Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Robert, Kolodziejczyk"'
Autor:
Robert Kolodziejczyk, Kornelia M Mikula, Tommi Kotila, Vincent L G Postis, T Sakari Jokiranta, Adrian Goldman, Taru Meri
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188127 (2017)
Complement is an important part of innate immunity. The alternative pathway of complement is activated when the main opsonin, C3b coats non-protected surfaces leading to opsonisation, phagocytosis and cell lysis. The alternative pathway is tightly co
Externí odkaz:
https://doaj.org/article/edfce245bbc5411c85a413b7561c3500
Autor:
Janusz Wisniewski, Mariusz Jaskolski, Kamil Szpotkowski, Andrzej Dzugaj, J. Barciszewski, Robert Kolodziejczyk, Dariusz Rakus
Publikováno v:
Acta Biochimica Polonica.
Muscle fructose-1,6-bisphosphatase (FBPase), which catalyzes the hydrolysis of fructose-1,6-bisphosphate (F1,6BP) to fructose-6-phosphate (F6P) and inorganic phosphate, regulates glucose homeostasis by controlling the glyconeogenic pathway. FBPase re
Publikováno v:
Journal of Structural Biology
Graphical abstract
Highlights • UspA1299–452 is a left-handed coiled-coil structure that follows TAA rules. • Structure of UspA1299–452 contains part of the long neck domain and of the stalk. • UspA1-C3d binding does not saturate at C3
Highlights • UspA1299–452 is a left-handed coiled-coil structure that follows TAA rules. • Structure of UspA1299–452 contains part of the long neck domain and of the stalk. • UspA1-C3d binding does not saturate at C3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c4afb445d2ff62bb9a6b7e580c96c0
Autor:
Robert Kolodziejczyk, J. Barciszewski, Andrzej Dzugaj, Mariusz Jaskolski, Dariusz Rakus, Janusz Wisniewski
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
When crystallized in the absence of the allosteric inhibitor AMP, human muscle fructose-1,6-bisphosphatase has a totally unexpected quaternary structure of its active R form, with the two dimers of the homotetrameric molecule in a perpendicular orien
Insect Juvenile Hormone Binding Protein Shows Ancestral Fold Present in Human Lipid-Binding Proteins
Autor:
Andrzej Ożyhar, Grzegorz Bujacz, Robert Kolodziejczyk, Michał Jakób, Mariusz Jaskolski, Marian Kochman
Publikováno v:
Journal of Molecular Biology. 377:870-881
Low molecular weight juvenile hormone binding proteins (JHBPs) are specific carriers of juvenile hormone (JH) in the hemolymph of butterflies and moths. As hormonal signal transmitters, these proteins exert a profound effect on insect development. Th
Autor:
T. Sakari Jokiranta, Harald Seeberger, Mihály Józsi, Arnab Bhattacharjee, Adrian Goldman, Robert Kolodziejczyk, Zoltán Prohászka, Barbara Uzonyi, Stefanie Reuter, Eszter Trojnár, Ágnes Szilágyi, Satu Hyvärinen
Publikováno v:
The Journal of Biological Chemistry
Background: It is unknown why patients with autoantibodies against complement factor H (CFH) lack homologous CFHR1 protein. Results: The autoantibody epitope on CFH was identified, and the structure of the corresponding part of CFHR1 was solved. Conc
Autor:
Michal Dadlez, Marian Kochman, Andrzej Ożyhar, Anna Lalik, Janusz Debski, Aleksandra Wysłouch-Cieszyńska, Robert Kolodziejczyk, Krystyna Grzelak, Barbara Kludkiewicz
Publikováno v:
Archives of Biochemistry and Biophysics. 421:260-266
The juvenile hormone binding protein (JHBP) from Galleria mellonella hemolymph is a glycoprotein composed of 225 amino acid residues. It contains four Cys residues forming two disulfide bridges. In this study, the topography of the disulfide bonds as
Autor:
Jesper S. Oeemig, T. Sakari Jokiranta, Adrian Goldman, Hideo Iwaï, Arnab Bhattacharjee, Markus J. Lehtinen, Robert Kolodziejczyk, Taru Meri, Tommi Kajander
Publikováno v:
ResearcherID
Borrelia burgdorferi spirochetes that cause Lyme borreliosis survive for a long time in human serum because they successfully evade the complement system, an important arm of innate immunity. The outer surface protein E (OspE) of B. burgdorferi is ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167a94d2fd74da34dda36f94b72d5c2d
https://europepmc.org/articles/PMC3696643/
https://europepmc.org/articles/PMC3696643/
Autor:
Ewa Maciaszczyk-Dziubinska, Robert W. Wysocki, Andrzej Dzugaj, Marek Zarzycki, Mariusz Jaskolski, Robert Kolodziejczyk
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 67(Pt 12)
Human fructose-1,6-bisphosphatase is an allosteric enzyme that is regulated by different ligands. There are only two known isozymes in human tissues: the liver isozyme (the key enzyme of gluconeogenesis), which is regulated by fructose 2,6-bisphospha
Autor:
Elżbieta Jankowska, Mariusz Jaskolski, Aneta Szymańska, Robert Kolodziejczyk, Marta Orlikowska
Publikováno v:
Journal of structural biology. 173(2)
Cystatins are natural inhibitors of cysteine proteases, enzymes that are widely distributed in animals, plants, and microorganisms. Human cystatin C (hCC) has been also recognized as an aggregating protein directly involved in the formation of pathol