Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Robert, Ahrends"'
Autor:
Susanne Heimerl, Marcus Höring, Dominik Kopczynski, Alexander Sigruener, Christina Hart, Ralph Burkhardt, Anne Black, Robert Ahrends, Gerhard Liebisch
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Lipids play a central role in platelet physiology. Changes in the lipidome have already been described for basal and activated platelets. However, quantitative lipidomic data of platelet activation, including the released complex lipids, are
Externí odkaz:
https://doaj.org/article/3203d4903e8e4865ae3716ca28701982
Autor:
Qingqing Wang, Miriam Hoene, Chunxiu Hu, Louise Fritsche, Robert Ahrends, Gerhard Liebisch, Kim Ekroos, Andreas Fritsche, Andreas L. Birkenfeld, Xinyu Liu, Xinjie Zhao, Qi Li, Benzhe Su, Andreas Peter, Guowang Xu, Rainer Lehmann
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 6, Pp 100378- (2023)
Reliability, robustness, and interlaboratory comparability of quantitative measurements is critical for clinical lipidomics studies. Lipids’ different ex vivo stability in blood bears the risk of misinterpretation of data. Clear recommendations for
Externí odkaz:
https://doaj.org/article/a42ab799f397406da6b28c7fe9b90fe6
Autor:
Alessandro Dario Confettura, Eleonora Cuboni, Mohamed Rafeet Ammar, Shaobo Jia, Guilherme M. Gomes, PingAn Yuanxiang, Rajeev Raman, Tingting Li, Katarzyna M. Grochowska, Robert Ahrends, Anna Karpova, Alexander Dityatev, Michael R. Kreutz
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-18 (2022)
Abstract Background The metabolic syndrome is a consequence of modern lifestyle that causes synaptic insulin resistance and cognitive deficits and that in interaction with a high amyloid load is an important risk factor for Alzheimer's disease. It ha
Externí odkaz:
https://doaj.org/article/8050b454059242799298a70205d8078a
Autor:
Denise Wolrab, Robert Jirásko, Eva Cífková, Marcus Höring, Ding Mei, Michaela Chocholoušková, Ondřej Peterka, Jakub Idkowiak, Tereza Hrnčiarová, Ladislav Kuchař, Robert Ahrends, Radana Brumarová, David Friedecký, Gabriel Vivo-Truyols, Pavel Škrha, Jan Škrha, Radek Kučera, Bohuslav Melichar, Gerhard Liebisch, Ralph Burkhardt, Markus R. Wenk, Amaury Cazenave-Gassiot, Petr Karásek, Ivo Novotný, Kristína Greplová, Roman Hrstka, Michal Holčapek
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Patients with pancreatic cancer have a poor prognosis, more research is required to identify the disease at an earlier stage. Here, the authors use lipid profiles of blood samples and show that they can distinguish patients with pancreatic cancer fro
Externí odkaz:
https://doaj.org/article/fab714422846417696ab9c2c63c8d5e0
Autor:
Harald C. Köfeler, Thomas O. Eichmann, Robert Ahrends, John A. Bowden, Niklas Danne-Rasche, Edward A. Dennis, Maria Fedorova, William J. Griffiths, Xianlin Han, Jürgen Hartler, Michal Holčapek, Robert Jirásko, Jeremy P. Koelmel, Christer S. Ejsing, Gerhard Liebisch, Zhixu Ni, Valerie B. O’Donnell, Oswald Quehenberger, Dominik Schwudke, Andrej Shevchenko, Michael J. O. Wakelam, Markus R. Wenk, Denise Wolrab, Kim Ekroos
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-4 (2021)
Externí odkaz:
https://doaj.org/article/83316378728a498088000222c0fb33af
Autor:
