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Autor:
Fred W. van Leeuwen, Rob W. H. Hermanussen, M. A. F. Sonnemans, D.A.P. Evans, Kum-Fai Chooi, Ewoud Moraal, David Murphy, David F. Fischer, Elly M. Hol, J. Peter H. Burbach
Publikováno v:
The FASEB Journal. 14:1595-1602
+1 Frame-shifted proteins such as amyloid precursor protein+1 and ubiquitin-B+1 have been identified in the neuropathological hallmarks of Alzheimer’s disease. These frameshifts are caused by dinucleotide deletions in GAGAG motifs of messenger RNA