Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Rob van Dalen"'
Autor:
Rob van Dalen, Ahmed M. A. Elsherbini, Mareike Harms, Svenja Alber, Regine Stemmler, Andreas Peschel
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract Background Respiratory mucosal host defense relies on the production of secretory IgA (sIgA) antibodies, but we currently lack a fundamental understanding of how sIgA is induced by contact with microbes and how such immune responses may vary
Externí odkaz:
https://doaj.org/article/26f0067530e34ac89285dc85d3ed28e4
Autor:
Eike-Christian Wamhoff, Jessica Schulze, Lydia Bellmann, Mareike Rentzsch, Gunnar Bachem, Felix F. Fuchsberger, Juliane Rademacher, Martin Hermann, Barbara Del Frari, Rob van Dalen, David Hartmann, Nina M. van Sorge, Oliver Seitz, Patrizia Stoitzner, Christoph Rademacher
Publikováno v:
ACS Central Science, Vol 5, Iss 5, Pp 808-820 (2019)
Externí odkaz:
https://doaj.org/article/b243f0a6863149e4926bb2729fa8b4e5
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Antigen-presenting cells (APCs) are present throughout the human body—in tissues, at barrier sites and in the circulation. They are critical for processing external signals to instruct both local and systemic responses toward immune tolerance or im
Externí odkaz:
https://doaj.org/article/ae31bfee506845db96c9d0df6ae58f2f
Autor:
Rob van Dalen, Jacinto S. De La Cruz Diaz, Matevž Rumpret, Felix F. Fuchsberger, Nienke H. van Teijlingen, Jonas Hanske, Christoph Rademacher, Teunis B. H. Geijtenbeek, Jos A. G. van Strijp, Christopher Weidenmaier, Andreas Peschel, Daniel H. Kaplan, Nina M. van Sorge
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Staphylococcus aureus is a major cause of skin and soft tissue infections and aggravator of the inflammatory skin disease atopic dermatitis (AD [eczema]). Epicutaneous exposure to S. aureus induces Th17 responses through skin Langerhans cell
Externí odkaz:
https://doaj.org/article/5381197dcad241c8928ae7c4eb2becaf
Autor:
Rob van Dalen, Ahmed M. A. Elsherbini, Mareike Harms, Svenja Alber, Regine Stemmler, Andreas Peschel
The human nasal microbiome is critical for health and disease, since it is associated with the occurrence of respiratory disorders and hosting of opportunistic pathogens. The host therefore protects this vulnerable mucosal barrier from infection and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b112805096a26270452c032d5c7f05ae
https://doi.org/10.1101/2022.08.31.505993
https://doi.org/10.1101/2022.08.31.505993
Autor:
Sara Ali, Thomas Bruyning, Jeroen D. C. Codée, Nina M. van Sorge, Astrid Hendriks, Rob van Dalen, Herman S. Overkleeft, Dmitri V. Filippov, Nico J. Meeuwenoord, Gijs A. van der Marel
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany), 27(40), 10461-10469. Wiley-VCH Verlag
Chemistry-a European Journal, 27(40), 10461-10469. WILEY-V C H VERLAG GMBH
Chemistry-a European Journal
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry-a European Journal, 27(40), 10461-10469. WILEY-V C H VERLAG GMBH
Chemistry-a European Journal
Chemistry (Weinheim an Der Bergstrasse, Germany)
Wall teichoic acids (WTAs) are important components of the cell wall of the opportunistic Gram‐positive bacterium Staphylococcus aureus. WTAs are composed of repeating ribitol phosphate (RboP) residues that are decorated with d‐alanine and N‐ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9eb2a2349b9aecfcd39b5078b89626
https://hdl.handle.net/1887/3214360
https://hdl.handle.net/1887/3214360
Autor:
Felix F. Fuchsberger, Rob van Dalen, Nina M. van Sorge, Jos A. G. van Strijp, Christoph Rademacher
Publikováno v:
Journal of Innate Immunity. 12:191-200
Langerhans cells are key sentinel cells of the skin and mucosal lining. They sense microorganisms through their repertoire of pattern-recognition receptors to mount and direct appropriate immune responses. We recently demonstrated that human Langerha
Autor:
David Gerlach, Carla J. C. de Haas, Gijsbert A. van der Marel, Piet C. Aerts, Astrid Hendriks, Jeroen D. C. Codée, Andreas Peschel, Felix F. Fuchsberger, Rob van Dalen, Nina M. van Sorge, Jos A. G. van Strijp, Christoph Rademacher, Sara Ali
Publikováno v:
ACS Infectious Diseases
ACS Infectious Diseases, 7(3), 624-635. American Chemical Society
ACS Infectious Diseases, 7(3), 624-635
ACS Infectious Diseases, 7(3), 624-635. American Chemical Society
ACS Infectious Diseases, 7(3), 624-635
Staphylococcus aureus is the leading cause of skin and soft tissue infections. It remains incompletely understood how skin-resident immune cells respond to invading S. aureus and contribute to an effective immune response. Langerhans cells (LCs), the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2f0a45c67eaa6316d95464f8f74768
https://doi.org/10.1021/acsinfecdis.0c00822
https://doi.org/10.1021/acsinfecdis.0c00822
Publikováno v:
Trends in microbiology. 28(10)
Autor:
Jeffrey Downey, Leandro Silva da Costa, Armin Farahvash, Stephen E. Girardin, Aaron Trotman-Grant, Ryan G. Gaudet, Maziar Divangahi, Leticia A.M. Carneiro, Damien Arnoult, Farshad C. Azimi, Jeffrey E. Lee, Charles C. Y. Lau, Raphael Molinaro, Nichole K. Escalante, Dave Prescott, Scott D. Gray-Owen, Elise Sofie Hovingh, J J Chen, Ahmed Outlioua, Dana J. Philpott, Jessica Tsalikis, Rob van Dalen, Mena Abdel-Nour
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2019, 365 (6448), pp.eaaw4144. ⟨10.1126/science.aaw4144⟩
Science, American Association for the Advancement of Science, 2019, 365 (6448), pp.eaaw4144. ⟨10.1126/science.aaw4144⟩
Linking protein misfolding and innate immunity Multiple innate immune sensors undergo rapid assembly into large complexes known as signalosomes. This is an essential step during cellular responses to microbes and danger signals. How this process is r