Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Robert, Bucki"'
Autor:
Maciej Karasiński, Urszula Wnorowska, Tamara Daniluk, Piotr Deptuła, Milena Łuckiewicz, Paulina Paprocka, Bonita Durnaś, Karol Skłodowski, Beata Sawczuk, Paul B. Savage, Ewelina Piktel, Robert Bucki
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7036 (2024)
A growing body of experimental data indicates that ceragenins (CSAs), which mimic the physicochemical properties of the host’s cationic antimicrobial peptide, hold promise for the development of a new group of broad-spectrum antimicrobials. Here, u
Externí odkaz:
https://doaj.org/article/6a4eaf6add9b4f8ab841ca3db9b17b00
Autor:
Tomasz Wollny, Łukasz Suprewicz, Jolanta Smok-Kalwat, Grażyna Antczak, Ewelina Piktel, Stanisław Góźdź, Bonita Durnaś, Robert Bucki
Publikováno v:
Studia Medyczne, Vol 39, Iss 2, Pp 103-113 (2023)
Externí odkaz:
https://doaj.org/article/f1a780adb0d743b685a608ae9de2ad35
Autor:
Marcin Zając, Joanna Kotyńska, Grzegorz Zambrowski, Joanna Breczko, Piotr Deptuła, Mateusz Cieśluk, Monika Zambrzycka, Izabela Święcicka, Robert Bucki, Monika Naumowicz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Polymer molecules, the main components of plastics, are an emerging pollutants in various environmental compartments (water, air, soil) that may induce several ecotoxicological effects on live organisms. Therefore, understanding how plastic
Externí odkaz:
https://doaj.org/article/14fa56e99fb548f392d22a0df2ed364a
Autor:
Urszula Wnorowska, Dawid Łysik, Ewelina Piktel, Magdalena Zakrzewska, Sławomir Okła, Agata Lesiak, Jakub Spałek, Joanna Mystkowska, Paul B Savage, Paul Janmey, Krzysztof Fiedoruk, Robert Bucki
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0298112 (2024)
BackgroundMicrobial biofilms, as a hallmark of cystic fibrosis (CF) lung disease and other chronic infections, remain a desirable target for antimicrobial therapy. These biopolymer-based viscoelastic structures protect pathogenic organisms from immun
Externí odkaz:
https://doaj.org/article/99e5103b6807477fb6b1e5499e7fde33
Autor:
Ewelina Piktel, Urszula Wnorowska, Joanna Gorbacz-Konończuk, Jakub Sienkiewicz, Katarzyna Głuszek, Sławomir Okła, Robert Bucki
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Antimicrobial peptides (AMPs), commonly referred to as host defense peptides, are found in a wide range of organisms, including bacteria, plants, and both vertebrate and invertebrate animals. They function as an initial defense mechanism against path
Externí odkaz:
https://doaj.org/article/4553cf5accec4916a0a8ade13760eced
Autor:
Karol Skłodowski, Łukasz Suprewicz, Sylwia Joanna Chmielewska-Deptuła, Szczepan Kaliniak, Sławomir Okła, Magdalena Zakrzewska, Łukasz Minarowski, Robert Mróz, Tamara Daniluk, Paul B. Savage, Krzysztof Fiedoruk, Robert Bucki
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The purpose of the work was to investigate the impact of sodium chloride (NaCl) on the antimicrobial efficacy of ceragenins (CSAs) and antimicrobial peptides (AMPs) against bacterial and fungal pathogens associated with cystic fibrosis (CF) lung infe
Externí odkaz:
https://doaj.org/article/d9f8cdf72ad0416e819ef345cc844e6e
Autor:
Michał Czarnowski, Monika Słowińska, Mariusz Sawieljew, Urszula Wnorowska, Tamara Daniluk, Grzegorz Król, Maciej Karasiński, Sławomir Okła, Paul B. Savage, Ewelina Piktel, Robert Bucki
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 204 (2024)
Ensuring proper dental hygiene is of paramount importance for individuals’ general well-being, particularly for patients receiving medical care. There is a prevailing utilization of conventional oral hygiene items, including toothbrushes and mouthw
Externí odkaz:
https://doaj.org/article/5a1ac1ba9ad74aae8beae988a20374d8
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Ceragenins, including CSA-13, are cationic antimicrobials that target the bacterial cell envelope differently than colistin. However, the molecular basis of their action is not fully understood. Here, we examined the genomic and transcriptom
Externí odkaz:
https://doaj.org/article/6845d3223675441a984680e7766a8726
Autor:
Łukasz Suprewicz, Kiet A. Tran, Ewelina Piktel, Krzysztof Fiedoruk, Paul A. Janmey, Peter A. Galie, Robert Bucki
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-16 (2022)
Abstract Background Plasma gelsolin (pGSN) is an important part of the blood actin buffer that prevents negative consequences of possible F-actin deposition in the microcirculation and has various functions during host immune response. Recent reports
Externí odkaz:
https://doaj.org/article/443198935aff4306b3fd9dda4e87aa5c
Autor:
Urszula Wnorowska, Ewelina Piktel, Piotr Deptuła, Tomasz Wollny, Grzegorz Król, Katarzyna Głuszek, Bonita Durnaś, Katarzyna Pogoda, Paul B. Savage, Robert Bucki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Ceragenins (CSAs) are synthetic, lipid-based molecules that display activities of natural antimicrobial peptides. Previous studies demonstrated their high in vitro activity against pathogens causing urinary tract infections (UTIs), but their
Externí odkaz:
https://doaj.org/article/e6ffa29d7dee4afd9ff39797f06ac20b