Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Robert, Kleiman"'
Autor:
Robert Kleiman, Borje Darpo, Randy Brown, Todd Rudo, Svetlana Chamoun, David E. Albert, Johan Martijn Bos, Michael J. Ackerman
Publikováno v:
Annals of Noninvasive Electrocardiology, Vol 26, Iss 6, Pp n/a-n/a (2021)
Abstract Background Interval duration measurements (IDMs) were compared between standard 12‐lead electrocardiograms (ECGs) and 6‐lead ECGs recorded with AliveCor's KardiaMobile 6L, a hand‐held mobile device designed for use by patients at home.
Externí odkaz:
https://doaj.org/article/3912ef6d96c34b4aad920774d1089bf8
Autor:
Fabrizio, Stocchi, Elizabeth L, Peckham, Maria Francesca, De Pandis, Ken, Sciarappa, Robert, Kleiman, Felix, Agbo, C Warren, Olanow, David, Blum, Bradford, Navia
Publikováno v:
Clinical Pharmacology in Drug Development. 11:1068-1077
A randomized thorough QT study was conducted to assess the effects of apomorphine sublingual film (SL-APO) on corrected QT interval (QTc) and other cardiac conduction parameters in patients with Parkinson's disease (PD) and "OFF" episodes. Patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb20264c7fe1801c394d853dce3db9c
https://doi.org/10.1002/cpdd.1147
https://doi.org/10.1002/cpdd.1147
Autor:
Conner D. Galloway, David E. Albert, Michael J. Ackerman, Patrick W. Johnson, Robert Kleiman, Paul A. Friedman, Rickey E. Carter, Levi W. Disrud, Peter A. Noseworthy, Jacqueline Baras Shreibati, Zachi I. Attia, Matthew Schram, J. Martijn Bos, John R. Giudicessi
Publikováno v:
Circulation. 143:1274-1286
Background: Heart rate–corrected QT interval (QTc) prolongation, whether secondary to drugs, genetics including congenital long QT syndrome, and/or systemic diseases including SARS-CoV-2–mediated coronavirus disease 2019 (COVID-19), can predispos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a52deac1746022a443e4e52a53946ee8
https://doi.org/10.1161/circulationaha.120.050231
https://doi.org/10.1161/circulationaha.120.050231
Autor:
Hartmut Goldschmidt, Christoph Heuck, Markus Munder, Edward N. Libby, Maria Teresa Petrucci, Mehmet Turgut, Michele Cavo, Tobias Neff, Ming Qi, Katja Weisel, Robert Kleiman, Mario Boccadoro, Fatih Demirkan, Steven Kuppens, Ihsan Karadogan, Ajai Chari, Pamela L. Clemens, Rajesh Bandekar, Ceri Bygrave, Matthew W Jenner, Niels W.C.J. van de Donk
Publikováno v:
Advances in Therapy
Introduction Daratumumab is a CD38-targeting monoclonal antibody that has demonstrated clinical benefit for multiple myeloma. Daratumumab inhibition of CD38, which is expressed on immune cell populations and cardiomyocytes, could potentially affect c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ce97228f47369191000ad6884b6823
https://doi.org/10.1007/s12325-020-01601-w
https://doi.org/10.1007/s12325-020-01601-w
Publikováno v:
British Journal of Clinical Pharmacology
Aims Remimazolam is a new, ultra‐short‐acting benzodiazepine developed for intravenous (IV) use during procedural sedation and in general anaesthesia. Two trials were conducted to characterize its effects on cardiac repolarization. Methods A thor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7707ef57d7bcb3b4173817479e0e05e1
http://europepmc.org/articles/PMC7373701
http://europepmc.org/articles/PMC7373701
Autor:
Robert H. Cox, Charles Antzelevitch, Peter R. Kowey, Hector Barajas-Martinez, Michael J. Fossler, Robert Kleiman, Mark A. Demitrack, Michael S. Kramer, Alexander Burashnikov
Publikováno v:
Heart Rhythm
Background Oliceridine is a biased ligand at the μ-opioid receptor recently approved for the treatment of acute pain. In a thorough QT study, corrected QT (QTc) prolongation displayed peaks at 2.5 and 60 minutes after a supratherapeutic dose. The me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78debeb099afff8e49effb3a16f33c43
https://europepmc.org/articles/PMC8629933/
https://europepmc.org/articles/PMC8629933/
Autor:
Randy Brown, Todd Rudo, Borje Darpo, Michael J. Ackerman, Robert Kleiman, Johan M Bos, Svetlana Chamoun, David E. Albert
Publikováno v:
Annals of Noninvasive Electrocardiology
Annals of Noninvasive Electrocardiology, Vol 26, Iss 6, Pp n/a-n/a (2021)
Annals of Noninvasive Electrocardiology, Vol 26, Iss 6, Pp n/a-n/a (2021)
Background Interval duration measurements (IDMs) were compared between standard 12‐lead electrocardiograms (ECGs) and 6‐lead ECGs recorded with AliveCor's KardiaMobile 6L, a hand‐held mobile device designed for use by patients at home. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40f3cb0899bd1b36f8761442ac52af3
http://europepmc.org/articles/PMC8588372
http://europepmc.org/articles/PMC8588372
Autor:
Robert Kleiman, Stefan Schwabe, Gregory D. Busse, Maurizio Fava, Toyin Adewole, Shamia L. Faison, Tesfaye Liranso, Azmi Nasser
Publikováno v:
The Journal of clinical psychiatry. 81(6)
Objective To assess the effects of a supratherapeutic dose of SPN-812, a drug currently under investigation as a treatment for attention-deficit/hyperactivity disorder, on cardiac repolarization (QTc) in healthy adults. Methods The study was conducte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e9659d6b781b6fd2df025b548253e2
https://pubmed.ncbi.nlm.nih.gov/33049804
https://pubmed.ncbi.nlm.nih.gov/33049804
Autor:
Salim F. Idriss, Theressa J. Wright, Victoria L. Vetter, Stuart Berger, Valarie Morrow, Tess Saarel, Martha Lopez-Anderson, Allen Kindman, Mitchell W. Krucoff, Kimberly G. Harmon, Silvana Molossi, Kaori Shinagawa, Robert Kleiman, Thomas G. Todaro, Colette Strnadova
Publikováno v:
American Heart Journal. 190:123-131
This White Paper, prepared by members of the Cardiac Safety Research Consortium, discusses important issues regarding sudden cardiac death in the young (SCDY), a problem that does not discriminate by gender, race, ethnicity, education, socioeconomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074f19e716a59f3706dc121e15338bca
https://doi.org/10.1016/j.ahj.2017.05.003
https://doi.org/10.1016/j.ahj.2017.05.003
Autor:
Richard Clark, Paul D. Ziegler, Norman Stockbridge, Fraz A. Ismat, Mintu P. Turakhia, Suneet Mittal, Preston Dunnmon, Robert Kleiman, Peter R. Kowey, James A. Reiffel, Jonathan P. Piccini, Philip T. Sager
Publikováno v:
American Heart Journal. 187:156-169
This white paper, prepared by members of the Cardiac Safety Research Consortium (CSRC), discusses important issues regarding scientific and clinical aspects of long-term electrocardiographic safety monitoring during clinical drug development. To prom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ec90178a5fa633dc08aaa06c1b8a67
https://doi.org/10.1016/j.ahj.2017.01.012
https://doi.org/10.1016/j.ahj.2017.01.012