Zobrazeno 1 - 10
of 331
pro vyhledávání: '"Robert, Klopfleisch"'
Autor:
Jonathan Ganz, Christian Marzahl, Jonas Ammeling, Emely Rosbach, Barbara Richter, Chloé Puget, Daniela Denk, Elena A. Demeter, Flaviu A. Tăbăran, Gabriel Wasinger, Karoline Lipnik, Marco Tecilla, Matthew J. Valentine, Michael J. Dark, Niklas Abele, Pompei Bolfa, Ramona Erber, Robert Klopfleisch, Sophie Merz, Taryn A. Donovan, Samir Jabari, Christof A. Bertram, Katharina Breininger, Marc Aubreville
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The count of mitotic figures (MFs) observed in hematoxylin and eosin (H&E)-stained slides is an important prognostic marker, as it is a measure for tumor cell proliferation. However, the identification of MFs has a known low inter-rater agre
Externí odkaz:
https://doaj.org/article/61a701a195d0421b9593f44c12f1b462
Autor:
Angelina Kraski, Paweł Migdał, Robert Klopfleisch, Clara Räckel, Jutta Sharbati, Markus M. Heimesaat, Thomas Alter, Carlos Hanisch, Greta Gölz, Ralf Einspanier, Soroush Sharbati
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background 3D cell culture models have recently garnered increasing attention for replicating organ microarchitecture and eliciting in vivo-like responses, holding significant promise across various biological disciplines. Broadly, 3D cell c
Externí odkaz:
https://doaj.org/article/c3b6302cf7f74b3dbcfc7457b80508e4
Autor:
Ankur Midha, Larissa Oser, Josephine Schlosser-Brandenburg, Alexandra Laubschat, Robert M. Mugo, Zaneta D. Musimbi, Philipp Höfler, Arkadi Kundik, Rima Hayani, Joshua Adjah, Saskia Groenhagen, Malte Tieke, Luis E. Elizalde-Velázquez, Anja A. Kühl, Robert Klopfleisch, Karsten Tedin, Sebastian Rausch, Susanne Hartmann
Publikováno v:
mSphere, Vol 9, Iss 9 (2024)
ABSTRACT Ascaris is one of the most widespread helminth infections, leading to chronic morbidity in humans and considerable economic losses in pig farming. In addition, pigs are an important reservoir for the zoonotic salmonellosis, where pigs can se
Externí odkaz:
https://doaj.org/article/98244c79ce29447698b26323f2819a17
Autor:
Marc Aubreville, Frauke Wilm, Nikolas Stathonikos, Katharina Breininger, Taryn A. Donovan, Samir Jabari, Mitko Veta, Jonathan Ganz, Jonas Ammeling, Paul J. van Diest, Robert Klopfleisch, Christof A. Bertram
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/79e04115ad314378bf65aa84a519e65d
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-14 (2024)
Abstract Background Itch sensitization has been reported in patients with chronic allergic skin diseases and observed in a mouse model of allergic contact dermatitis (ACD). There is evidence suggesting that neuroimmune interactions may contribute to
Externí odkaz:
https://doaj.org/article/2c4ba4d7707c4b8587ee2662af80a0f9
Autor:
Annika Bartel, Heike Aupperle-Lellbach, Alexandra Kehl, Silvia Weidle, Leonore Aeschlimann, Robert Klopfleisch, Simone de Brot
Publikováno v:
Veterinary Sciences, Vol 11, Iss 11, p 584 (2024)
Alterations of the BRAF gene and the resulting changes in the BRAF protein are one example of molecular cancer profiling in humans and dogs. We tested 227 samples of canine carcinomas from different anatomical sites (anal sac (n = 23), intestine (n =
Externí odkaz:
https://doaj.org/article/dfc357bd42564118b182bab3f9e260bf
Autor:
Mohamed Albadry, Jonas Küttner, Jan Grzegorzewski, Olaf Dirsch, Eva Kindler, Robert Klopfleisch, Vaclav Liska, Vladimira Moulisova, Sandra Nickel, Richard Palek, Jachym Rosendorf, Sylvia Saalfeld, Utz Settmacher, Hans-Michael Tautenhahn, Matthias König, Uta Dahmen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
There is a lack of systematic research exploring cross-species variation in liver lobular geometry and zonation patterns of critical drug-metabolizing enzymes, a knowledge gap essential for translational studies. This study investigated the critical
Externí odkaz:
https://doaj.org/article/46affa48e26a429382b68c799c8fe292
Autor:
Larissa Oser, Ankur Midha, Josephine Schlosser-Brandenburg, Sebastian Rausch, Robert M. Mugo, Arkadi Kundik, Luis E. Elizalde-Velázquez, Joshua Adjah, Zaneta D. Musimbi, Robert Klopfleisch, Christina S. Helm, Georg von Samson-Himmelstjerna, Susanne Hartmann, Friederike Ebner
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Ascaris spp. undergo extensive migration within the body before establishing patent infections in the small intestinal tract of humans and pigs. However, whether larval migration is critical for inducing efficient type 2 responses remains poorly unde
Externí odkaz:
https://doaj.org/article/8008e6abf43b4c25a7d89954bd7bba19
Autor:
Andreas Haghofer, Andrea Fuchs-Baumgartinger, Karoline Lipnik, Robert Klopfleisch, Marc Aubreville, Josef Scharinger, Herbert Weissenböck, Stephan M. Winkler, Christof A. Bertram
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Histopathological examination of tissue samples is essential for identifying tumor malignancy and the diagnosis of different types of tumor. In the case of lymphoma classification, nuclear size of the neoplastic lymphocytes is one of the key
Externí odkaz:
https://doaj.org/article/6307d0700a554608b5a74edf2a518bfc
Autor:
Imaine Glahn, Andreas Haghofer, Taryn A. Donovan, Brigitte Degasperi, Alexander Bartel, Theresa Kreilmeier-Berger, Philip S. Hyndman, Hannah Janout, Charles-Antoine Assenmacher, Florian Bartenschlager, Pompei Bolfa, Michael J. Dark, Andrea Klang, Robert Klopfleisch, Sophie Merz, Barbara Richter, F. Yvonne Schulman, Jonathan Ganz, Josef Scharinger, Marc Aubreville, Stephan M. Winkler, Christof A. Bertram
Publikováno v:
Veterinary Sciences, Vol 11, Iss 6, p 278 (2024)
The integration of deep learning-based tools into diagnostic workflows is increasingly prevalent due to their efficiency and reproducibility in various settings. We investigated the utility of automated nuclear morphometry for assessing nuclear pleom
Externí odkaz:
https://doaj.org/article/d3b917419c5f4b049009eb5d807f0748