Výsledky vyhledávání - "Robert, Kalak"

Data from Vitamin D Deficiency Promotes Human Breast Cancer Growth in a Murine Model of Bone Metastasis

Autor: Colin R. Dunstan, Markus J. Seibel, Arthur D. Conigrave, Yu Zheng, Robert Kalak, Hong Zhou, Li Laine Ooi

Vitamin D exerts antiproliferative, prodifferentiation, and proapoptotic effects on nonclassic target tissues such as breast. Blood levels of 25-hydroxyvitamin D [25(OH)D], the most sensitive indicator of vitamin D status, are inversely correlated wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc9cbc2b72ea514c83161ff20230210d
https://doi.org/10.1158/0008-5472.c.6500712

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Osteoblast-targeted disruption of glucocorticoid signalling does not delay intramembranous bone healing

Autor: Janine Street, Colin R. Dunstan, Hong Zhou, Frank Buttgereit, Markus J. Seibel, Gang Li, Robert Kalak, Agnes J. Weber

Publikováno v: Steroids. 75:282-286

Objective Glucocorticoids at pharmacological doses have been shown to interfere with fracture repair. The role of endogenous glucocorticoids in fracture healing is not well understood. We examined whether endogenous glucocorticoids affect bone healin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16de47d54a4b123494fcaef76042989f
https://doi.org/10.1016/j.steroids.2010.01.005

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Transgenic disruption of glucocorticoid signaling in mature osteoblasts and osteocytes attenuates K/BxN mouse serum-induced arthritis in vivo

Autor: Colin R. Dunstan, Markus J. Seibel, Frank Buttgereit, Dörte Huscher, Ranier H. Straub, Cornelia M. Spies, Robert Kalak, Hong Zhou, James R.K. Modzelewski, Timo Gaber

Publikováno v: Arthritis & Rheumatism. 60:1998-2007

Objective Endogenous glucocorticoids (GCs) modulate numerous biologic systems involved in the initiation and maintenance of arthritis. Bone cells play a critical role in the progression of arthritis, and some of the effects of GCs on inflammation may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b844fa31895e9d0e65cc3be3518130b0
https://doi.org/10.1002/art.24619

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Glucocorticoid-dependent Wnt signaling by mature osteoblasts is a key regulator of cranial skeletal development in mice

Autor: Hong Zhou, Colette Fong-Yee, Colin R. Dunstan, Markus J. Seibel, Robert Kalak, Wendy Mak, Janine Street, Yu Zheng

Publikováno v: Development. 136:427-436

Glucocorticoids are important regulators of bone cell differentiation and mesenchymal lineage commitment. Using a cell-specific approach of osteoblast-targeted transgenic disruption of intracellular glucocorticoid signaling, we discovered a novel mol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118fefca57b116ff1e6cece3d4522e45
https://doi.org/10.1242/dev.027706

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Is G→T substitution in the sequence of CAG repeats within the androgen receptor gene associated with aggressive behaviour in the red foxVulpes vulpes?

Autor: Dariusz Brzeziński, Joanna Lehmann, Marlena Szalata, Sławomir Nowicki, Wojciech Juzwa, Piotr Gronek, Wojciech Lassociński, Ryszard Słomski, Robert Kalak, Piotr Przysiecki

Publikováno v: Acta Theriologica. 53:17-25

Studies were carried out on one of the largest European red foxVulpes vulpes (Linnaeus, 1758) farms in Śniaty and Batorowka (Poland). A test created by Nowicki and Przysiecki (NP) was used to describe behaviour of the animals. The results of the NP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5cd48a6ca2b5c072fff0d2d6ad4382e4
https://doi.org/10.1007/bf03194275

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Association analysis of the polymorphisms of the VDR gene with bone mineral density and the occurrence of fractures

Autor: Michalina Marcinkowska, Liliana Celczyńska-Bajew, Ryszard Słomski, Anna Wawrzyniak, Robert Kalak, Wanda Horst-Sikorska

Publikováno v: Journal of Bone and Mineral Metabolism. 25:310-319

Associations of the FokI, BsmI, ApaI, and TaqI polymorphisms of the vitamin D receptor (VDR) gene with the bone mineral density (BMD) of the lumbar part of the spinal column (BMD LS) and the neck of the femur (BMD FN), and with the occurrence of frac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e566f79f16c02de2e0ae665a363abf
https://doi.org/10.1007/s00774-007-0769-5

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Molecular Diagnostics of Genetic Diseases: Experience from Studies of DMD, APC, TSC1, and OPG Genes. Part 1

Autor: Jolanta Jura, Tomasz Banasiewicz, Andrzej Pławski, Jadwiga Sowinska, Jaroslaw Wronka, Ryszard Słomski, Robert Kalak, Dobrawa Napierała

Publikováno v: Journal of Clinical Biochemistry and Nutrition. 28:113-127

Over the past decade geneticists have searched for rapid and efficient means of identification of genetic diseases. Nucleic acid techniques, such as restriction fragment length polymorphisms, polymerase chain reaction, and sequence analysis of amplif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::663cb05dc6b683e2c94f6f82a6569d94
https://doi.org/10.3164/jcbn.28.113

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Molecular Diagnostics of Genetic Diseases: Experience from Studies of DMD, APC, TSC1, and OPG Genes. Part 2

Autor: Ryszard Słomski, Robert Kalak, Jolanta Jura, Wanda Horst-Sikorska, David J. Kwiatkowski

Publikováno v: Journal of Clinical Biochemistry and Nutrition. 28:129-141

Tuberous sclerosis (TSC) is an autosomal dominant disease with variable penetrance, characterized by alterations in various organs including brain, heart, and kidneys. In about 2/3 of patients a family history of TSC is not observed. TSC is caused by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96910f2cb3605ada26964cdfe6ef36dd
https://doi.org/10.3164/jcbn.28.129

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