Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Robbert Zalm"'
Autor:
Mariana R. Matos, Esther Visser, Ioannis Kramvis, Rolinka J. van der Loo, Titia Gebuis, Robbert Zalm, Priyanka Rao-Ruiz, Huibert D. Mansvelder, August B. Smit, Michel C. van den Oever
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Little is known about mechanisms that regulate the involvement of cortical engram cells in remote memory. Here, authors demonstrate that memory consolidation by mPFC engram cells requires CREB-mediated transcription, with the functionality of this ne
Externí odkaz:
https://doaj.org/article/2dcc06a021f6409fbd0f338e392bb063
Autor:
Juliane Lauks, Patricia Klemmer, Fatima Farzana, Ramesh Karupothula, Robbert Zalm, Nancy E Cooke, Ka Wan Li, August B Smit, Ruud Toonen, Matthijs Verhage
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39420 (2012)
Neurobeachin (Nbea) is a multidomain scaffold protein abundant in the brain, where it is highly expressed during development. Nbea-null mice have severe defects in neuromuscular synaptic transmission resulting in lethal paralysis of the newborns. Rec
Externí odkaz:
https://doaj.org/article/0ad1219ee7ac4e6a8531c41d5498cbea
Autor:
Rolinka J. van der Loo, Mariana R. Matos, Priyanka Rao-Ruiz, Esther Visser, Titia Gebuis, Michel C. van den Oever, August B. Smit, Ioannis Kramvis, Huibert D. Mansvelder, Robbert Zalm
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Matos, M R, Visser, E, Kramvis, I, van der Loo, R J, Gebuis, T, Zalm, R, Rao-Ruiz, P, Mansvelder, H D, Smit, A B & van den Oever, M C 2019, ' Memory strength gates the involvement of a CREB-dependent cortical fear engram in remote memory ', Nature Communications, vol. 10, 2315, pp. 1-11 . https://doi.org/10.1038/s41467-019-10266-1
Nature Communications, 10:2315, 1-11. Nature Publishing Group
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Matos, M R, Visser, E, Kramvis, I, van der Loo, R J, Gebuis, T, Zalm, R, Rao-Ruiz, P, Mansvelder, H D, Smit, A B & van den Oever, M C 2019, ' Memory strength gates the involvement of a CREB-dependent cortical fear engram in remote memory ', Nature Communications, vol. 10, 2315, pp. 1-11 . https://doi.org/10.1038/s41467-019-10266-1
Nature Communications, 10:2315, 1-11. Nature Publishing Group
Encoding and retrieval of contextual memories is initially mediated by sparsely activated neurons, so-called engram cells, in the hippocampus. Subsequent memory persistence is thought to depend on network-wide changes involving progressive contributi
Autor:
August B. Smit, Ka Wan Li, Fatima Farzana, Robbert Zalm, Ruud F. Toonen, Matthijs Verhage, Ning Chen, Seth G. N. Grant
Publikováno v:
Molecular Neurobiology, 53(4), 2112-2123. Humana Press
Farzana, F, Zalm, R, Chen, N, Li, K W, Grant, S G N, Smit, A B, Toonen, R F & Verhage, M 2016, ' Neurobeachin Regulates Glutamate-and GABA-Receptor Targeting to Synapses via Distinct Pathways ', Molecular Neurobiology, vol. 53, no. 4, pp. 2112-2123 . https://doi.org/10.1007/s12035-015-9164-8
Farzana, F, Zalm, R, Chen, N, Li, K W, Grant, S G, Smit, A B, Toonen, R F G & Verhage, M 2016, ' Neurobeachin Regulates Glutamate-and GABA-Receptor Targeting to Synapses via Distinct Pathways. ', Molecular Neurobiology, vol. 53, no. 4, pp. 2112-2123 . https://doi.org/10.1007/s12035-015-9164-8
Molecular Neurobiology
Farzana, F, Zalm, R, Chen, N, Li, K W, Grant, S G N, Smit, A B, Toonen, R F & Verhage, M 2016, ' Neurobeachin Regulates Glutamate-and GABA-Receptor Targeting to Synapses via Distinct Pathways ', Molecular Neurobiology, vol. 53, no. 4, pp. 2112-2123 . https://doi.org/10.1007/s12035-015-9164-8
Farzana, F, Zalm, R, Chen, N, Li, K W, Grant, S G, Smit, A B, Toonen, R F G & Verhage, M 2016, ' Neurobeachin Regulates Glutamate-and GABA-Receptor Targeting to Synapses via Distinct Pathways. ', Molecular Neurobiology, vol. 53, no. 4, pp. 2112-2123 . https://doi.org/10.1007/s12035-015-9164-8
Molecular Neurobiology
Neurotransmission and synaptic strength depend on expression of post-synaptic receptors on the cell surface. Post-translational modification of receptors, trafficking to the synapse through the secretory pathway, and subsequent insertion into the syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a7b44daad0bc20e890fcefa12991eb
https://research.vumc.nl/en/publications/6880a639-a3b1-40b3-806e-557d777e93ec
https://research.vumc.nl/en/publications/6880a639-a3b1-40b3-806e-557d777e93ec
Publikováno v:
Journal of Neurochemistry. 93:1393-1400
Munc18–1, a member of the Sec1/Munc18 (SM) protein family, is essential for synaptic vesicle exocytosis. Munc18–1 binds tightly to the SNARE protein syntaxin 1, but the physiological significance and functional role of this interaction remain unc
Publikováno v:
Journal of neurochemistry. 93(6)
Munc18-1, a member of the Sec1/Munc18 (SM) protein family, is essential for synaptic vesicle exocytosis. Munc18-1 binds tightly to the SNARE protein syntaxin 1, but the physiological significance and functional role of this interaction remain unclear