Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Robert, O'Hagan"'
Autor:
Robert O'Hagan, Irini Topalidou
Publikováno v:
Bio-Protocol, Vol 11, Iss 19 (2021)
Although the advent of genetically-encoded fluorescent markers, such as the green fluorescent protein (GFP; Chalfie et al., 1994), has enabled convenient visualization of gene expression in vivo, this method is generally not effective for detecting p
Externí odkaz:
https://doaj.org/article/289bbaa4f7014e7dba2a99e2b68b391c
Autor:
Kade M Power, Jyothi S Akella, Amanda Gu, Jonathon D Walsh, Sebastian Bellotti, Margaret Morash, Winnie Zhang, Yasmin H Ramadan, Nicole Ross, Andy Golden, Harold E Smith, Maureen M Barr, Robert O'Hagan
Publikováno v:
PLoS Genetics, Vol 16, Iss 10, p e1009052 (2020)
Ciliary microtubules are subject to post-translational modifications that act as a "Tubulin Code" to regulate motor traffic, binding proteins and stability. In humans, loss of CCP1, a cytosolic carboxypeptidase and tubulin deglutamylating enzyme, cau
Externí odkaz:
https://doaj.org/article/c31953d4b8684ae9b72f982eed9b6462
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 4, Pp 1121-1130 (2016)
The Caenorhabditis elegans DEG/ENaC proteins MEC-4 and MEC-10 transduce gentle touch in the six touch receptor neurons . Gain-of-function mutations of mec-4 and mec-4(d) result in a hyperactive channel and neurodegeneration in vivo. Loss of MEC-6, a
Externí odkaz:
https://doaj.org/article/90645747ecc446a19a4c778da4587ab0
Autor:
Yasmin H. Ramadan, Robert O'Hagan, Amanda Gu, Bonnie L. Firestein, Sara A. McEwan, Nicole Ross, Maureen M. Barr
Publikováno v:
eNeuro
Microtubules (MTs) are cytoskeletal elements that provide structural support and act as roadways for intracellular transport in cells. MTs are also needed for neurons to extend and maintain long axons and dendrites that establish connectivity to tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81205ee590a7d2247f4e09add8606597
https://pubmed.ncbi.nlm.nih.gov/33688040
https://pubmed.ncbi.nlm.nih.gov/33688040
Community forestry has long been regarded as a way to achieve the sustainable management of forest and tree resources while maximizing benefits for those responsible for the custodianship of natural resources. Throughout much of the developing world,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::490b1c97df97c405a56222d287e48c7a
https://doi.org/10.1017/9781108684439.013
https://doi.org/10.1017/9781108684439.013
Autor:
Nicole Ross, Amanda Gu, Harold E. Smith, Sebastian Bellotti, Margaret Morash, Andy Golden, Jonathon D. Walsh, Jyothi S. Akella, Maureen M. Barr, Winne Zhang, Kade M. Power, Robert O'Hagan
Ciliary microtubules are subject to post-translational modifications that act as a “Tubulin Code” to regulate motor traffic, binding proteins and stability. In humans, loss of CCP1, a cytosolic carboxypeptidase and tubulin deglutamylating enzyme,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b81f72aa1aaf09bdcc89eb089e016a0c
https://doi.org/10.1101/2020.05.21.108449
https://doi.org/10.1101/2020.05.21.108449
Autor:
Robert O'Hagan, Dean Lockhead, Paul W. Sternberg, Alexander R. Dunn, Sebastian Bellotti, Erich M. Schwarz, Miriam B. Goodman, Maureen M. Barr, Michael Krieg
Publikováno v:
Molecular Biology of the Cell. 27:3717-3728
Microtubules contribute to many cellular processes, including transport, signaling, and chromosome separation during cell division (Kapitein and Hoogenraad, 2015). They are comprised of αβ‐tubulin heterodimers arranged into linear protofilaments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f6c8d76ec6f635429b1483c2c2b3e8f
https://doi.org/10.1091/mbc.e16-06-0473
https://doi.org/10.1091/mbc.e16-06-0473
Autor:
Robert O'Hagan, David H. Hall, Malan Silva, Winnie Zhang, Sebastian Bellotti, Maureen M. Barr, Ken C. Q. Nguyen, Yasmin H. Ramadan
Publikováno v:
Current biology : CB. 27(22)
Summary Ciliary microtubules (MTs) are extensively decorated with post-translational modifications (PTMs), such as glutamylation of tubulin tails. PTMs and tubulin isotype diversity act as a "tubulin code" that regulates cytoskeletal stability and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc101ce7bda22791cac46168ed83425b
https://pubmed.ncbi.nlm.nih.gov/29129530
https://pubmed.ncbi.nlm.nih.gov/29129530
Publikováno v:
Seminars in Cell & Developmental Biology. 33:25-33
The investigation of Caenorhabditis elegans males and the male-specific sensory neurons required for mating behaviors has provided insight into the molecular function of polycystins and mechanisms that are needed for polycystin ciliary localization.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3278642db51d92b20953df0b1f594041
https://doi.org/10.1016/j.semcdb.2014.06.001
https://doi.org/10.1016/j.semcdb.2014.06.001
Autor:
Robert O'Hagan, Maureen M. Barr
Publikováno v:
Nature Cell Biology. 17:1517-1519
A powerful combination of two-colour imaging in vivo, Fourier-filtered kymography and simulations provides a high-resolution view of kinesin-2 transport dynamics in cilia. This study reveals heterotrimeric kinesin-II as an 'obstacle-course runner' an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfac045c9e361e03f3ea1fc3334c848
https://doi.org/10.1038/ncb3279
https://doi.org/10.1038/ncb3279