Zobrazeno 1 - 10
of 104 318
pro vyhledávání: '"Rob P"'
Autor:
Tamara C. A. I. Verbeek, Kirsten S. Vrenken, Susan T. C. J. M. Arentsen-Peters, Patricia Garrido Castro, Marieke van de Ven, Olaf van Tellingen, Rob Pieters, Ronald W. Stam
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract KMT2A-rearranged acute lymphoblastic leukemia (ALL) is characterized by deregulation of the epigenome and shows susceptibility towards histone deacetylase (HDAC) inhibition. Most broad-spectrum HDAC inhibitors simultaneously target multiple
Externí odkaz:
https://doaj.org/article/e000296a1f8e439791267dfa6e9c542d
Autor:
Aimée S. R. Westerveld, Pien Roesthuis, Helena J. H. van der Pal, Dorine Bresters, Marc Bierings, Jacqueline Loonen, Andrica C. H. de Vries, Marloes Louwerens, Maria M. W. Koopman, Marry M. van den Heuvel-Eibrink, Margriet van der Heiden-van der Loo, Peter Hoogerbrugge, Geert O. Janssens, Ronald R. de Krijger, Cecile M. Ronckers, Rob Pieters, Leontien C. M. Kremer, Jop C. Teepen
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Acute lymphoblastic leukemia (ALL) survivors are at risk for developing subsequent neoplasms, but there is limited information on long-term risks and risk factors for both subsequent malignant neoplasms (SMNs) and subsequent non-malignant ne
Externí odkaz:
https://doaj.org/article/dd1578a6e4ab4a39aa7be9fb7ad260a1
Autor:
Rob Poole
Publikováno v:
BJPsych Bulletin, Vol 48, Pp 245-249 (2024)
This paper reflects on a special edition of the journal History of Psychiatry and a related symposium held at Somerville College, Oxford, exploring the innovations in mental healthcare in Oxfordshire led by Dr Bertram Mandelbrote between 1959 and 198
Externí odkaz:
https://doaj.org/article/36474b94c6af4eeb90d8d078ce1ea0d7
Publikováno v:
BJPsych Bulletin, Vol 48, Pp 221-225 (2024)
Aims and method Calls for the integration of spirituality into psychiatric practice have raised concerns about boundary violations. We sought to develop a method to capture psychiatrists’ attitudes to professional boundaries and spirituality, explo
Externí odkaz:
https://doaj.org/article/5617689c0b0a4169b15d073d9a4d73de
Publikováno v:
EJC Paediatric Oncology, Vol 4, Iss , Pp 100204- (2024)
KMT2A-rearranged acute lymphoblastic leukaemia (ALL) represents a high risk subtype of childhood ALL. Historical treatment strategies have comprised of intensification with conventional chemotherapy. However, outcomes have remained consistently poor
Externí odkaz:
https://doaj.org/article/ed77b18b8df94a55ae1556f991d6f64c
Autor:
Dongrui Li, Shenghua Zong, Yaobing Yao, Peter C. Molenaar, Jan G. M. C. Damoiseaux, Hui Li, Rob P. W. Rouhl, Pilar Martinez-Martinez
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAnti-GABABR encephalitis is a rare disease reported to be often associated with tumors. The current study aims to summarize the clinical characteristics, imaging features, treatments, outcomes and explore the potential prognosis risk fact
Externí odkaz:
https://doaj.org/article/b34a6d8fb4414c7abfe07ed2a84501a6
Publikováno v:
Algorithms for Molecular Biology, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Purpose String indexes such as the suffix array (sa) and the closely related longest common prefix (lcp) array are fundamental objects in bioinformatics and have a wide variety of applications. Despite their importance in practice, few scala
Externí odkaz:
https://doaj.org/article/79aae57e7f2345199d9e1c1cff770744
Autor:
Karen Dahri, Yiu-Ching Jennifer Wong, Peter Loewen, Jiven Basi, Sohail Sidhu, Parkash Ragsdale, Arden Barry, Rob Pammett
Publikováno v:
INNOVATIONS in Pharmacy, Vol 15, Iss 3 (2024)
Background Recent changes to legislation in British Columbia (BC) have expanded the scope of pharmacist-provided services to include pharmacist prescribing for minor ailments and contraception (PPMAC). The purpose of this study was to gather communit
Externí odkaz:
https://doaj.org/article/066a294255bf4467b71438df6146f63b
Autor:
Gita Mahmoudabadi, Kelsey Homyk, Adam B. Catching, Ana Mahmoudabadi, Helen Bermudez Foley, Arbel D. Tadmor, Rob Phillips
Publikováno v:
Frontiers in Microbiomes, Vol 3 (2024)
Metagenomic studies have revolutionized the study of novel phages. However these studies trade depth of coverage for breadth. We show that the targeted sequencing of a small region of a phage terminase family can provide sufficient sequence diversity
Externí odkaz:
https://doaj.org/article/394e9a90a94e4a30a70d306ec98c79aa
Autor:
Kirsten A. Thus, Hester A. de Groot-Kruseman, Pauline Winkler-Seinstra, Marta Fiocco, Heidi Segers, Cor van den Bos, Inge M. van der Sluis, Wim J.E. Tissing, Margreet A. Veening, Christian Michel Zwaan, Cornelis M. van Tilburg, Rob Pieters, Marc Bierings
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Infections lead to substantial morbidity during treatment of acute lymphoblastic leukemia (ALL) in which the adaptive immune system gets severely affected, leading to declining serum immunoglobulin levels. The aim of this trial was to investigate whe
Externí odkaz:
https://doaj.org/article/634bb1c123c8458d9d413f68bd657421