Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Robbert Créton"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
IntroductionAnimals respond to various environmental cues. Animal behavior is complex, and behavior analysis can greatly help to understand brain function. Most of the available behavioral imaging setups are expensive, provide limited options for cus
Externí odkaz:
https://doaj.org/article/a839d6f5aec64425a24b1652ef402d7a
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116096- (2024)
Drug repurposing can accelerate drug development while reducing the cost and risk of toxicity typically associated with de novo drug design. Several disorders lacking pharmacological solutions and exhibiting poor results in clinical trials - such as
Externí odkaz:
https://doaj.org/article/f42096f654b043fab1198133efb03db0
Autor:
Thaís Del Rosario Hernández, Narendra R. Joshi, Sayali V. Gore, Jill A. Kreiling, Robbert Creton
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The analysis of mouse behavior is used in biomedical research to study brain function in health and disease. Well-established rapid assays allow for high-throughput analyses of behavior but have several drawbacks, including measurements of d
Externí odkaz:
https://doaj.org/article/65a1fa29d6114a2caf0c2c91106a157a
Autor:
Sayali V. Gore, Rohit Kakodkar, Thaís Del Rosario Hernández, Sara Tucker Edmister, Robbert Creton
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Brain function studies greatly depend on quantification and analysis of behavior. While behavior can be imaged efficiently, the quantification of specific aspects of behavior is labor-intensive and may introduce individual biases. Recent adv
Externí odkaz:
https://doaj.org/article/fb57bbc689ab4d35a930b7089632a2c9
Autor:
Sara Tucker Edmister, Thaís Del Rosario Hernández, Rahma Ibrahim, Cameron A. Brown, Sayali V. Gore, Rohit Kakodkar, Jill A. Kreiling, Robbert Creton
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Repurposing FDA-approved drugs is an efficient and cost-effective approach in the development of therapeutics for a broad range of diseases. However, prediction of function can be challenging, especially in the brain. We screened a small-mol
Externí odkaz:
https://doaj.org/article/3472d223bf7649b083724040210b41d4
Autor:
Robbert Créton, Lionel F. Jaffe
Publikováno v:
BioTechniques, Vol 31, Iss 5, Pp 1098-1105 (2001)
Chemiluminescence has become a standard tool in biomedical research. Chemiluminescent probes are used for immunoassays, nucleic acid identification, reporter gene assays, measuring enzyme activity, and the detection of ions and small molecules such a
Externí odkaz:
https://doaj.org/article/d51996e4740d4677ba0afb61637a27a0
Publikováno v:
Roux's archives of developmental biology : the official organ of the EDBO. 204(1)
All-trans retinoic acid is well known as a modulator of positional specification in vertebrate development. A similar mechanism may operate in molluscan development. Molluscan development is characterized by an invariant pattern of cell divisions, wh
Publikováno v:
Roux's archives of developmental biology : the official organ of the EDBO. 200(6)
InLymnaea stagnalis, mesoderm induction occurs at the 24-cell stage, when the apical tip of the macromere 3D establishes a close contact with a number of micromeres. Via its tip, the macromere 3D is supposed to receive an inductive signal from the mi
Publikováno v:
Roux's archives of developmental biology : the official organ of the EDBO. 200(3)
During the first four mitotic division cycles of Lymnaea stagnalis embryos, we have detected cell cycle-dependent changes in the pattern of transcellular ionic currents and membrane-bound Ca
Publikováno v:
Roux's archives of developmental biology : the official organ of the EDBO. 199(3)
During extrusion of the first polar body in eggs ofLymnaea stagnalis andBithynia tentaculata a localized Ca