Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Robabeh Kalhor"'
Autor:
Robabeh Kalhor, Paul R. Gilson, Kiaran Kirk, Alan F. Cowman, Adele M. Lehane, Anthony T. Papenfuss, Tania F. de Koning-Ward, Mark D. Hulett, Rasika Kumarasingha, Jennifer K. Thompson, Jessica K. Holien, Belinda M. Abbott, Madeline G Dans, Jocelyn Sietsma Penington, Xinxin Zhang, Hayley E Bullen, Melissa J. Buskes, Brendan S. Crabb, Tatiana P. Soares da Costa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
We developed a novel series of antimalarial compounds based on a 4-cyano-3-methylisoquinoline. Our lead compound MB14 achieved modest inhibition of the growth in vitro of the human malaria parasite, Plasmodium falciparum. To identify its biological t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da2db203f56119a2708aeaad5739853
https://doi.org/10.1038/s41598-019-46500-5
https://doi.org/10.1038/s41598-019-46500-5
Autor:
Leslie W. Deady, Nathan J. O'Brien, Elliott D. Cope, Brendan S. Crabb, Belinda M. Abbott, Chamodi K. Gardhi, Greta E. Weiss, Melissa J. Buskes, Rebecca M. Christoff, Robabeh Kalhor, Paul R. Gilson, Boris Prinz, Dene R. Littler, Benjamin J. Richards, Katherine L. Harvey
Publikováno v:
Organic & Biomolecular Chemistry. 14:4617-4639
Central to malaria pathogenesis is the invasion of human red blood cells by Plasmodium falciparum parasites. Following each cycle of intracellular development and replication, parasites activate a cellular program to egress from their current host ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc507a46e38bcf23e43e61926e9a482e
https://doi.org/10.1039/c5ob02517f
https://doi.org/10.1039/c5ob02517f