Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rob Maile"'
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Smoke inhalation injury increases overall burn mortality by up to 20 times. Current therapy remains supportive with a failure to identify an optimal or targeted treatment protocol for smoke inhalation injury. The goal of this revi
Externí odkaz:
https://doaj.org/article/25487ec5a5c94197999a61ebac85be80
Autor:
Rob Maile, Brooke R. Dandurand, Alexandra Mercel, Jenna M Weiss, Nick D. Tsihlis, Kui Sun, David C. Gillis, Melina R. Kibbe
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
Smoke inhalation injury increases morbidity and mortality. Clinically relevant animal models are necessary for the continued investigation of the pathophysiology of inhalation injury and the development of therapeutics. The goal of our research was t
Publikováno v:
Journal of Burn Care & Research. 43:S31-S31
Introduction Severe burn injury leads to many systemic stresses that can seriously impact multiple systems throughout the body. These stresses are further exacerbated if there is a combined burn and inhalation injury, which leads to increased morbidi
Autor:
Smaranda Willcox, Melina R. Kibbe, Rob Maile, Samuel I. Stupp, Erica B. Peters, Kui Sun, Kathleen Marulanda, David C. Gillis, Mark R. Karver, Alexandra Mercel, Nick D. Tsihlis, Tristan D. Clemons, Jack D. Griffith
Publikováno v:
Biomaterials
Smoke inhalation injury is associated with significant mortality and current therapies remain supportive. The purpose of our study was to identify proteins upregulated in the lung after smoke inhalation injury and develop peptide amphiphile nanofiber
Autor:
Edward J. Collins, Rob Maile, Jeffrey A. Frelinger, Thomas B. Kepler, David S. Riddle, Benjamin G. Vincent, Peter J. Miller
Publikováno v:
European Journal of Immunology. 38:1511-1521
CD8 plays an important role in the activity of cytolytic T cells (CTL). However, whether or not CD8 is required for the development of CTL has not been clearly determined. Cytotoxic activity in the CD8alpha knockout mouse is difficult to induce, and
Publikováno v:
Journal of the American College of Surgeons. 223:S154-S155
Autor:
Rob Maile, R. M. Wardrop, Tong Gui, Jeffrey A. Frelinger, Paul E. Monahan, Tai-Ping Zhang, Darrel W. Stafford, Da-Yun Jin
Publikováno v:
Gene therapy. 14(5)
Immune responses leading to antibody-mediated elimination of the transgenic protein are a concern in gene replacement for congenital protein deficiencies, for which hemophilia is an important model. Although most hemophilia B patients have circulatin
Autor:
Brandon Linz, Rob Maile, Bruce A. Cairns, Jenny P.-Y. Ting, April E. Mendoza, Willie June Brickey, Laurel B. Kartchner
Publikováno v:
Journal of Surgical Research. 179:327-328
Autor:
Willie June Brickey, C.J. Neely, Jenny P.-Y. Ting, April E. Mendoza, Rob Maile, Bruce A. Cairns
Publikováno v:
Journal of Surgical Research. 172:259-260
Autor:
Jeffrey A. Frelinger, Rob Maile, Edward J. Collins, Anthony A. Meyer, Bruce A. Cairns, Suzan deSerres, Ian B. Buchanan, David Pilati
Publikováno v:
Surgery. 130(2)
Background. Previous studies suggest that CD8+ T cells are immunosuppressive after burn injury, but recent reports indicate that CD8+ T cells have several functions similar to CD4+ T cells, including the secretion of cytokines. This study uses HY mal