Robert A. Ariëns, Beverley J. Hunt, Ejaife O. Agbani, Josefin Ahnström, Robert Ahrends, Raza Alikhan, Alice Assinger, Zsuzsa Bagoly, Alessandra Balduini, Elena Barbon, Christopher D. Barrett, Paul Batty, Jorge David Aivazoglou Carneiro, Wee Shian Chan, Moniek deMaat, Kerstin deWit, Cécile Denis, Martin H. Ellis, Renee Eslick, Hongxia Fu, Catherine P. M. Hayward, Benoit Ho‐Tin‐Noé, Frederikus A. Klok, Riten Kumar, Karin Leiderman, Rustem I. Litvinov, Nigel Mackman, Zoe McQuilten, Matthew D. Neal, William A. E. Parker, Roger J. S. Preston, Julie Rayes, Alireza R. Rezaie, Lara N. Roberts, Bianca Rocca, Susan Shapiro, Deborah M. Siegal, Lirlândia P. Sousa, Katsue Suzuki‐Inoue, Tahira Zafar, Jiaxi Zhou
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 5, Pp n/a-n/a (2022)
Abstract The ISTH London 2022 Congress is the first held (mostly) face‐to‐face again since the COVID‐19 pandemic took the world by surprise in 2020. For 2 years we met virtually, but this year’s in‐person format will allow the ever‐so‐i
Externí odkaz:
https://doaj.org/article/f79ff8eebaef425b98250762e3be6774
Autor:
Johanna P. van Geffen, Frauke Swieringa, Kim van Kuijk, Bibian M. E. Tullemans, Fiorella A. Solari, Bing Peng, Kenneth J. Clemetson, Richard W. Farndale, Ludwig J. Dubois, Albert Sickmann, René P. Zahedi, Robert Ahrends, Erik A. L. Biessen, Judith C. Sluimer, Johan W. M. Heemskerk, Marijke J. E. Kuijpers
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Hyperlipidemia is a well-established risk factor for cardiovascular diseases. Millions of people worldwide display mildly elevated levels of plasma lipids and cholesterol linked to diet and life-style. While the prothrombotic risk of severe
Externí odkaz:
https://doaj.org/article/1989a910cf91487588230cb6fcebb5c1
Autor:
Stefan Reich, Chi D. L. Nguyen, Canan Has, Sascha Steltgens, Himanshu Soni, Cristina Coman, Moritz Freyberg, Anna Bichler, Nicole Seifert, Dominik Conrad, Christiane B. Knobbe-Thomsen, Björn Tews, Grischa Toedt, Robert Ahrends, Jan Medenbach
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The unfolded protein response (UPR) is a stress response pathway implicated in numerous diseases and chemotherapy resistance. Here, the authors define the UPR regulon with a multi-omics strategy, uncovering changes to mitochondrial one-carbon metabol
Externí odkaz:
https://doaj.org/article/79d8f5e4871145f68820d3fe6d215985
Autor:
Bing Peng, Dominik Kopczynski, Brian S. Pratt, Christer S. Ejsing, Bo Burla, Martin Hermansson, Peter Imre Benke, Sock Hwee Tan, Mark Y. Chan, Federico Torta, Dominik Schwudke, Sven W. Meckelmann, Cristina Coman, Oliver J. Schmitz, Brendan MacLean, Mailin-Christin Manke, Oliver Borst, Markus R. Wenk, Nils Hoffmann, Robert Ahrends
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Targeted mass spectrometry enables reproducible and accurate lipid quantification but dedicated software tools to develop targeted lipidomics assays are lacking. Here, the authors develop a targeted lipidomics workbench and lipid knowledgebase for th
Externí odkaz:
https://doaj.org/article/cf125a979bd74b198ac9797a20846f29
Autor:
Matthew J. Jennings, Denisa Hathazi, Chi D. L. Nguyen, Benjamin Munro, Ute Münchberg, Robert Ahrends, Annette Schenck, Ilse Eidhof, Erik Freier, Matthis Synofzik, Rita Horvath, Andreas Roos
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Recessive mutations in DNAJC3, an endoplasmic reticulum (ER)-resident BiP co-chaperone, have been identified in patients with multisystemic neurodegeneration and diabetes mellitus. To further unravel these pathomechanisms, we employed a non-biased pr
Externí odkaz:
https://doaj.org/article/d37f7a362bf742d5823db37a44e3b415