Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Robert, Kleemann"'
Autor:
Emma Custers, Yonta G.R. van der Burgh, Debby Vreeken, Frank Schuren, Tim J. van den Broek, Lars Verschuren, Ivo de Blaauw, Mark Bouwens, Robert Kleemann, Amanda J. Kiliaan, Eric J. Hazebroek
Publikováno v:
Heliyon, Vol 10, Iss 21, Pp e39899- (2024)
Unexplainable gastrointestinal complaints occasionally occur after Roux-en-Y Gastric Bypass (RYGB) surgery. We therefor investigated the impact of microbiota composition and metabolites on gastrointestinal complaints after RYGB. In the BARICO study (
Externí odkaz:
https://doaj.org/article/5bd7642de73c42d6a864be3fa334d513
Autor:
Lars Verschuren, Anne Linde Mak, Arianne van Koppen, Serdar Özsezen, Sonia Difrancesco, Martien P. M. Caspers, Jessica Snabel, David van der Meer, Anne-Marieke van Dijk, Elias Badal Rashu, Puria Nabilou, Mikkel Parsberg Werge, Koen van Son, Robert Kleemann, Amanda J. Kiliaan, Eric J. Hazebroek, André Boonstra, Willem P. Brouwer, Michail Doukas, Saurabh Gupta, Cornelis Kluft, Max Nieuwdorp, Joanne Verheij, Lise Lotte Gluud, Adriaan G. Holleboom, Maarten E. Tushuizen, Roeland Hanemaaijer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Accurate non-invasive biomarkers to diagnose metabolic dysfunction-associated steatotic liver disease (MASLD)-related fibrosis are urgently needed. This study applies a translational approach to develop a blood-based biomarker panel for fibr
Externí odkaz:
https://doaj.org/article/6be533e026b74a099d1ef00fbf2fcead
Autor:
Koen Hogenelst, Serdar Özsezen, Robert Kleemann, Lars Verschuren, Ivo Stuldreher, Charelle Bottenheft, Jan van Erp, Anne-Marie Brouwer
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 38, Iss , Pp 100789- (2024)
With the purpose of identifying a sensitive, robust, and easy-to-measure set of biomarkers to assess stress reactivity, we here study a large set of relatively easy to obtain markers reflecting subjective, autonomic nervous system (ANS), endocrine, a
Externí odkaz:
https://doaj.org/article/82fc25d27bc748d0902cc8e4fd50b581
Autor:
Emma Custers, Debby Vreeken, Frank Schuren, Tim J. van den Broek, Lieke van Dongen, Bram Geenen, Ivo de Blaauw, Maximilian Wiesmann, Eric J. Hazebroek, Robert Kleemann, Amanda J. Kiliaan
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 918 (2024)
Obesity is a multifactorial disease associated with low-grade inflammation. The gut is thought to be involved in obesity-related inflammation, as it is continuously exposed to antigens from food, microbiota and metabolites. However, the exact underly
Externí odkaz:
https://doaj.org/article/e42061bb6b974da9ae2228dd9c61dbcd
Autor:
Jelle C. B. C. de Jong, Lars Verschuren, Martien P. M. Caspers, Marjanne D. van der Hoek, Feike R. van der Leij, Robert Kleemann, Anita M. van den Hoek, Arie G. Nieuwenhuizen, Jaap Keijer
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background Physical weakness is a key component of frailty, and is highly prevalent in older adults. While females have a higher prevalence and earlier onset, sex differences in the development of frailty-related physical weakness are hardly
Externí odkaz:
https://doaj.org/article/8da9ab685829430a8ea35e5ca7a93789
Autor:
Charelle Bottenheft, Koen Hogenelst, Ivo Stuldreher, Robert Kleemann, Eric Groen, Jan van Erp, Anne-Marie Brouwer
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 34, Iss , Pp 100706- (2023)
Background: Sleep deprivation (SD) and acute social stress are common, often unavoidable, and frequently co-occurring stressors in high-risk professions. Both stressors are known to acutely induce inflammatory responses and an increasing body of lite
Externí odkaz:
https://doaj.org/article/c4c1c3dd2e494c1da75bf7cf06106296
Autor:
Florine Seidel, Kees Fluiter, Robert Kleemann, Nicole Worms, Anita van Nieuwkoop, Martien P. M. Caspers, Nikolaos Grigoriadis, Amanda J. Kiliaan, Frank Baas, Iliana Michailidou, Martine C. Morrison
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/2b51e3ec1f034710b793571b675ff6cc
Autor:
Florine Seidel, Kees Fluiter, Robert Kleemann, Nicole Worms, Anita van Nieuwkoop, Martien P. M. Caspers, Nikolaos Grigoriadis, Amanda J. Kiliaan, Frank Baas, Iliana Michailidou, Martine C. Morrison
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
IntroductionObesity has been linked to vascular dysfunction, cognitive impairment and neurodegenerative diseases. However, experimental models that recapitulate brain pathology in relation to obesity and vascular dysfunction are still lacking.Methods
Externí odkaz:
https://doaj.org/article/ce1aa71d47d747e49411fa68f117f960
Autor:
Eveline Gart, Wim van Duyvenvoorde, Jessica M. Snabel, Christa de Ruiter, Joline Attema, Martien P.M. Caspers, Serene Lek, Bertie Joan van Heuven, Arjen G.C.L. Speksnijder, Martin Giera, Aswin Menke, Kanita Salic, Kendra K. Bence, Gregory J. Tesz, Jaap Keijer, Robert Kleemann, Martine C. Morrison
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e13985- (2023)
Background: NAFLD progression, from steatosis to inflammation and fibrosis, results from an interplay of intra- and extrahepatic mechanisms. Disease drivers likely include signals from white adipose tissue (WAT) and gut. However, the temporal dynamic
Externí odkaz:
https://doaj.org/article/80936c4a408e43e2adff608faadaaab7
Autor:
Marcia Spoelder, Yami Bright, Martine C. Morrison, Veerle van Kempen, Lilian de Groodt, Malvina Begalli, Nikita Schuijt, Eva Kruiger, Ronald Bulthuis, Gabriele Gross, Robert Kleemann, Janna A. van Diepen, Judith R. Homberg
Publikováno v:
Cells, Vol 12, Iss 20, p 2463 (2023)
Increased insulin levels may support the development of neural circuits involved in cognition, while chronic mild inflammation may also result in cognitive impairment. This study aimed to gain more insight into whether cognition is already impacted d
Externí odkaz:
https://doaj.org/article/5f7c28dc8ba0460b98f31c8e6763f2de