolescents and adults, we assessed relationships between 24 inflammation-associated molec
Externí odkaz:
https://doaj.org/article/0b6e6acfca2f4e87b4dbc09bc0ef7656
Autor:
Kristi J. Warren, Emily M. Beck, Sean J. Callahan, My N. Helms, Elizabeth Middleton, Sean Maddock, Jason R. Carr, Dixie Harris, Denitza P. Blagev, Michael J. Lanspa, Samuel M. Brown, Robert Paine
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Exposure to e-cigarette vapors alters important biologic processes including phagocytosis, lipid metabolism, and cytokine activity in the airways and alveolar spaces. Little is known about the biologic mechanisms underpinning the conversion
Externí odkaz:
https://doaj.org/article/d62237b9698b4213a647b3386363745c
Autor:
Katarina M. DiLillo, Katy C. Norman, Christine M. Freeman, Stephanie A. Christenson, Neil E. Alexis, Wayne H. Anderson, Igor Z. Barjaktarevic, R. Graham Barr, Alejandro P. Comellas, Eugene R. Bleecker, Richard C. Boucher, David J. Couper, Gerard J. Criner, Claire M. Doerschuk, J. Michael Wells, MeiLan K. Han, Eric A. Hoffman, Nadia N. Hansel, Annette T. Hastie, Robert J. Kaner, Jerry A. Krishnan, Wassim W. Labaki, Fernando J. Martinez, Deborah A. Meyers, Wanda K. O’Neal, Victor E. Ortega, Robert Paine, Stephen P. Peters, Prescott G. Woodruff, Christopher B. Cooper, Russell P. Bowler, Jeffrey L. Curtis, Kelly B. Arnold, SPIROMICS investigators
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Accelerated progression of chronic obstructive pulmonary disease (COPD) is associated with increased risks of hospitalization and death. Prognostic insights into mechanisms and markers of progression could facilitate development of disease-m
Externí odkaz:
https://doaj.org/article/44f990fcab4543089c5321fad16440df
Autor:
Kristi J. Warren, Cassandra Deering-Rice, Tom Huecksteadt, Shubhanshi Trivedi, Alessandro Venosa, Christopher Reilly, Karl Sanders, Frederic Clayton, Todd A. Wyatt, Jill A. Poole, Nicola M. Heller, Daniel Leung, Robert Paine
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-17 (2023)
Highlights Steady levels of estrogen are associated with changes in allergic inflammation. When E2 is maintained at a level comparable to the mid-follicular phase of ovulation mucus production and airway hyperreactivity are increased. Estrogen reduce
Externí odkaz:
https://doaj.org/article/aae9a7bfdacf4c79abae740cad18bcf2
Autor:
Chaudhary, Muhammad F A, Hoffman, Eric A, Guo, Junfeng, Comellas, Alejandro P, Newell, John D, Jr, Nagpal, Prashant, Fortis, Spyridon, Christensen, Gary E, Gerard, Sarah E, Pan, Yue, Wang, Di, Abtin, Fereidoun, Barjaktarevic, Igor Z, Barr, R Graham, Bhatt, Surya P, Bodduluri, Sandeep, Cooper, Christopher B, Gravens-Mueller, Lisa, Han, MeiLan K, Kazerooni, Ella A, Martinez, Fernando J, Menchaca, Martha G, Ortega, Victor E, III, Robert Paine, Schroeder, Joyce D, Woodruff, Prescott G, Reinhardt, Joseph M *
Publikováno v:
In The Lancet Digital Health February 2023 5(2):e83-e92
Autor:
Vickram Tejwani, Han Woo, Chen Liu, Anna K. Tillery, Amanda J. Gassett, Richard E. Kanner, Eric A. Hoffman, Fernando J. Martinez, Prescott G. Woodruff, R. Graham Barr, Ashraf Fawzy, Kirsten Koehler, Jeffrey L. Curtis, Christine M. Freeman, Christopher B. Cooper, Alejandro P. Comellas, Cheryl Pirozzi, Robert Paine, Donald Tashkin, Jerry A. Krishnan, Coralynn Sack, Nirupama Putcha, Laura M. Paulin, Marina Zusman, Joel D. Kaufman, Neil E. Alexis, Nadia N. Hansel
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Airway macrophages (AM), crucial for the immune response in chronic obstructive pulmonary disease (COPD), are exposed to environmental particulate matter (PM), which they retain in their cytoplasm as black carbon (BC). However, wh
Externí odkaz:
https://doaj.org/article/560d7cf59df54945adb8be143473ac12
Autor:
Peter Michaely, Suzette J. Bielinski, Kenneth Campbell, Franco D’Alessio, Delphine Dean, Yumei Feng Earley, Robert Paine, Guy Salama, Inga Peter
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
The National Institutes of Health’s (NIH) K99/R00 Pathway to Independence Award offers promising postdoctoral researchers and clinician-scientists an opportunity to receive research support at both the mentored and the independent levels with the g
Externí odkaz:
https://doaj.org/article/2d844935dc2244a69e4c590af7f05055
Autor:
Hillard M. Lazarus, Katherine Pitts, Tisha Wang, Elinor Lee, Elizabeth Buchbinder, Michael Dougan, David G. Armstrong, Robert Paine, Carolyn E. Ragsdale, Timothy Boyd, Edwin P. Rock, Robert Peter Gale
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionEndogenous granulocyte-macrophage colony-stimulating factor (GM-CSF), identified by its ability to support differentiation of hematopoietic cells into several types of myeloid cells, is now known to support maturation and maintain the met
Externí odkaz:
https://doaj.org/article/628d7532ee3142388262f636c3a91400
Autor:
Tong Zhang, Nicholas J. Day, Matthew Gaffrey, Karl K. Weitz, Kwame Attah, Patrice N. Mimche, Robert Paine, III, Wei-Jun Qian, My N. Helms
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102405- (2022)
Preterm infants and patients with lung disease often have excess fluid in the lungs and are frequently treated with oxygen, however long-term exposure to hyperoxia results in irreversible lung injury. Although the adverse effects of hyperoxia are med
Externí odkaz:
https://doaj.org/article/0d8fda8689d44b0fa3425dcdb556e9d9
Autor:
Silva Kasela, Victor E. Ortega, Molly Martorella, Suresh Garudadri, Jenna Nguyen, Elizabeth Ampleford, Anu Pasanen, Srilaxmi Nerella, Kristina L. Buschur, Igor Z. Barjaktarevic, R. Graham Barr, Eugene R. Bleecker, Russell P. Bowler, Alejandro P. Comellas, Christopher B. Cooper, David J. Couper, Gerard J. Criner, Jeffrey L. Curtis, MeiLan K. Han, Nadia N. Hansel, Eric A. Hoffman, Robert J. Kaner, Jerry A. Krishnan, Fernando J. Martinez, Merry-Lynn N. McDonald, Deborah A. Meyers, Robert Paine, Stephen P. Peters, Mario Castro, Loren C. Denlinger, Serpil C. Erzurum, John V. Fahy, Elliot Israel, Nizar N. Jarjour, Bruce D. Levy, Xingnan Li, Wendy C. Moore, Sally E. Wenzel, Joe Zein, NHLBI SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS), NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Charles Langelier, Prescott G. Woodruff, Tuuli Lappalainen, Stephanie A. Christenson
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)
Abstract Background The large airway epithelial barrier provides one of the first lines of defense against respiratory viruses, including SARS-CoV-2 that causes COVID-19. Substantial inter-individual variability in individual disease courses is hypot
Externí odkaz:
https://doaj.org/article/87ab72a86e144f1c976576cc59d3efd7